A universal method using Raman spectroscopy for the quantitative determination of oxytetracycline in three water-based medicines was developed. Five calibration models based on different mathematical data processing, i.e., one-dimensional calibration (Beer–Lambert law, classical least squares, stepwise multiple linear regression) and multi-dimensional calibration (partial least squares and principal component regression), were compared. The most accurate quantitative determinations were achieved when a calibration model based on partial least squares using two principal components was used.
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References
Weng Li Yoon, Am. Pharm. Rev., 8, No. 5, 115–118 (2005).
L. Rago, World Health Organization's Viewpoint, SMI Conference Documentation, London (2004).
T. E. Elizarova, M. A. Morozova, and T. V. Pleteneva, Pharm. Chem. J., 45, No. 5, 302–305 (2011).
D. Pivonka, J. Chalmers, and P. Griffiths, Applications of Vibrational Spectroscopy in Pharmaceutical Research and Development, John Wiley & Sons, New York (2007), pp. 293–308.
S. A. Burikov, T. A. Dolenko, and D. M. Karpov, Opt. Spektrosk., 109, No. 2, 306–312 (2010).
O. V. Boyarkin, Role of Fermi Resonancesin Formation of IR Spectra of Vibrationally Highly Excited Polyatomic Molecules, Author’s Abstract of a Candidate Dissertation in Physical-Mathematical Sciences, L. Ya. Karpov Scientific-Research Physical-Chemical Institute (1991), pp. 7–8.
Guideline on the Use of Near Infrared Spectroscopy by the Pharmaceutical Industry and the Date Requirements for New Submissions and Variations, European Medicines Agency, London (2012), pp. 12–22.
A. P. Arzamastsev, N. P. Sadchikova, and A. V. Titova, Khim.-Farm. Zh., 42, No. 8, 47–51 (2008).
A. P. Arzamastsev, N. P. Sadchikova, and A. V. Titova, Vopr. Biol., Med. Farm. Khim., No. 1, 16–20 (2010).
O. Ye. Rodionova and A. L. Pomerantsev, Trends Anal. Chem., 29, No. 8, 795–803 (2010).
D. A. Vereskun, O. E. Rodionova, A. V. Titova, and N. P. Sadchikova, Vestn. Roszdravnadzora, No. 2, 62–66 (2016).
O. E. Rodionova and A. L. Pomerantsev, Usp. Khim., 75, No. 4, 302–321 (2006).
K. Sangrungruang, A. Chotchuang, and R. Ueno, Fish. Sci., 70, No. 3, 467–472 (2004).
GOST 31694-2012. Method for determination of residual content of tetracycline group antibiotics using high-performance liquid chromatography with a mass-spectrometric detector.
A. A. Komarov, E. S. Vylegzhanina, and A. N. Panin, Conjugate of Oxytetracycline with Bovine Serum Albumin for Immunochemical Method Assay of Oxytetracycline, RU Pat. 2,243,235 C1, Dec. 27, 2004; FIPS, Moscow (2004), pp. 3–7.
E. O. Vityukova, A. V. Egorova, S. V. Bel’tyukova, and E. V. Malinka, Visn. Odes. Nats. Univ., Khim., 9, Nos. 6–7, 97–106 (2004).
A. J. Bajwa, H. Nawaz, M. I. Majeed, A. I. Hussain, and M. Kashif, Spectrochim. Acta, Part A, 238, 118446 (2020).
L. Coic, P.-Y. Sacre, A. Dispas, E. Dumont, and E. Ziemons, Talanta, 2141, 120888 (2020).
S. Mazurek and R. Szostak, Vib. Spectrosc., 93, 57–64 (2017).
B. N. Tarasevich, IR Spectra of Major Classes of Organic Compounds. Handbook Materials [in Russian], MGU im. M. V. Lomonosova, Moscow (2012), pp. 4–31.
A. Kh. Kuptsov and G. N. Zhizhin, Raman and Infrared Fourier Absorption Spectra of Polymers. Handbook [in Russian], Fizmatlit, Moscow (2001), pp. 26–29.
A. Hoskuldsson, Prediction Methods in Science and Technology, Thor Publishing, Copenhagen (1996), pp. 112–154.
A. Hoskuldsson, J. Chemom., 2, 211–228 (1988).
R. A. Kellner, J.-M. Mermet, M. Otto, and H. M. Widmer, Analytical Chemistry, Wiley VCH, Weinheim (1998) [Russian translation, Mir, Moscow (2004), Vol. 2, pp. 416–567].
K. H. Esbensen, Multivariate Data Analysis: In Practice, 4th edn., Camo, Oslo (2000) [translated from English by O. Rodionova (Ed.), IPKhF RAN, Chernogolovka (2005), pp. 54–69].
S. de Jong, Chemom. Intell. Lab. Syst., 18, 251–263 (1993).
B. Li, A. J. Morris, and E. B. Martin, Chemom. Intell. Lab. Syst., 72, 21–26 (2004).
M. Hubert and K. Vanden Branden, J. Chemom., 17, No. 10, 537–549 (2003).
E. Vigneau, M. Devaux, M. Qannari, and P. Robert, J. Chemom., 11, No. 3, 239–249 (1997).
P. Geladi, Chemom. Intell. Lab. Syst., 60, Nos. 1–2, 211–224 (2002).
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Translated from Zhurnal Prikladnoi Spektroskopii, Vol. 88, No. 1, pp. 119–124, January–February, 2021.
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Khrushchev, A.Y., Akmaev, E.R., Bondarenko, V.O. et al. Quantitative Determination of Oxytetracycline in Water-Based Liquid Dosage Forms by Raman Spectroscopy. J Appl Spectrosc 88, 108–113 (2021). https://doi.org/10.1007/s10812-021-01147-x
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DOI: https://doi.org/10.1007/s10812-021-01147-x