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ECG contamination of EEG signals: effect on entropy

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Abstract

Entropy™ is a proprietary algorithm which uses spectral entropy analysis of electroencephalographic (EEG) signals to produce indices which are used as a measure of depth of hypnosis. We describe a report of electrocardiographic (ECG) contamination of EEG signals leading to fluctuating erroneous Entropy values. An explanation is provided for mechanism behind this observation by describing the spread of ECG signals in head and neck and its influence on EEG/Entropy by correlating the observation with the published Entropy algorithm. While the Entropy algorithm has been well conceived, there are still instances in which it can produce erroneous values. Such erroneous values and their cause may be identified by close scrutiny of the EEG waveform if Entropy values seem out of sync with that expected at given anaesthetic levels.

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References

  1. Prabhakar H, Ali Z, Bithal PK, Singh GP, Laithangbam PK, Dash HH. EEG entropy values during isoflurane, sevoflurane and halothane anesthesia with and without nitrous oxide. J Neurosurg Anesthesiol. 2009;21:108–11.

    Article  PubMed  Google Scholar 

  2. Hakomäki M. ECG artefacts in EEG measurements. Master of Science thesis, Tampere University of Technology, Tampere; 2013.

  3. Viertiö-Oja H, Maja V, Särkelä M, Talja P, Tenkanen N, Tolvanen-Laakso H, Paloheimo M, Vakkuri A, Yli-Hankala A, Meriläinen P. Description of the entropy algorithm as applied in the Datex-Ohmeda S/5 Entropy Module. Acta Anaesthesiol Scand. 2004;48:154–61.

    Article  PubMed  Google Scholar 

  4. Murthy VK, Grove TM, Harvey GA, Haywood LJ. Clinical usefulness of ECG frequency spectrum analysis. In: Computer application in medical care. Proceedings of the second annual symposium 1978; pp. 610–12.

  5. Clifford GD. ECG statistics, noise, artifacts, and missing data. In: Clifford GD, Azuaje F, McSharry PE (eds) Advanced methods for ECG analysis. London: Artech House 2006; pp. 55–99.

  6. Rampil IJ. A primer for EEG signal processing in anesthesia. Anesthesiology. 1998;89:980–1002.

    Article  CAS  PubMed  Google Scholar 

  7. Gugino LD, Chabot RJ, Prichep LS, John ER, Formanek V, Aglio LS. Quantitative EEG changes associated with loss and return of consciousness in healthy adult volunteers anaesthetized with propofol or sevoflurane. Br J Anaesth. 2001;87:421–8.

    Article  CAS  PubMed  Google Scholar 

  8. Kishimoto T, Kadoya C, Sneyd R, Samra SK, Domino EF. Topographic electroencephalogram of propofol-induced conscious sedation. Clin Pharmacol Ther. 1995;58:666–74.

    Article  CAS  PubMed  Google Scholar 

  9. Kochs E, Bischoff P, Pichlmeier U, Schulte am Esch J. Surgical stimulation induces changes in brain electrical activity during isoflurane/nitrous oxide anesthesia. A topographic electroencephalographic analysis. Anesthesiology. 1994;80:1026–34.

    Article  CAS  PubMed  Google Scholar 

  10. Kamath C. Quantification of electrocardiogram rhythmicity to detect life threatening cardiac arrhythmias using spectral entropy. J Eng Sci Technol. 2013;8:588–602.

    Google Scholar 

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Correspondence to Dhritiman Chakrabarti.

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Chakrabarti, D., Bansal, S. ECG contamination of EEG signals: effect on entropy. J Clin Monit Comput 30, 119–122 (2016). https://doi.org/10.1007/s10877-015-9694-7

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  • DOI: https://doi.org/10.1007/s10877-015-9694-7

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