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Electrochemical detection of dopamine using van der waals-interacted NiO–ZnO-functionalized reduced graphene oxide nanocomposite

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Abstract

The in situ Nickel oxide-zinc oxide-doped reduced graphene oxide (NiO–ZnO/rGO) nanocomposite is synthesized by the hydrothermal method. NiO–ZnO/rGO nanocomposite-modified glassy carbon electrode (GCE) utilized as electrochemical sensor for dopamine sensing. Scanning electron microscopy (SEM), RAMAN spectroscopy, Transmission electron microscopy (TEM), X-ray diffraction (XRD), and X-ray photoelectron spectroscopy (XPS) were used for morphological and structural characterizations of NiO–ZnO/rGO nanocomposite. Further investigation of the redox response and the charge transfer characteristics of dopamine (DA) at NiO–ZnO/rGO-modified GCE tested using cyclic voltammetry and electrochemical impedance spectroscopy. The prepared GCE nanocomposite-modified electrochemical sensor show a linear response of redox peak current for DA in the concentration range of 0.0041–0.054 µM. The active electrochemical surface area of the sensor found to be 2.1 × 10−6 cm2, with low detection limit of 0.0076 µM and high sensitivity of 12.19 µA L cm−2 Mol−1. The constructed sensor has close to 100% recovery toward DA in voluntarily collected human urine samples. The composite exhibits good reproducibility for sensing DA for month, which is an indication of their repeatability. Also designed sensors show 123% retention current to 100 cycles of CV indicates the good stability of the sensor to DA, which are crucial for the fabrication of further devices.

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Authors and Affiliations

  1. Department of chemistry, Rajarshi Chhatrapati Shahu College, Kolhapur, Maharashtra, 416004, India

    Ganesh K. Chougule & Kishor V. Gaikwad

  2. School of Nanoscience and technology, Shivaji University, Kolhapur, Maharashtra, 416004, India

    Anita K. Tawade & Kiran Kumar K. Sharma

  3. Department of Chemistry, Shivaji University, Kolhapur, Maharashtra, 416004, India

    Jayashri V. Kamble & Shivaji N. Tayade

  4. Department of Advanced Chemical Engineering, Chonnam National University, Gwangju, 61186, South Korea

    Sawanta S. Mali & Chang Kook Hong

  5. Department of Chemistry, Walchand College of Engineering, Sangli, Maharashtra, 416415, India

    Anil A. Powar

Authors
  1. Ganesh K. Chougule
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Contributions

SNT conceptualized the synthesis method. GKC optimized and synthesized the NiO–ZnO/rGO composite materials under supervision of SNT and KVG. JVK, AAP and GKC characterized all the samples and also SSM and CKH characterized all the samples. AKT and GKC performed the electrochemical experiments in supervision of SNT and KKS. SNT supervised the overall research. All authors discussed and wrote the manuscript for final communication.

Corresponding authors

Correspondence to Kishor V. Gaikwad or Shivaji N. Tayade.

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Chougule, G.K., Tawade, A.K., Kamble, J.V. et al. Electrochemical detection of dopamine using van der waals-interacted NiO–ZnO-functionalized reduced graphene oxide nanocomposite. J Mater Sci: Mater Electron 35, 301 (2024). https://doi.org/10.1007/s10854-024-11950-9

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