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Development of Novel Green Synthesized Silver Nanoparticles with Superior Antibacterial and Wound Healing Properties in Nursing Care After Rectal Surgery

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Abstract

The present investigation showed the green synthesis of silver nanoparticles (AgNPs) using Ficus benghalensis (F. benghalensis) leaf extract. UV–Vis spectra of the biofabricated AgNPs displayed its maximum peak of absorption at 461 nm. High resolution-transmission electron microscopy images displayed the shape of AgNPs as spherical with an average diameter of 35 nm size. The analysis of X-ray diffraction confirmed the presence of crystalline AgNPs. The analysis of Fourier-transform infrared spectroscopy confirmed the existence of bioconstituents such as terpenoids, phenolics and flavonoids, which functions as bio-reducing agents. When compared with F. benghalensis extract, AgNPs displayed the considerably greater bioactivities. The exceptional antimicrobial functionalities of AgNPs against both the gram positive and gram negative bacteria makes them appropriate candidates for the production of antibiotics against the species that are resistant to traditional antibiotics. The assay of HDFa cell scratch confirmed that the AgNPs have greater ability of wound healing than the leaf extract of F. benghalensis. Altogether, the obtained results showed the application of synthesized AgNPs in the production of novel drugs that are used for wound healing in nursing care after rectal surgery.

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The data generated or analyzed during the present work was available on reasonable request from the corresponding author.

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The authors declare that no funds, grants, or other support were received related to this work.

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Authors and Affiliations

  1. Fanwei Village, Hanshan Town, Shuyang County, Suqian City, 223631, Jiangsu Province, China

    Hongwei Lu

  2. The Second Department of Internal Medicine, Linyi Cancer Hospital, NO. 6, Lingyuan East Street, Lanshan District, Linyi, 276001, Shandong Province, China

    Shumei Liu & Yujie Zhang

Authors
  1. Hongwei Lu
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  2. Shumei Liu
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  3. Yujie Zhang
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Contributions

All authors equally contributed to the design and study conception. Analysis, data collection and material preparation were performed by HL. The first draft of the manuscript was written and revised by HL, SL, YZ. All authors read and approved the final manuscript.

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Correspondence to Yujie Zhang.

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Lu, H., Liu, S. & Zhang, Y. Development of Novel Green Synthesized Silver Nanoparticles with Superior Antibacterial and Wound Healing Properties in Nursing Care After Rectal Surgery. J Inorg Organomet Polym 32, 773–780 (2022). https://doi.org/10.1007/s10904-022-02223-1

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  • DOI: https://doi.org/10.1007/s10904-022-02223-1

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