Abstract
To create novel materials of skin tissue engineering, the blends of tannin-grafted poly(ɛ-caprolactone) (TA-g-PCL) and poly(l-lactic acid) (PLLA) have been prepared by electrospinning, and their corresponding characteristics are evaluated such as morphology, FTIR, thermodynamics, mechanics, wettability, as well as biocompatibility. TA-g-PCL and PLLA can be well blended to make smooth fibers, and fibrous diameter turns thinner with blending TA-g-PCL. At 15 wt%, the fibrous membrane shows higher tensile strength and elongation at a break than the other samples due to its best crystallinity. Membranous wettability drops with blending TA-g-PCL, but it increases sharply after incorporating PF108. At the same time, PLLA/TA-g-PCL fiber membrane is biocompatible. The biodegradable PLLA/TA-g-PLLA membrane is a promising candidate as skin tissue engineering.
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Acknowledgements
This work was supported by the project of Science and Technology bureau of Changchun (Grant No. 14KG106); Education Department of Jilin (Grant No. 2014123); and the Natural Science Foundation of Jilin province (Grant No. 20130102065JC).
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Jiang, S., Song, P., Guo, H. et al. Blending PLLA/tannin-grafted PCL fiber membrane for skin tissue engineering. J Mater Sci 52, 1617–1624 (2017). https://doi.org/10.1007/s10853-016-0455-x
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DOI: https://doi.org/10.1007/s10853-016-0455-x