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Early Emotional, Behavioural and Social Development of Infants and Young Children with Congenital Heart Disease: A Systematic Review

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Abstract

The experiences of diagnosis of congenital heart disease (CHD), cardiac surgery and hospitalisation(s) are distressing and represent a significant stressor for a child and family, which may impact psychosocial development. This systematic review provides a synthesis of psychosocial outcomes of infants and young children with congenital heart disease who had cardiac surgery early in life. Twenty-eight studies related to infant and young children’s psychosocial development, specifically emotional, social and behavioural functioning were identified. Variability was related to methodological factors including differences in study design, varying measurement tools and heterogeneous samples. Despite these limitations, the majority of studies were of high quality. The most common finding was a high prevalence of low-severity emotional and behavioural dysregulation. Young children with severe CHD or comorbid conditions experienced greater impairment, with higher rates of externalising behaviour problems, although internalising behaviour problems were also evident. This review integrates findings from literature in the past 28 years on the psychosocial well-being of infants and young children with CHD and demonstrates a risk for emotional, social and behavioural development difficulty, and, importantly, that symptoms of psychosocial impairment are detectable very early in infancy. We advocate for assessment and monitoring of emotional and behavioural regulation and social development to be routinely conducted from infancy to enable prevention and early intervention.

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References

References marked with an asterisk * indicate studies included in the review

  • Achenbach, T. M., & Rescorla, L. A. (2000). Child behavior checklist for ages 11/2–5. Burlington: University of Vermont.

    Google Scholar 

  • *Alton, G. Y., Rempel, G. R., Robertson, C. M. T., Newburn-Cook, C. V., & Norris, C. M. (2010). Functional outcomes after neonatal open cardiac surgery: Comparison of survivors of the Norwood staged procedure and the arterial switch operation. Cardiology in the Young, 20, 668–675.

    PubMed  Google Scholar 

  • *Alton, G. Y., Taghados, S., Joffe, A. R., Robertson, C. M. T., Dinu, I., & the Western Canadian Pediatric Therapies Follow-up Group. (2015). Prediction of preschool functional abilities after early complex cardiac surgery. Cardiology in the Young, 25, 655–662.

    PubMed  Google Scholar 

  • Australian Institute of Health and Welfare. (2017). Heart, stroke and vascular diseases. Retrieved June 2018, from https://www.aihw.gov.au/reports-data/health-conditions-disability-deaths/heart-stroke-vascular-diseases/overview.

  • Bayer, J., Hiscock, H., Scalzo, K., Mathers, M., McDonald, M., Morris, A., … Wake, M. (2009). Systematic review of preventive interventions for children’s mental health: What would work in Australian contexts? Australian and New Zealand Journal of Psychiatry, 43, 695–710.

    PubMed  Google Scholar 

  • *Bellinger, D. C., Rappaport, L. A., Wypij, D., Wernovsky, G., & Newburger, J. W. (1997). Patterns of developmental dysfunction after surgery during infancy to correct transposition of the great arteries. Developmental and Behavioral Pediatrics, 18, 75–83.

    CAS  Google Scholar 

  • Bellinger, D. C., Wypij, D., duPlessis, A. J., Rappaport, L. A., Jonas, R. A., Wernovsky, G., & Newburger, J. W. (2003). Neurodevelopmental status at 8 years in children with dextro-transposition of the great arteries: The Boston Circulatory Arrest Trial. Journal of Thoracic and Cardiovascular Surgery, 126, 1385–1396.

    PubMed  Google Scholar 

  • Brandlistuen, R. E., Stene-Larsen, K., Holmstrom, H., Landolt, M. A., Eskedal, L. T., & Vollrath, M. E. (2010). Symptoms of communication and social impairment in toddlers with congenital heart defects. Child: Care, Health and Development, 37, 37–43.

    Google Scholar 

  • *Brandlistuen, R. E., Stene-Larsen, K., Holmstrøm, H., Landolt, M. A., Eskedal, L. T., & Vollrath, M. E. (2011). Occurrence and predictors of developmental impairments in 3-year-old children with congenital heart defects. Journal of Developmental and Behavioral Pediatrics, 32, 526–532.

    PubMed  Google Scholar 

  • *Brosig, C. L., Mussatto, K. A., Kuhn, E. M., & Tweddell, J. S. (2007). Neurodevelopmental outcome in preschool survivors of complex congenital heart disease: Implications for clinical practice. Journal of Pediatric Health Care, 21, 3–12.

    PubMed  Google Scholar 

  • Calkins, S. D., & Hill, A. L. (2007). Caregiver influences on emerging emotion regulation: Biological and environmental transactions in early development. In J. Gross (Ed.), Handbook of emotion regulation (pp. 229–248). New York: The Guilford Press.

    Google Scholar 

  • Casey, F. A., Sykes, D. H., Craig, B. G., Power, R., & Mulholland, H. C. (1996). Behavioral adjustment of children with surgically palliated complex congenital heart disease. Journal of Pediatric Psychology, 21, 335–352.

    CAS  PubMed  Google Scholar 

  • Celermajer, D., Strange, G., Cordina, R., Selbie, L., Sholler, G., Winlaw, D., … d’Udekem, Y. (2016). Congenital Heart Disease requires a lifetime continuum of care: A call for a regional registry. Heart, Lung and Circulation, 25, 750–754.

    PubMed  Google Scholar 

  • *Claessens, N. H. P., Algra, S. O., Ouwehand, T. L., Jansen, N. J. G., Schappin, R., Haas, F., … Benders, M. J. N. L. (2018). Perioperative neonatal brain injury is associated with worse school-age neurodevelopment in children with critical congenital heart disease. Developmental Medicine and Child Neurology, 60, 1052–1058.

    PubMed  Google Scholar 

  • Corno, A. F., & Utens, E. M. W. J. (2018). Editorial: Neuro-development and psychological issues in congenital heart defects. Frontiers in Pediatrics, 5, 1–2.

    Google Scholar 

  • DeMaso, D. R., Calderon, J., Taylor, G. A., Holland, J. E., Stopp, C., White, M. T., … Newburger, J. W. (2017). Psychiatric disorders in adolescents with single ventricle congenital heart disease. Pediatrics, 139, e20162241.

    PubMed  PubMed Central  Google Scholar 

  • Dopfner, M., Berner, W., Fleischmann, T., & Schmidt, M. (1993). Verhaltensbeurteilungsbogen fur Vorschulkinder (VBV 3-6). Weinheim: Beltz.

    Google Scholar 

  • De Young, A. C., Kenardy, J. A., & Cobham, V. E. (2011). Diagnosis of posttraumatic stress disorder in preschool children. Journal of Clinical Child and Adolescent Psychology, 40, 375–384.

    PubMed  Google Scholar 

  • *Eagleson, K. J., Justo, R. N., Ware, R. S., Johnson, S. G., & Boyle, F. M. (2013). Health-related quality of life and congenital heart disease in Australia. Journal of Paediatrics and Child Health, 49I, 856–864.

    Google Scholar 

  • Ernst, M., Marino, B., Cassedy, A., Piazza-Waggoner, C., Franklin, R., Brown, K., & Wray, J. (2018). Biopsychosocial predictors of Quality of Life outcomes in pediatric congenital heart disease. Pediatric Cardiology, 39, 79–88.

    PubMed  Google Scholar 

  • Fekkes, M., Theunissen, N. C. M., Brugman, E., Veen, S., Verrips, E. G. H., Koopman, H. M., … Verloove-Vanhorick, S. P. (2000). Development and psychometric evaluation of the TAPQOL: A health-related quality of life instrument for 1- to 5-year-old children. Quality of Life Research, 9, 961–972.

    CAS  PubMed  Google Scholar 

  • Gardner, F. V., Freeman, N. H., Black, A. M. S., & Angelini, G. D. (1996). Disturbed mother–infant interaction in association with congenital heart disease. Heart, 76, 56–59.

    CAS  PubMed  PubMed Central  Google Scholar 

  • *Gaynor, J. W., Nord, A. S., Wernovsky, G., Bernbaum, J., Solot, C. B., Burnham, N., … Gerdes, M. (2009). Apolipoprotein E genotype modifies the risk of behavior problems after infant cardiac surgery. Pediatrics, 124, 241–250.

    PubMed  PubMed Central  Google Scholar 

  • Girard, J. M., & Cohen, J. F. (2016). A primer on observational measurement. Assessment, 23, 404–413.

    PubMed  PubMed Central  Google Scholar 

  • Goldberg, S., Janus, M., Washington, J., Simmons, R. J., MacLusky, I., & Fowler, R. S. (1997). Prediction of preschool behavioral problems in healthy and pediatric samples. Developmental and Behavioral Pediatrics, 18, 304–313.

    CAS  Google Scholar 

  • *Goldsworthy, M., Franich-Ray, C., Kinney, S., Shekerdemian, L., Beca, J., & Gunne, J. (2016). Development in 2-year-olds with congenital heart disease. Congenital Heart Disease, 11, 378–385.

    PubMed  Google Scholar 

  • Green, J. L., Knight, S., McCarthy, M. C., & DeLuca, C. D. (2013). Motor functioning during and following chemotherapy treatment for pediatric acute lymphoblastic leukemia. Pediatric Blood & Cancer, 60, 1261–1266.

    Google Scholar 

  • Guedeney, A., & Fermanian, J. (2001). A validity and reliability study of assessment and screening for sustained withdrawal reaction in infancy: The Alarm Distress Baby Scale. Infant Mental Health Journal, 22, 559–575.

    Google Scholar 

  • *Guerra, G. G., Robertson, C. M. T., Alton, G. Y., Joffe, A. R., Dinu, I. A., Nicholas, D., … Rebeyka, I. M. (2013). Quality of life 4 years after complex heart surgery in infancy. The Journal of Thoracic and Cardiovascular Surgery, 145, 482–488.

    Google Scholar 

  • *Guerra, G. G., Joffe, A. R., Robertson, C. M. T., Atallah, J., Alton, G., Sauve, R. S., … Rebeya, I. M. (2014). Health-related quality of life experienced by children with chromosomal abnormalities and congenital heart defects. Pediatric Cardiology, 35, 536–541.

    Google Scholar 

  • Harrison, P. L., & Oakland, T. (2003). Manual for the adaptive behavior assessment system II. PsychCorp. San Antonia: Harcourt Assessment Inc.

    Google Scholar 

  • *Harrison, T. (2013). Autonomic nervous system function, child behavior, and maternal sensitivity in three-year-old children with surgically corrected transposition. Heart and Lung, 42, 414–421.

    PubMed  Google Scholar 

  • *Hulser, K., Dubowy, K., Knobl, H., Meyer, H., & Scholmerich, A. (2007). Developmental outcomes and psychosocial adjustment in children after surgery for congenital heart disease during infancy. Journal of Reproductive and Infant Psychology, 25, 139–151.

    Google Scholar 

  • *Ikle, L., Hale, K., Fashaw, L., Boucek, M., & Rosenberg, A. A. (2003). Developmental outcome of patients with hypoplastic left heart syndrome treated with heart transplantation. The Journal of Pediatrics, 142, 20–25.

    PubMed  Google Scholar 

  • Ingerski, L. M., Shaw, K., Gray, W. N., & Janicke, D. M. (2010). A pilot study comparing traumatic stress symptoms by child and parent report across pediatric chronic illness groups. Developmental and Behavioral Pediatrics, 31, 713–719.

    Google Scholar 

  • Jackson, C., Cheater, F. M., & Reid, I. (2008). A systematic review of decision support needs of parents making child health decisions. Health Expectations, 11, 232–251.

    PubMed  PubMed Central  Google Scholar 

  • Jordan, B., Franich-Ray, C., Albert, N., Anderson, V., Northam, E., Cochrane, A., & Menahem, S. (2014). Early mother–infant relationships after cardiac surgery in infancy. Archives of Disease in Childhood, 99, 641–645.

    PubMed  Google Scholar 

  • Jordan, B., Franich-Ray, C., Anderson, V., Northam, E., Albert, N., Cochrane, A., & Menahem, S. (2013). Maternal report of infant emotional well-being following their infant’s hospitalization for neonatal cardiac surgery. Infant Mental Health Journal, 34, 259–266.

    Google Scholar 

  • Karsdorp, P. A., Everaerd, W., Kindt, M., & Mulder, B. J. M. (2007). Psychological and cognitive functioning in children and adolescents with congenital heart disease: A Meta-Analysis. Journal of Pediatric Psychology, 32, 527–541.

    PubMed  Google Scholar 

  • Kern, J. H., Hinton, V. J., Nereo, N. E., Hayes, C. J., & Gersony, W. M. (1998). Early developmental outcome after the Norwood procedure for hypoplastic left heart syndrome. Pediatrics, 102, 1148–1152.

    CAS  PubMed  Google Scholar 

  • Kim, D. S., Yatong, K. L., Kim, J. H., Bergquist, C. S., Gerdes, M., Bernbaum, J. C., … Gaynor, J. W. (2018). Autosomal dominant mannose-binding lectin deficiency is associated with worse neurodevelopmental outcomes after cardiac surgery in infants. The Journal of Thoracic and Cardiovascular Surgery, 155, 1139–1147.

    CAS  PubMed  Google Scholar 

  • Landgraf, J. M., Abetz, L., & Ware, J. E. (1996). The CHQ user’s manual (1st ed.). Boston: The Health Institute, New England Medical Center.

    Google Scholar 

  • Latal, B., Helfricht, S., Fischer, J. E., Bauersfeld, U., & Landolt, M. A. (2009). Psychological adjustment and quality of life in children and adolescents following open-heart surgery for congenital heart disease: A systematic review. BMC Pediatrics, 9, 6.

    PubMed  PubMed Central  Google Scholar 

  • Long, A. F., & Godfrey, M. (2004). An evaluation tool to assess the quality of qualitative research studies. International Journal of Social Research Methodology, 7, 181–196.

    Google Scholar 

  • Macha, T., & Petermann, F. (2008). The ET 6-6: A method for development assessment for German-speaking countries. Journal of Psychology, 216, 154–160.

    Google Scholar 

  • *Majnemer, A., Limperopoulos, C., Shevell, M., Rohlicek, C., Rosenblatt, B., & Tchervenkov, C. (2006). Health and well-being of children with congenital cardiac malformations, and their families, following open-heart surgery. Cardiology in the Young, 16, 157–164.

    PubMed  Google Scholar 

  • *Majnemer, A., Limperopoulos, C., Shevell, M., Rohucek, C., Rosenblatt, B., & Tchervenkov, C. (2008). Developmental and functional outcomes at school entry in children with congenital heart defects. The Journal of Pediatrics, 153, 55–60.

    PubMed  Google Scholar 

  • Majnemer, A., Limperopoulos, C., Shevell, M. I., Rohlicek, C., Rosenblatt, B., & Tchervenkov, C. (2009). A new look at outcomes of infants with congenital heart disease. Pediatric Neurology, 40, 197–204.

    PubMed  Google Scholar 

  • Marino, B. S., Lipkin, P. H., Newburger, J. W., Peacock, G., Gerdes, M., Gaynor, J. W., … Mahle, W. T. (2012). Neurodevelopmental outcomes in children with congenital heart disease: evaluation and management: A scientific statement from the American Heart Association. Circulation, 126, 1143–1172.

    PubMed  Google Scholar 

  • *McCusker, C. G., Doherty, N. N., Molloy, B., Casey, F., Rooney, N., Mulholland, C., … Stewart, M. (2007). Determinants of neuropsychological and behavioural outcomes in early childhood survivors of congenital heart disease. Archives of Disease in Childhood, 92, 137–141.

    CAS  PubMed  Google Scholar 

  • Meiser-Stedman, R., Smith, P., Glucksman, W., Yule, W., & Dalgleish, T. (2008). The posttraumatic stress disorder diagnosis in preschool and elementary school-age children exposed to motor vehicle accidents. The American Journal of Psychiatry, 165, 1326–1337.

    PubMed  Google Scholar 

  • Miatton, M., De Wolf, D., Francois, K., Thiery, E., & Vingerhoets, G. (2007). Behavior and self-perception in children with a surgically corrected congenital heart disease. Developmental and Behavioral Pediatrics, 28, 294–301.

    Google Scholar 

  • Moher, D., Liberati, A., Tetzlaff, J., & Altman, D. G. (2009). Preferred reporting systems for systematic reviews and meta-analyses: The PRISMA statement. Open Medicine, 3, e123–e130.

    PubMed  PubMed Central  Google Scholar 

  • Mussatto, K., Hollenbeck-Pringle, D., Trachtenberg, F., Sood, E., Sananes, R., Pike, N. A., … Pemberton, V. L. (2018). Utilisation of early intervention services in young children with hypoplastic left heart syndrome. Cardiology in the Young, 28, 126–133.

    PubMed  Google Scholar 

  • Mussatto, K. A., Hoffmann, R. G., Hoffman, G., Tweddell, J. S., Bear, L., Cao, Y., & Brosig, C. L. (2014). Risk and prevalence of developmental delay in young children with congenital heart disease. Pediatrics, 133, 570–577.

    Google Scholar 

  • Papousek, M. (2011). Resilience, strengths, and regulatory capacities: Hidden resources in developmental disorders of infant mental health. Infant Mental Health Journal, 32, 29–46.

    PubMed  Google Scholar 

  • Pinquart, M., & Shen, Y. (2011). Behavior problems in children and adolescents with chronic physical illness: A meta-analysis. Journal of Pediatric Psychology, 36, 1003–1016.

    PubMed  Google Scholar 

  • *Re, J. M., Dean, S., Mullaert, J., Guedeney, A., & Menahem, S. (2018). Maternal distress and infant social withdrawal (ADBB) following infant cardiac surgery for congenital heart disease. World Journal for Pediatric and Congenital Heart Surgery, 9, 624–637.

    PubMed  Google Scholar 

  • Ringle, M. L., & Wernovsky, G. (2016). Functional, quality of life, and neurodevelopmental outcomes after congenital cardiac surgery. Seminars in Perinatology, 40, 556–570.

    PubMed  Google Scholar 

  • *Sadhwani, A., Asaro, L. A., Goldberg, C., Ware, J., Butcher, J., Gaies, M., … Agus, M. S. D. (2016). Impact of tight glycaemic control on neurodevelopmental outcomes at 1 year of age for children with congenital heart disease: A randomized controlled trial. The Journal of Pediatrics, 174, 193–198.

    PubMed  PubMed Central  Google Scholar 

  • *Sarajuuri, A., Jokinen, E., Mildh, L., Tujulin, A., Mattila, I., Valanne, L., & Lonnqvist, T. (2012). Neurodevelopmental burden at age 5 years in patients with univentricular heart. Pediatrics, 130, e1636–e1646.

    PubMed  Google Scholar 

  • Schore, A. N. (2001). Effects of a secure attachment relationship on right brain development, affect regulation and infant mental health. Infant Mental Health Journal, 22, 7–66.

    Google Scholar 

  • *Seltzer, L., Swartz, M. F., Kwon, J., Burchfiel, J., Cholette, J. M., Wang, H., … Alfieris, G. M. (2016). Neurodevelopmental outcomes after neonatal cardiac surgery: Roles of cortical isoelectric activity. The Journal of Thoracic and Cardiovascular Surgery, 151, 1137–1144.

    PubMed  Google Scholar 

  • Shonkoff, J., & Phillips, D. (Eds.). (2000). From neurons to neighbourhoods: The science of early childhood development. Washington, DC: National Academy Press.

    Google Scholar 

  • Snookes, S. H., Gunn, J. K., Eldridge, B. J., Donath, S. M., Hunt, R. W., Galea, M. P., & Shekerdemian, L. (2010). A systematic review of motor and cognitive outcomes after early surgery for congenital heart disease. Pediatrics, 125, e818–e827.

    PubMed  Google Scholar 

  • Sparrow, S. S., Cicchetti, D. V., & Balla, D. A. (2005). Vineland-II adaptive behavior scales: Survey forms manual. Circle Pines: AGS Publishing.

    Google Scholar 

  • Stene-Larsen, K., Brandlistuen, R. E., Holmstrøm, H., Landolt, M. A., Eskedal, L. T., Engdahl, B., & Vollrath, M. E. (2011). Longitudinal findings from a Norwegian case-cohort study on internalizing problems in children with congenital heart defects. Acta Paediatrica, 100, 236–241.

    PubMed  Google Scholar 

  • *Sterken, C., Lemiere, J., Van der Berghe, G., & Mesotten, D. (2016). Neurocognitive development after pediatric heart surgery. Pediatrics, 137, e20154675.

    PubMed  Google Scholar 

  • *Tahirovic, E., Begic, H., Tahirovic, J., & Varni, J. W. (2011). Quality of life in children after cardiac surgery for congenital heart disease. Collegium Antropologicum, 35, 1285–1290.

    PubMed  Google Scholar 

  • Torowicz, D., Irving, S., Hanlon, A., Sumpter, D., & Medoff-Cooper, B. (2010). Infant temperament and parental stress in 3-month-old infants after surgery for complex congenital heart disease. Journal of Developmental and Behavioral Pediatrics, 31, 202–208.

    PubMed  PubMed Central  Google Scholar 

  • van der Linde, D., Konings, E. E. M., Slager, M. A., Witsenburg, M., Helbing, W. A., Takkenberg, J. J. M., & Roos-Hesselink, J. W. (2011). Birth prevalence of congenital heart disease worldwide: A systematic review and meta-analysis. Journal of the American College of Cardiology, 58, 2241–2247.

    PubMed  Google Scholar 

  • Varni, J. W., & Limbers, C. A. (2009). The Pediatric Quality of Life Inventory: Measuring pediatric health-related quality of life from the perspective of children and their parents. Pediatric Clinics of North America, 56, 843–863.

    PubMed  Google Scholar 

  • *Vedovelli, L., Padalino, M., Suppiej, A., Sartori, S., Falasco, G., Simonato, M., … Cogo, P. (2018). Cardiopulmonary-bypass glial fibrillary acidic protein correlates with neurocognitive skills. The Annals of Thoracic Surgery, 106, 792–798.

    PubMed  Google Scholar 

  • *Visconti, K. J., Saudino, K. J., Rappaport, L. A., Newburger, J. W., & Bellinger, D. C. (2002). Influence of parental stress and social support on the behavioral adjustment of children with transposition of the great arteries. Developmental and Behavioral Pediatrics, 23, 314–321.

    Google Scholar 

  • Viswanathan, M., Ansari, M. T., Berkman, N. D., Chang, S., Hartling, L., McPheeters, L. M., … Treadwell, J. R. (2012). Assessing the risk of bias of individual studies in systematic reviews of health care interventions. In: Agency for Healthcare Research and Quality Methods Guide for Comparative Effectiveness Reviews. March 2012. AHRQ Publication No. 12-EHC047-EF. Retrieved July 11, 2019, from www.effectivehealthcare.ahrq.gov/.

  • *Werner, H., Latal, B., Buechel, E. V., Beck, I., & Landolt, M. (2014). Health-related quality of life after open-heart surgery. The Journal of Pediatrics, 164, 254–258.

    PubMed  Google Scholar 

  • Wernovsky, G. (2006). Current insights regarding neurological and developmental abnormalities in children and young adults with complex congenital cardiac disease. Cardiology in the Young, 16, 92–104.

    PubMed  Google Scholar 

  • Woolf, C., Muscara, F., Anderson, V. A., & McCarthy, M. C. (2015). Early traumatic stress responses in parents following a serious illness in their child: A systematic review. Journal of Clinical Psychology in Medical Settings, 22, 53–66.

    Google Scholar 

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Acknowledgements

The research project reported in this published work was conducted by the authors as part of their Doctorate in Pediatrics at the University of Melbourne, or employment with the Murdoch Children’s Research Institute, or The Royal Children’s Hospital, Melbourne, Australia. No funding support was received for this project. The authors have full control of all primary data and agree to allow the journal of publication to review the data if requested.

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Clancy, T., Jordan, B., de Weerth, C. et al. Early Emotional, Behavioural and Social Development of Infants and Young Children with Congenital Heart Disease: A Systematic Review. J Clin Psychol Med Settings 27, 686–703 (2020). https://doi.org/10.1007/s10880-019-09651-1

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