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A New Pyrazoline-Based Fluorescent Probe for Cu2+ in Live Cells

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Abstract

A new pyrazoline-based probe was synthesized and the structure was determined by using X-ray diffraction analysis. The probe responds to Cu2+ in aqueous medium in “turn-off” fluorescent manner with selectivity and sensitivity. Furthermore, the probe could be used for real-time tracking of Cu2+ in Hela cells.

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Acknowledgments

This study was supported by 973 Program (2010CB933504) and National Natural Science Foundation of China (90813022 and 20972088).

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Authors and Affiliations

  1. Institute of Organic Chemistry, School of Chemistry and Chemical Engineering, Shandong University, Jinan, 250100, People’s Republic of China

    Meng-Meng Li, Hui Ye, Fei Ge & Bao-Xiang Zhao

  2. Institute of Developmental Biology, School of Life Science, Shandong University, Jinan, 250100, People’s Republic of China

    Shu-Ya Huang & Jun-Ying Miao

Authors
  1. Meng-Meng Li
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  2. Shu-Ya Huang
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  3. Hui Ye
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  4. Fei Ge
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  5. Jun-Ying Miao
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  6. Bao-Xiang Zhao
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Corresponding authors

Correspondence to Jun-Ying Miao or Bao-Xiang Zhao.

Additional information

Meng-Meng Li and Shu-Ya Huang contributed equally.

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Li, MM., Huang, SY., Ye, H. et al. A New Pyrazoline-Based Fluorescent Probe for Cu2+ in Live Cells. J Fluoresc 23, 799–806 (2013). https://doi.org/10.1007/s10895-013-1203-0

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  • DOI: https://doi.org/10.1007/s10895-013-1203-0

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