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Scaffolds modified with graphene as future implants for nasal cartilage

  • Materials for life sciences
  • Published:
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Abstract

In this study, a 3D printing process was used to fabricate antibacterial polycaprolactone/graphene scaffolds using short filament sticks. The first part of the work focused on the manufacture of a strong and flexible filament, in the form of sticks for use in the existing FDM system without any hardware or software modification. New filament materials, which can be connected together, containing graphene nanoplatelets have been prepared at three levels of concentration: 0.5, 5 and 10 wt%. The PCL and graphene were processed into filaments using injection molding, and their morphology, FTIR, WAXS, ultrasonic wave propagation, and mechanical properties were measured. WAXS and ultrasonic tests confirmed the even distribution of graphene powder in the sample modified with 0.5 wt% of graphene. The presence of graphene in the samples improved their mechanical properties; however, 10 wt% of addition did not produce further tensile strength enhancement. The filaments were successfully tested in a commercially available 3D printer to evaluate their capacity to produce printed scaffolds for nasal cartilage replacement. Initial cell culture study has shown that printed scaffolds support the proliferation of chondrocytes.

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Data availability

The raw/processed data required to reproduce these findings cannot be shared at this time due to technical or time limitations.

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Acknowledgements

This work was supported by the National Science Centre, Poland in the framework of the project: “Layered scaffolds for nasal cartilages reconstruction fabricated by 3D printing and electrospinning” 2015/18/E/ST5/00189 (Sonata Bis 5).

Author information

Authors and Affiliations

  1. Division of Materials Engineering, Department of Mechanical Engineering Fundamentals, ATH University of Bielsko-Biala, Bielsko-Biała, Poland

    Izabella Rajzer & Anna Kurowska

  2. Division of Mechatronics, Department of Mechanical Engineering Fundamentals, ATH University of Bielsko-Biala, Bielsko-Biała, Poland

    Adam Jabłoński, Jerzy Kopeć & Marcin Sidzina

  3. Institute of Textile Engineering and Polymer Materials, ATH University of Bielsko-Biala, Bielsko-Biała, Poland

    Ryszard Kwiatkowski

  4. Department of Biomaterials and Composites, Faculty of Materials Science and Ceramics, AGH University of Science and Technology, Kraków, Poland

    Wojciech Piekarczyk

  5. Faculty of Health Sciences, ATH University of Bielsko-Biala, Bielsko-Biała, Poland

    Maciej B. Hajduga

  6. Department of Cytobiology, UJ Jagiellonian University, Collegium Medicum, Kraków, Poland

    Elżbieta Menaszek

Authors
  1. Izabella Rajzer
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  2. Anna Kurowska
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Correspondence to Izabella Rajzer.

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Rajzer, I., Kurowska, A., Jabłoński, A. et al. Scaffolds modified with graphene as future implants for nasal cartilage. J Mater Sci 55, 4030–4042 (2020). https://doi.org/10.1007/s10853-019-04298-7

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  • DOI: https://doi.org/10.1007/s10853-019-04298-7

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