Abstract
Purpose
To investigate the value of color Doppler imaging (CDI) of orbital vasculature in the assessment of ocular involvement in patients with Behçet’s disease (BD) without clinical ophthalmologic abnormalities.
Methods
CDI of the orbital vessels were performed on 26 eyes of 13 patients who were diagnosed as having BD with ocular involvement (group 1), 65 eyes of 33 patients who had BD without ocular involvement (group 2) and 40 eyes of 20 healthy volunteers (group 3). Peak systolic (PSV) and end-diastolic (EDV) blood flow velocities and resistivity index (RI) measurements were obtained for the ophthalmic artery (OA) and central retinal artery (CRA). The mean velocity of the central retinal vein (CRV) was also measured.
Results
For the OA, PSV and EDVs were significantly lower and RIs were significantly higher in group 2 than in control subjects. In group 1, only the EDVs of OA were significantly lower than in healthy subjects. For the CRA, PSV and EDVs were significantly lower, and RIs were significantly higher in both BD groups than those in group 3. When group 1 and group 2 were compared, the differences between PSV, EDV and RI measurements for the CRA and OA were statistically insignificant. There was no significant difference in blood flow velocity of the CRV between the three groups.
Conclusion
Major hemodynamic changes were observed in the ophthalmic vasculature of Behçet’s patients with or without ocular involvement by CDI. CDI may detect ocular blood flow alterations before initial clinical manifestations.
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References
Suzuki KM, Suzuki N (2004) Behcet’s disease. Clin Exp Med 3:10–20
Tugal-Tutkun I, Onal S, Altan-Yaycioglu R, Altunbas HH, Urgancioglu M (2004) Uveitis in Behcet disease: an analysis of 880 patients. Am J Ophthalmol 138:373–380
Lieb WE, Cohen SM, Merton DA, Shields JA, Mitchell DG, Goldberg BB (1991) Color Doppler imaging of the eye and orbit. Technique and normal vascular anatomy. Arch Ophthalmol 109:527–531
Seckin D, Baysal K, Erkan D, Oltulu Y, Akpolat T, Turanli AY (1996) Ophthalmic and central retinal artery flow velocities in patients with Behcet’s disease. Eur J Ophthalmol 6:215–216
Ucakhan O, Salih M, Altan S, Ozdemir O (1997) Color Doppler ultrasound in ocular Behcet’s disease. Eur J Ophthalmol 7:258–261
Özdemir H, Atilla H, Atilla S, Işık S, Zilelioğlu G (1995) Diagnosis of ocular involvement in Behçet’s disease: value of spectral and color doppler sonography. Am J Roentgenol 164:1223–1227
Atilla H, Zilelioglu G, Ozdemir H, Atilla S, Isik S (1997) Color Doppler imaging in uveitis. Eur J Ophthalmol 7:92–100
Celebi S, Akfirat M, Celebi H, Alagoz G (2000) Color Doppler ultrasonography in ocular Behcet’s disease. Acta Ophthalmol Scand 78:30–33
Duranoglu Y, Apaydin C, Karaali K, Yucel I, Apaydin A (2001) Color Doppler imaging of the orbital vessels in Behcet’s disease. Ophthalmologica 215:8–15
Caca I, Nazaroglu H, Unlu K, Cakmak SS, Ari S, Sakalar YB (2004) Color Doppler imaging of ocular hemodynamic changes in Behcet’s disease. Jpn J Ophthalmol 48:101–105
Mullaney J, Collum LMT (1985) Ocular vasculitis in Behcet’s disease. A pathological and immunohistochemical study. Int Ophthalmol 7:183–191
Atmaca LS, Batioglu F (1999) Indocyanine green videoangiography and color Doppler imaging in Behcet’ disease. Acta Ophthalmol Scand 77:444–447
Taylor GA, Short BL, Walker LK, Traystman RJ (1990) Intracranial blood flow: quantification with duplex Doppler and color Doppler flow US. Radiology 176:231–236
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Isik, C., Yagci, B., Yildirim, C. et al. Orbital color Doppler imaging in Behçet’s disease with or without ocular involvement. Int Ophthalmol 27, 37–42 (2007). https://doi.org/10.1007/s10792-007-9058-5
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DOI: https://doi.org/10.1007/s10792-007-9058-5