Skip to main content
SpringerLink
Log in

The Effect of Carbon Nanotubes added into Bullfrog Collagen Hydrogel on Gentamicin Sulphate Release: In Vitro

  • Published:
Journal of Inorganic and Organometallic Polymers and Materials Aims and scope Submit manuscript

Abstract

We demonstrate the preparation and its drug delivery behavior of this novel hybrid collagen-carbon nanotubes (CNTs) hydrogel obtained. CNTs can be taken as an additive to enhance the stability of the hybrid hydrogel. As a result, the sustained release effects of the hybrid hydrogel on gentamicin sulphate were significantly improved. The hybrid hydrogel combined the excellent safety of bullfrog collagen and the enhanced stability of CNTs brought to the hybrid hydrogel. It suggests that the hybrid collagen hydrogel with CNTs could be used as a novel kind of drug delivery matrix.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4

Similar content being viewed by others

References

  1. L.M. Ericson, H. Fan, H. Peng, V.A. Davis, W. Zhou, J. Sulpizio, Y. Wang, R. Booker, J. Vavro, C. Guthy et al., Science 305, 1447 (2004)

    Article  CAS  Google Scholar 

  2. K. Hong, S.H. Kim, C. Yang, W.M. Yun, S. Nam, J. Jang, C. Park, C.E. Park, ACS Appl. Mater. Interfaces 3, 74 (2011)

    Article  CAS  Google Scholar 

  3. A.D.L. Zerda, Z. Liu, S. Bodapati, R. Teed, S. Vaithilingam, B.T. Khuri-Yakub, X.Y. Chen, H.J. Dai, S.S. Gambhir, Nano Lett. 10, 2168 (2010)

    Article  Google Scholar 

  4. A.A. Bhirde, V. Patel, J. Gavard, G.F. Zhang, A.A. Sousa, A. Masedunskas, R.D. Leapman, R. Weigert, J.S. Gutkind, J.F. Rusling, ACS Nano 3, 307 (2009)

    Article  CAS  Google Scholar 

  5. S.V. Vlierberghe, P. Dubruel, E. Schacht, Biomacromolecules 12, 1387 (2011)

    Article  Google Scholar 

  6. H. Kang, H.P. Liu, X.L. Zhang, J.L. Yan, Z. Zhu, L. Peng, H.H. Yang, Y. Kim, W.H. Tan, Langmuir 27, 399 (2011)

    Article  CAS  Google Scholar 

  7. H. Li, B.L. Liu, L.Z. Gao, H.L. Chen, Food Chem. 84, 65 (2004)

    Article  CAS  Google Scholar 

  8. H. Li, D.Q. Wang, B.L. Liu, L.Z. Gao, Coll. Surf. B 33, 85 (2004)

    Article  CAS  Google Scholar 

  9. H. Li, Q. Liang, L.Z. Gao, S.H. Tang, Z.Y. Cheng, B.L. Zhang, Z.L. Yu, C.F. Ng, C.T. Au, Catal. Lett. 74, 185 (2001)

    Article  CAS  Google Scholar 

  10. S.S. Sampath, D.H. Robinson, J. Pharm. Sci. 79, 428 (1990)

    Article  CAS  Google Scholar 

Download references

Acknowledgments

We are grateful for the financial support of the Natural Science Foundation of China (No. 81000976), the Natural Science Foundation of Shandong Province (No. ZR2010BM030, ZR2010BQ010), and the Science and Technology Research Project of Shandong Provincial Education Department (Grant No. J08LC54).

Author information

Authors and Affiliations

  1. School of Life and Medical Sciences, University of Jinan, Jinan, 250022, People’s Republic of China

    He Li

  2. School of Chemistry and Chemical Engineering, University of Jinan, Jinan, 250022, China

    He Li, Jing He, Yanfang Zhao, Gaolei Wang & Qin Wei

Authors
  1. He Li
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Jing He
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Yanfang Zhao
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Gaolei Wang
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Qin Wei
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to He Li.

Additional information

Presented in part at the 1st International Congress on Advanced Materials held in Jinan, PRC, from May 12–17, 2011.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Li, H., He, J., Zhao, Y. et al. The Effect of Carbon Nanotubes added into Bullfrog Collagen Hydrogel on Gentamicin Sulphate Release: In Vitro. J Inorg Organomet Polym 21, 890–892 (2011). https://doi.org/10.1007/s10904-011-9522-6

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10904-011-9522-6

Keywords

Search

Navigation