Skip to main content
SpringerLink
Log in

Synthesis of E Isomer and Crystal Structures of E and Z Isomers of 3-(2,5-Dimethoxyphenyl)-2-(4-methoxyphenyl)acrylonitrile

  • Original Paper
  • Published:
Journal of Chemical Crystallography Aims and scope Submit manuscript

Abstract

Details of the synthesis of the E isomer of 3-(2,5-dimethoxyphenyl)-2-(4-methoxyphenyl)acrylonitrile, and the X-ray crystal structures of both the E and Z isomers of this compound are presented. The E isomer crystallizes in the P21/c space group with cell parameters, a = 8.5659(17) Å, b = 16.399(3) Å, c = 11.224(2) Å, α = 90°, β = 95.27(3)°, γ = 90°and Z = 4. The Z isomer crystallizes in the Pca21 space group with cell parameters, a = 4.1223(8) Å, b = 19.113(4) Å, c = 19.453(4) Å, α = 90°, β = 90°, γ = 90° and Z = 4.

Index Abstract

Synthesis of E isomer and X-ray crystal structure determination of both E and Z isomers of 3-(2,5-dimethoxyphenyl)-2-(4-methoxyphenyl)acrylonitrile are presented.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Scheme 1
Fig. 2
Fig. 3
Fig. 4

Similar content being viewed by others

References

  1. Cossart P, Jonquie`res R (2000) Proc Natl Acad Sci USA 97:5013

    Article  CAS  Google Scholar 

  2. Navarre WW, Schneewind O (1999) Microbiol Mol Biol Rev 63:174

    CAS  Google Scholar 

  3. Supuran CT, Scozzafava A, Clare BW (2002) Med Res Rev 22:329

    Article  CAS  Google Scholar 

  4. Schneewind O, Fowler A, Faull KF (1995) Science 268:103

    Article  CAS  Google Scholar 

  5. Ton-That H, Faull KF, Schneewind O (1997) J Biol Chem 272:22285

    Article  CAS  Google Scholar 

  6. Jonsson IM, Mazmanian SK, Schneewind O, Bremell T, Tarkowski A (2003) Microbes Infect 5:775

    Article  CAS  Google Scholar 

  7. Jonsson IM, Mazmanian SK, Schneewind O, Verdrengh M, Bremell T, Tarkowski AJ (2002) Infect Dis 185:1417

    Article  CAS  Google Scholar 

  8. Zong Y, Bice T, Ton-That H, Schneewind O, Narayana SVL (2004) J Biol Chem 279:31383

    Article  CAS  Google Scholar 

  9. Oh KB, Kim SH, Lee J, Cho WJ, Lee T, Kim S (2004) J Med Chem 47:2418

    Article  CAS  Google Scholar 

  10. Chenna BC, Shinkre BA, Patel S, Owens SB, Gray GM, Velu SE (2006) J Chem Crystallogr. doi: 10.1007/s10870-007-9288-4

    Google Scholar 

  11. CAD4 -PC ver. 1.2; Enraf Nonius :Delft, The Netherlands, 1988

  12. Sheldrick GM (2001) SHELXTL NT Ver. 6.12. Bruker AXS, Madison, WI

    Google Scholar 

  13. Thewalt J, Bugg CE (1972) Acta Cryst B28:871

    Google Scholar 

  14. Burnett MN, Johnson CK (1996) ORTEP-III: oak ridge thermal ellipsoid plot program for crystal structure illustrations, Oak Ridge National Laboratory Report ORNL-6895

Download references

Author information

Authors and Affiliations

  1. Department of Chemistry, University of Alabama at Birmingham, 901, 14th Street South, Birmingham, AL, 35294-1240, USA

    Bidhan A. Shinkre, Dwayaja H. Nadkarni, Samuel B. Owens Jr., Gary M. Gray & Sadanandan E. Velu

Authors
  1. Bidhan A. Shinkre
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Dwayaja H. Nadkarni
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Samuel B. Owens Jr.
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Gary M. Gray
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Sadanandan E. Velu
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Sadanandan E. Velu.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Shinkre, B.A., Nadkarni, D.H., Owens, S.B. et al. Synthesis of E Isomer and Crystal Structures of E and Z Isomers of 3-(2,5-Dimethoxyphenyl)-2-(4-methoxyphenyl)acrylonitrile. J Chem Crystallogr 38, 205–209 (2008). https://doi.org/10.1007/s10870-007-9290-x

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10870-007-9290-x

Keywords

Search

Navigation