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Hopf bifurcation and multiple limit cycles in bio-chemical reaction of the morphogenesis process

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Abstract

Morphogenetic process is an interesting but very hard bio-chemical problem. In this paper, we consider a bio-chemical model in temporal morphogenesis which is a generalization of the model studied by Gierer–Meinhardt. By using the theory of ordinary differential equations, it is shown that the model undergoes a Hopf bifurcation if the parameters in the model satisfy the following relationship: λ = 2/(ρ 2x*)−1. It is also proved that the close orbit created by the Hopf bifurcation is stable. The conditions that guarantee the system has three closely nested limit cycles are also obtained in the paper.

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References

  1. Gierer A., Meinhardt H.: A theory of biological pattern formation. Kybernetik 12, 30–39 (1972)

    Article  CAS  Google Scholar 

  2. Granero-Porati M.I., Porati A.: Temporal organization in a morphogenetic field. J. Math. Biol. 20, 153–157 (1984)

    Article  Google Scholar 

  3. Berding C., Haken H.: Pattern formation in morphogenesis. J. Math. Biol. 14, 133–151 (1981)

    Article  Google Scholar 

  4. Huang X.: A Mathematical Model in Morphogenetic Processes, Lectures on Mathematical Biology. Universida Simon Bolivar, Caracas (2001)

    Google Scholar 

  5. Huang X., Wang Y., Su H.: Limit cycles in morphogenesis. Nonlinear Anal. Real World Appl. 8, 1341–1348 (2007)

    Article  Google Scholar 

  6. Huang X., Zhu L.: Limit cycles in a general Kolmogorov model. Nonlinear Anal. Theory Methods Appl. 60(8), 1393–1414 (2005)

    Article  Google Scholar 

  7. Mon G.M., Zhou H.: An approximate solution and its applications of differential equations with small parameter. J. Yangzhou Univ. 2(3), 7–9 (1999) (in Chinese)

    Google Scholar 

  8. May R.: Limit cycles in predator-prey communities. Science 177, 900–902 (1972)

    Article  Google Scholar 

  9. Huang X., Zhu L.: A three-dimensional chemostat with quadratic yields. J. Math. Chem. 38(3), 399–412 (2005)

    Article  CAS  Google Scholar 

  10. Huang X., Merrill S.J.: Conditions for uniqueness of limit cycles in general predator-prey system. Math. Biosci. 96, 47–60 (1989)

    Article  CAS  Google Scholar 

  11. Huang X.: Stability of a general predator-prey model. J. Franklin Inst. 327(5), 751–769 (1990)

    Article  Google Scholar 

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Correspondence to Xuncheng Huang.

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Wang, S., Huang, X., Zhu, L. et al. Hopf bifurcation and multiple limit cycles in bio-chemical reaction of the morphogenesis process. J Math Chem 47, 739–749 (2010). https://doi.org/10.1007/s10910-009-9597-2

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  • DOI: https://doi.org/10.1007/s10910-009-9597-2

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