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Emerging Opportunities in the Biomedical Applications of Dendrimers

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Abstract

The medical field remains challenged with many unmet needs, prompting rigorous research for solutions. Dendrimers are emerging as innovative solutions to many unmet clinical needs. Indeed, commercial dendrimer-enabled gene transfection technologies exist and work is ongoing to translate many other dendrimer products into the market to assist patients. Here, we review the ongoing work on dendrimer-enabled drug delivery technologies, diagnostic platforms, and antimicrobial agents. Our goal is to inspire the continuous exploration of the dendritic scaffold to address many issues in the biomedical landscape.

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Reproduced from Ref. [87] with permission from the American Chemical Society

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Reproduced from Ref. [90] with permission from The Royal of Society of Chemistry

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Reproduced from Ref. [107] with permission from Elsevier B.V

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Acknowledgements

We thank the Natural Sciences and Engineering Research Council of Canada for support.

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Authors and Affiliations

  1. Department of Chemistry, University of Prince Edwards Island, 550 University Avenue, Charlottetown, Prince Edwards Island, C1A 4P3, Canada

    Alaa S. Abd-El-Aziz

  2. School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, 02138, USA

    Christian Agatemor

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Correspondence to Alaa S. Abd-El-Aziz.

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This paper is dedicated to Professor George Newkome in recognition of his outstanding contribution to the field of dendrimers.

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Abd-El-Aziz, A.S., Agatemor, C. Emerging Opportunities in the Biomedical Applications of Dendrimers. J Inorg Organomet Polym 28, 369–382 (2018). https://doi.org/10.1007/s10904-017-0768-5

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