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Solubility Determination and Correlation of 1,3,5-Tribromobenzene in Five Kinds of Binary Mixed Solvents

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Abstract

The solubility of 1,3,5-Tribromobenzene (m-TBB) in five kinds of binary solvent mixtures (i.e., N,N-dimethylformamide (DMF) + water, N,N-dimethylacetamide (DMA) + water, 1,4-dioxane + water, DMF + ethanol, and DMA + ethanol) was measured by a gravimetric method. The determination was carried out at temperatures ranging from 288.15 K to 323.15 K under ambient pressure. The solubility data were positively correlated with the molar fraction of good solvent and temperature. The order of solubility is 1,4-dioxane + water > DMA + ethanol > DMF + ethanol > DMA + water > DMF + water. The solubility of m-TBB was negatively correlated with solvent polarity. Four thermodynamic models (including the Jouyban–Acree–Apelblat, the Sun model, the NRTL model, and the Wilson model) were selected to correlate the solubility data of m-TBB. The solubility data are of great significance for solvent selection and yield judgment.

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Acknowledgements

This investigation work received support from the National Natural Science Foundation of China (Grant reference: 82204288), Shandong Provincial Natural Science Foundation (Grant reference: ZR2023MB036), Central Guidance on Local Science and Technology Development Fund of Shandong Province (Grant reference: YDZX2022098), Science, Education and Industry Integration Technology Innovation Project (2022PT117). Talent Research Project of Qilu University of Technology (Grant reference: 2023RCKY088).

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Authors and Affiliations

  1. School of Pharmaceutical Sciences (Shandong Analysis and Test Center), Qilu University of Technology (Shandong Academy of Sciences), Jinan, 250014, People’s Republic of China

    Xian Sun, Xingzhu Wang, Shuai Yu & Fumin Xue

  2. School Pharmaceutical Sciences, Shandong University, Jinan, 250012, People’s Republic of China

    Shuai Yu

  3. Shandong Jingbo Agrochemicals Technology Co., Ltd, Binzhou, 256500, People’s Republic of China

    Shuai Yu

  4. Technology Center of Qingdao Customs District, Qingdao, 266599, People’s Republic of China

    Min Wan

  5. Department of Respiratory, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan, 250000, China

    Degan Lu

  6. Chemical Technology Research Institute of Shandong, Qingdao University of Science & Technology, Jinan, 250014, China

    Wenguo Xing

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  1. Xian Sun
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  2. Xingzhu Wang
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  3. Min Wan
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  4. Degan Lu
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  5. Wenguo Xing
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  6. Shuai Yu
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  7. Fumin Xue
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Contributions

Xian Sun contributed toward conceptualization, methodology, formal analysis, software, investigation, and writing - original draft. Xingzhu Wang contributed toward conceptualization, and methodology. Min Wan contributed toward investigation and methodology. Degan Lu contributed toward investigation and methodology. Wenguo Xing contributed toward investigation and methodology. Shuai Yu contributed toward conceptualization, methodology, formal analysis, software, investigation, writing - original draft, visualization, supervision, and funding acquisition. Fumin Xue contributed toward resources, and project administration.

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Correspondence to Shuai Yu or Fumin Xue.

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Sun, X., Wang, X., Wan, M. et al. Solubility Determination and Correlation of 1,3,5-Tribromobenzene in Five Kinds of Binary Mixed Solvents. J Solution Chem (2024). https://doi.org/10.1007/s10953-024-01370-y

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