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Fabrication and characterization of polymethylmethacrylate/polysulphone/β-tricalcium phosphate composite for orthopaedic applications

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Abstract

Polymethylmethacrylate (PMMA) and polysulphone (PSu) are biocompatible polymers and are used widely for biomedical applications. In this study, a blend membrane of PMMA/PSu was fabricated using methylene bisacrylamide (MBA) as the blending agent and its properties were studied. Subsequently, a composite membrane consisting of β-tricalcium phosphate (β-TCP) filler dispersed in a polymer matrix of PMMA/PSu was fabricated and evaluated for application as an orthopaedic prosthetic material. Fourier Transform Infrared Spectroscopy spectra of the blend confirmed the interaction of PMMA and PSu with the blending agent MBA. The X-ray diffraction analysis showed that PMMA/PSu membranes exhibited a higher degree of crystallinity when compared with that of the individual polymers. The thermal properties of the samples studied by thermogravimetric analysis showed an increase in the thermal stability of the PMMA/PSu when compared with individual PMMA and PSu membranes. The morphology of the composite samples analysed through SEM showed that the fillers were widely distributed and agglomerated at certain places. The tensile strength of the PMMA/PSu/β-TCP was found to be inferior to that of PMMA/β-TCP although much superior to that of PSu/β-TCP composite membranes. Hardness testing performed using durometer hardness tester (Shore D) showed that the PMMA/PSu/β-TCP samples exhibited higher hardness than the composites having individual PMMA and PSu matrices. Analysis of the optical properties of the polymer membranes suggested good blend formation between PMMA and PSu. The in vitro bioactivity study suggested that the density of the calcium phosphate layer formed on the surface of PMMA/PSu/β-TCP was much higher than that of composites made of either PMMA or PSu matrix. The results of the study showed that the blended composite membranes exhibited favourable properties for biomedical applications such as for orthopaedic prostheses.

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References

  1. Frazer RQ, Byron RT, Osborne PB, West KP (2005) J Long Term Eff Med Implants 15(6):629

    CAS  Google Scholar 

  2. Park JB (1992) Ann Biomed Eng 20(6):583

    Article  CAS  Google Scholar 

  3. Arias JL, Carrillo AN, Arias JI, Escobar C, Bodero M, David M, Fernández MS (2004) J Mater Chem 14:2154

    Article  CAS  Google Scholar 

  4. Nakashima A, Ogata S, Doi S, Yamahira M, Naraki S, Takasugi N, Ohmoto T, Ito T, Masaki T, Yorioka N (2006) Clin Exp Nephrol 10(3):210

    Article  Google Scholar 

  5. Lu J (2004) Orthopedic bone cements. In: Poitout DG (ed) Biomechanics and biomaterials in orthopaedics, 1st edn. Springer, Singapore, p 86

    Google Scholar 

  6. Tsukeoka T, Suzuki M, Ohtsuki C, Sugino A, Tsuneizumi Y, Miyagi J, Kuramoto K, Moriya H (2006) Biomaterials 27(21):3897

    Article  CAS  Google Scholar 

  7. Harper EJ (1998) Proc Inst Mech Eng H 212(2):113

    CAS  Google Scholar 

  8. Kokubo T (2005) Mater Sci Eng C 25:97

    Article  Google Scholar 

  9. Moszner N, Fischer UK, Angermann J, Rheinberger V (2006) Dent Materials 22:1157

    Article  CAS  Google Scholar 

  10. Kratz K, Lapp A, Eimer W, Hellweg T (2002) Colloids Surf A Physicochem Eng Asp 197:55

    Article  CAS  Google Scholar 

  11. Deimede VA, Fragou KV, Koulouri EG, Kallitsis JK, Voyiatzis GA (2000) Polymer 41:9095

    Article  CAS  Google Scholar 

  12. Lemons JE (1996) Bone 19(Suppl 1):121S

    Article  CAS  Google Scholar 

  13. Sunder M, Babu NR, Victor SP, Kumar KR, Kumar TSS (2005) Trends Biomater Artif Organs 18(2):213

    Google Scholar 

  14. Kokubo T, Kushitani H, Sakka S, Kitsugi T, Yamamuto T (1990) J Biomed Mater Res 24:721

    Article  CAS  Google Scholar 

  15. Helebrant A, Jonášová L, Šanda L (2002) Ceram Silik 46(1):9

    CAS  Google Scholar 

  16. Bayraktar D, Tas AC (2000) Turk J Med Sci 30:235

    CAS  Google Scholar 

  17. Li XW, Yasuda HY, Umakoshi Y (2006) J Mater Sci Mater Med 17:73

    CAS  Google Scholar 

  18. Krause S (1986) Pure Appl Chem 58(12):1553

    Article  CAS  Google Scholar 

  19. Rajulu AV, Reddy RL, Raghavendra SM, Ahmed SA (1999) Eur Polym J 35:1183

    Article  CAS  Google Scholar 

  20. Cascone MG, Polacco G, Lazzeri L, Barbani N (1997) J Appl Polym Sci 66:2089

    Article  CAS  Google Scholar 

  21. Rajulu AV, Devi LG, Rao GB (2003) J Appl Polym Sci 89:2970. doi:10.1002/app.12399

    Article  CAS  Google Scholar 

  22. Stein RS, Keane JJ, Norris FH, Bettelheim FA, Wilson PR (1959) Ann N Y Acad Sci 83:37. doi:10.1111/j.1749-6632.1960.tb40882.x

    Article  CAS  Google Scholar 

  23. Pattanayak DK, Divya P, Upadhyay S, Prasad RC, Rao BT, Mohan TRR (2005) Trends Biomater Artif Organs 18(2):87

    Google Scholar 

  24. Tardei C, Grigore F, Pasuk I, Stoleriu S (2006) J Optoelectron Adv Mater 8(2):568

    CAS  Google Scholar 

  25. Mano JF, Sousa RA, Boesel LF, Neves NM (2004) Compos Sci Technol 64:789

    Article  CAS  Google Scholar 

  26. Wang M, Yue CY, Chua B (2001) J Mater Sci Mater Med 12:821

    Article  CAS  Google Scholar 

  27. Wang M (2003) Biomaterials 24:2133

    Article  CAS  Google Scholar 

Download references

Acknowledgement

The authors would like to acknowledge the National Doctoral Fellowship of All India Council for Technical Education (AICTE), New Delhi, India vide their letter no. 200-64/FIN/04/05/116, Dated 08.10.2010.

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  1. Department of Chemistry, Anna University, Guindy, Chennai, 600 025, India

    Kalambettu Aravind Bhat, Padmavathi Rajangam & Sangeetha Dharmalingam

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  1. Kalambettu Aravind Bhat
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  2. Padmavathi Rajangam
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  3. Sangeetha Dharmalingam
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Correspondence to Sangeetha Dharmalingam.

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Bhat, K.A., Rajangam, P. & Dharmalingam, S. Fabrication and characterization of polymethylmethacrylate/polysulphone/β-tricalcium phosphate composite for orthopaedic applications. J Mater Sci 47, 1038–1045 (2012). https://doi.org/10.1007/s10853-011-5892-y

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