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Assessment of cataract forming effect of diabetes in young adults by lens densitometer

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Abstract

Purpose

To investigate the effect of the diabetes on cataract formation by Pentacam Scheimpflug topography system.

Materials and methods

Thirty diabetic patients and thirty-five healthy control subjects were included in the study. Exclusion criteria were smoking, high refractive error, any systemic disease or drug usage associated with cataract formation and to have diabetic retinopathy. The duration of diabetes and HbA1c level were recorded. A comprehensive ophthalmologic examination was performed in all cases. Pentacam (Oculus, Wetzlar, Germany) three-dimensional lens densitometer module was used to measure density of anterior, nuclear and posterior lens regions.

Results

Mean age of group 1 and group 2 was 37.80 ± 5.51 years and 36.51 ± 3.77 years, respectively. There were not any difference between groups in the means of age and sex (P = .271; P = .700). The mean duration of diabetes in group 1 was 4.23 ± 3.71 years (6 months–10 year). The mean HbA1c level was 8.12 ± 2.07% (5.4–12.7%). Anterior, nuclear and posterior mean lens densitometry measurements were significantly higher in group 1 (diabetic group) than group 2 (control group) [(8.90 ± 0.59%; 8.05 ± 0.72% P =  < .001), (7.52 ± 0.31%; 7.00 ± 0.59% P =  < .001), (7.25 ± 0.31%; 6.90 ± 0.73% P = .006), respectively].

Conclusion

Diabetes may have cataractous effect in anterior, nuclear and posterior regions of the lens.

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Correspondence to Neslihan Bayraktar Bilen.

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“All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee (Ankara Numune Education and Research Hospital + E-16–971) and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.”

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Bayraktar Bilen, N., Sarıcaoğlu, M.S. Assessment of cataract forming effect of diabetes in young adults by lens densitometer. Int Ophthalmol 40, 3357–3362 (2020). https://doi.org/10.1007/s10792-020-01523-0

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  • DOI: https://doi.org/10.1007/s10792-020-01523-0

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