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Cell/surface interactions and adhesion on bioactive glass 45S5

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Abstract

This paper examines the effects of surface texture (smooth versus rough) on cell/surface interactions on the bioactive glass, 45S5. The cell surface interactions associated with cell spreading are studied using cell culture experiments. Subsequent energy dispersive x-ray spectroscopy is also used to reveal the distributions of calcium, phosphorous, sodium and oxygen on the surfaces of the bioactive glasses. The implications of the results are then discussed for the applications of textured bioactive glasses in medicine.

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Authors and Affiliations

  1. Princeton Institute of Science and Technology of Materials, Princeton, NJ

    S. Levy, M. Van Dalen, S. Agonafer & W. O. Soboyejo

  2. The Department of Mechanical and Aerospace Engineering, Princeton University, Princeton, NJ, 08544

    S. Levy, M. Van Dalen & W. O. Soboyejo

  3. The Department of Chemical Engineering, Princeton University, Princeton, NJ, 08544

    S. Agonafer

Authors
  1. S. Levy
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  2. M. Van Dalen
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  3. S. Agonafer
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  4. W. O. Soboyejo
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Correspondence to W. O. Soboyejo.

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Levy, S., Van Dalen, M., Agonafer, S. et al. Cell/surface interactions and adhesion on bioactive glass 45S5. J Mater Sci: Mater Med 18, 89–102 (2007). https://doi.org/10.1007/s10856-006-0666-9

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  • DOI: https://doi.org/10.1007/s10856-006-0666-9

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