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Recent Applications of Quantum Dots in Pharmaceutical Analysis

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Abstract

Nanotechnology has emerged as one of the most potential areas for pharmaceutical analysis. The need for nanomaterials in pharmaceutical analysis is comprehended in terms of economic challenges, health and safety concerns. Quantum dots (QDs)or colloidal semiconductor nanocrystals are new groups of fluorescent nanoparticles that bind nanotechnology to drug analysis. Because of their special physicochemical characteristics and small size, QDs are thought to be promising candidates for the electrical and luminescent probes development. They were originally developed as luminescent biological labels, but are now discovering new analytical chemistry applications, where their photo-luminescent properties are used in pharmaceutical, clinical analysis, food quality control and environmental monitoring. In this review, we discuss QDs regarding properties and advantages, advances in methods of synthesis and their recent applications in drug analysis in the recent last years.

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Abbreviations

GCE :

Glassy carbon electrode

GQDs :

Graphene quantum dots

HBNNS :

hexagonal boron nitride nanosheets

MIP :

Molecularly imprinted polymer

MPA :

Mercaptopropionic acid

MP S :

3-Mercapto-1-propanesulfonic acid

MSA :

Mercaptosuccinic acid

MWCNT :

Multiwall carbon nanotubes

N, S-CQDs :

Nitrogen and sulfur carbon quantum dots

PL :

Photoluminescence intensity

PEDOT :

Poly (3,4-ethylenedioxythiophene)

RH-CQDs :

Rice husk carbon quantum dots

SEM :

Scanning electron microscopy

SMIP :

Silica molecular imprinted polymer

TEM :

Transmission electron microscopy

TGA :

Thioglycolic acid

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Authors and Affiliations

  1. Department of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, 35516, Egypt

    Fathalla Belal

  2. Department of pharmaceutical analytical Chemistry, Faculty of Pharmacy, Tanta University, Tanta, Egypt

    Mokhtar Mabrouk & Sherin Hammad

  3. Pharmaceutical Analysis Department, Faculty of Pharmacy, Menoufia University, Menoufia, Egypt

    Hytham Ahmed & Aya Barseem

Authors
  1. Fathalla Belal
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  2. Mokhtar Mabrouk
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  3. Sherin Hammad
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  4. Hytham Ahmed
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  5. Aya Barseem
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Contributions

Fathalla Belal: Conceptualization, Review & editing, Supervision. Mokhtar Mabrouk: Conceptualization, Review & editing, Supervision. Sherin Hammad: Conceptualization, Review & editing, Supervision. Aya Barseem: Conceptualization, Visualization, Writing - original draft. Hytham Ahmed: Conceptualization, Review & editing, Supervision.

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Belal, F., Mabrouk, M., Hammad, S. et al. Recent Applications of Quantum Dots in Pharmaceutical Analysis. J Fluoresc 34, 119–138 (2024). https://doi.org/10.1007/s10895-023-03276-2

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