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Synthesis and Crystal Structure of Tert-butyl 2-((phenylthio)-carbonyl)pyrrolidine-1-carboxylate

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Abstract

Tert-butyl 2-((phenylthio)carbonyl)pyrrolidine-1-carboxylate, was synthesized by using iso-butoxycarbonyl chloride (i-BuOCOCl) via mixed anhydride method. The obtained product was characterized spectroscopically and finally confirmed by X-ray diffraction studies. The title compound C16 H21 N O3 S crystallizes in the triclinic space group P1 with the cell parameters a = 6.0250(7) Å, b = 8.2820(13) Å, c = 8.7700(14) Å, α = 102.352(4)°, β = 102.993(11)°, γ = 90.279(8)°, V = 415.89(10) Å3 and Z = 1. The proline ring in the structure is in a envelope conformation. The structure exhibits intermolecular hydrogen bonds of the type C–H...O.

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Notes

  1. CCDC 613082 contains the supplementary crystallographic data for this paper. These data can be obtained free of charge via www.ccdc.cam.ac.uk/conts/retrieving.html (or from The Cambridge Crystallographic Data Centre, 12 Union Road, Cambridge CB2 1EZ, UK; fax: +44(0)1223-336033.

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Acknowledgements

The authors would like to express their thanks to DST, Government of India for financial assistance under the project SP/I2/FOO/93.

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Authors and Affiliations

  1. Department of Studies in Physics, University of Mysore, Manasagangotri, Mysore, 570 006, India

    S. Naveen, M. A. Sridhar & J. Shashidhara Prasad

  2. Department of Studies in Chemistry, University of Mysore, Mysore, 570 006, India

    B. Dinesh, K. Abiraj & D. Channe Gowda

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  1. S. Naveen
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  2. B. Dinesh
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Correspondence to M. A. Sridhar.

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Naveen, S., Dinesh, B., Abiraj, K. et al. Synthesis and Crystal Structure of Tert-butyl 2-((phenylthio)-carbonyl)pyrrolidine-1-carboxylate. J Chem Crystallogr 37, 721–725 (2007). https://doi.org/10.1007/s10870-007-9239-0

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