Abstract
Cryopreservation, for many reasons, has assumed a central role in IVF treatment cycles, which has resulted in rapidly expanding cryopreserved oocyte and embryo inventory of IVF clinics. We aspire to consider how and with what resources and tools “deep” technology can offer solutions to these cryobiology programs. “Deep tech” has been applied as a global term to encompass the most advanced application of big data analysis for the most informed construction of algorithms and most sophisticated instrument design, utilizing, when appropriate and possible, models of automation and robotics to realize all opportunities for highest efficacy, efficiency, and consistency in a process.
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Shapiro BS, Daneshmand ST, Garner FC, Aguirre M, Hudson C, Thomas S. Evidence of impaired endometrial receptivity after ovarian stimulation for in vitro fertilization: a prospective randomized trial comparing fresh and frozen–thawed embryo transfer in normal responders. Fertility Sterility. 2011;96(2):344–8.
Maktoubian J, Ansari K. An IoT architecture for preventive maintenance of medical devices in healthcare organizations. Health Technol. 2019;9(3):233–43.
Jelacic S, Bowdle A, Nair BG, Kusulos D, Bower L, Togashi K. A system for anesthesia drug administration using barcode technology: the Codonics Safe Label System and Smart Anesthesia Manager™. Anesthesia Analgesia. 2015;121(2):410–21.
He W, Tan EL, Lee EW, Li TY. A solution for integrated track and trace in supply chain based on RFID & GPS. In2009 IEEE conference on emerging technologies & factory automation 2009 Sep 22 (pp. 1-6). IEEE.
Pomeroy KO, Marcon M. Reproductive tissue storage: quality control and management/inventory software. In Seminars in reproductive medicine 2018 Sep (Vol. 36, No. 05, pp. 280-288). Thieme Medical Publishers.
Palmer GA, Kratka C, Szvetecz S, Fiser G, Fiser S, Sanders C, Tomkin G, Szvetecz MA, Cohen J. Comparison of 36 assisted reproduction laboratories monitoring environmental conditions and instrument parameters using the same quality-control application. Reprod BioMed Online. 2019;39(1):63–74.
Moss SJ, Johnson WT. Automatic liquid nitrogen filling system. Rev Sci Instr. 1964;35(7):909–10.
Fahle S, Prinz C, Kuhlenkötter B. Systematic review on machine learning (ML) methods for manufacturing processes–identifying artificial intelligence (AI) methods for field application. Procedia CIRP. 2020;93:413–8.
McCall SJ, Branton PA, Blanc VM, Dry SM, Gastier-Foster JM, Harrison JH, Jewell SD, Dash RC, Obeng RC, Rose J, Mateski DL. The College of American Pathologists Biorepository Accreditation Program: results from the first 5 years. Biopreserv Biobank. 2018;16(1):16–22.
McCulloh DH, Labella PA, McCaffrey C. Quality management in the IVF laboratory. In: Montag MH, Morbeck DE (eds). Principles of IVF laboratory practice: Optimizing performance and outcomes. Cambridge University Press. 2017
Rienzi L, Bariani F, Dalla Zorza M, Romano S, Scarica C, Maggiulli R, Costa AN, Ubaldi FM. Failure mode and effects analysis of witnessing protocols for ensuring traceability during IVF. Reprod BioMed Online. 2015;31(4):516–22.
Messerlian C, Gaskins AJ. Epidemiologic approaches for studying assisted reproductive technologies: design, methods, analysis, and interpretation. Curr Epidemiol Rep. 2017;4(2):124–32.
Sharp TA, Garbarini WN, Johnson CA, Watson A, Greenberg R, Go KJ. Initial validation of an automated cryostorage and inventory management system. Fertility Sterility. 2019;112(3):e116.
Swanson TD, Birur GC. NASA thermal control technologies for robotic spacecraft. Appl Thermal Eng. 2003;23(9):1055–65.
Ethics Committee of the American Society for Reproductive Medicine. Disposition of unclaimed embryos: an Ethics Committee opinion. Fertility Sterility. 2021;116(1):48–53.
Go KJ, Romanski PA, Bortoletto P, Patel JC, Srouji SS, Ginsburg ES (2023) Meeting the challenge of unclaimed cryopreserved embryos. Fertil Steril 119:15–20
Gilboa D, Bori L, Shapiro M, Pellicer A, Maor R, Delgado A, Seidman D, Meseguer M. An artificial intelligence (AI) deselection model for top-quality blastocysts: algorithmic analysis of morphokinetic features for aneuploidy may increase implantation rates. In Human reproduction 2022 Jul 1 (Vol. 37, pp. I322-I323). Great Clarendon St, Oxford OX2 6DP, England: Oxford Univ Press.
Diakiw SM, Hall JM, VerMilyea MD, Amin J, Aizpurua J, Giardini L, Briones YG, Lim AY, Dakka MA, Nguyen TV, Perugini D. Development of an artificial intelligence model for predicting the likelihood of human embryo euploidy based on blastocyst images from multiple imaging systems during IVF. Hum Reprod. 2022;37(8):1746–59
Delestro F, Nogueira D, Ferrer-Buitrago M, Boyer P, Chansel-Debordeaux L, Keppi B, Sanguinet P, Trebesses L, Scalici E, De La Fuente A, Gómez E. O-124 a new artificial intelligence (AI) system in the block: impact of clinical data on embryo selection using four different time-lapse incubators. Human Reprod. 2022;37(Supplement_1):deac105-024.
National Quality Forum (NQF). List of serious reportable events (aka SRE or “never events”). Available from: https://www.qualityforum.org/Topics/SREs/List_of_SREs.aspx. Accessed 20 Mar 2023
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Cynthia Hudson is an employee of TMRW Life Sciences, Inc. Kathryn J. Go, PhD., H.C.L.D., none.
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Go, K.J., Hudson, C. Deep technology for the optimization of cryostorage. J Assist Reprod Genet 40, 1829–1834 (2023). https://doi.org/10.1007/s10815-023-02814-y
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DOI: https://doi.org/10.1007/s10815-023-02814-y