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Synthesis of Fluorescent Gold Nanoclusters Directed by Bovine Serum Albumin and Application for Nitrite Detection

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Abstract

In the present work, gold nanocluster (GNC) induced by bovine serum albumin (BSA) was synthesized as a novel fluorescence probe to detect nitrite (NO2 −) sensitively and selectively. The fluorescence of GNC was found to be quenched effectively by NO2 −. Under the optimum conditions, it was found that the change of fluorescence intensity was proportional with the concentration of NO2 − in the linear range of 0.1–50 μM (R = 0.9990), with a detection limit (S/N = 3) of 30 nM. The absorption spectroscopy, circular dichroism (CD), and X-ray photoelectron spectroscopy (XPS) studies were employed to discuss the quenching mechanism. In addition, the present approach was successfully applied in real water samples.

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Acknowledgments

Q. Yue and J. Liu thank Natural Science Foundation of China for Funding (21005036, 20875042, 21075058, 21127006). This work was also supported by Natural Science Foundation (ZR2010BZ004, JQ201106), Research Fund of Shandong Academy of Agricultural Sciences and Doctoral Fund of Liaocheng University.

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Authors and Affiliations

  1. Department of Chemistry, Liaocheng University, Liaocheng, 252059, People’s Republic of China

    Qiaoli Yue, Lijun Sun, Tongfei Shen & Jifeng Liu

  2. Shandong Provincial Key Lab of Test Technology on Food Quality and Safety, Shandong Academy of Agricultural Sciences, Jinan, 250100, China

    Xiaohong Gu & Shuqiu Zhang

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  1. Qiaoli Yue
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  2. Lijun Sun
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  3. Tongfei Shen
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  4. Xiaohong Gu
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  5. Shuqiu Zhang
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  6. Jifeng Liu
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Correspondence to Jifeng Liu.

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Yue, Q., Sun, L., Shen, T. et al. Synthesis of Fluorescent Gold Nanoclusters Directed by Bovine Serum Albumin and Application for Nitrite Detection. J Fluoresc 23, 1313–1318 (2013). https://doi.org/10.1007/s10895-013-1265-z

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  • DOI: https://doi.org/10.1007/s10895-013-1265-z

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