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Ocular vasculitis in Behçet's disease

A pathological and immunohistochemical study

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Abstract

The clinical and pathological presentation of Behçet's disease are discussed. Necrotising arteriolitis and phlebitis with thromboses are demonstrated when a rare enucleation specimen became available for examination in this condition. Immunohistochemical studies show mural IgG, IgA, and C3 deposits in episcleral and some choroidal veins. The value of the clinical use of fibrinolytic agents is discussed.

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References

  1. Adamantiadis, B. Sur un cas d'iritis à hypopyon récidivanté. Ann. Oculist 168: 271 (1931).

    Google Scholar 

  2. Behçet, H. Über rezidivierende aphthose durch ein Virus verursachte Geschwüre am Mund, am Auge und an den Genitalien. Derm. Wschr. 105: 1152 (1937).

    Google Scholar 

  3. Bietti, G.B., F. Bruna. International Symposium on Behçet's Disease Rome, pp. 79–110. Karger, Basel/New York (1966).

    Google Scholar 

  4. Braley, A. A case of Behçet's disease. Trans. Amer. Ophthal. Soc. 62: 712–715 (1958).

    Google Scholar 

  5. Collum, L.M.T., J. Mullaney & R. Bowell. Current concepts of Behçet's disease. Trans Ophthal. Soc. U.K. 101: 422–428 (1981).

    Google Scholar 

  6. Fenton, R.H. & H.A. Easom. Behçet's syndrome: A histopathologic study of the eye. Arch. Ophthal. 72: 71–81 (1964).

    Google Scholar 

  7. Fishof, F. Behçet's syndrome. Report of two cases. J. Int. Coll. Surg. 34: 213–229 (1960).

    Google Scholar 

  8. Gilbert, W. Pathologisch-anatomische Befunde bei Iridocyclitis septica. Arch. Augenheilk. 87: 27–34 (1921).

    Google Scholar 

  9. Green, W.R., B.S. Koo. Behçet's disease. Surv. Ophth. 13: 324–332 (1967).

    Google Scholar 

  10. Hippel, E. Ein Fall von Iridocyclitis mit rezidivierendem Hypopyon mit anatomischem Befund. Graefes Arch. Ophthal. 128: 272 (1932).

    Google Scholar 

  11. Ikui, H., Y. Tawara, K. Nakamizo et al. Further studies on histopathology of the eyeballs of Behçet's disease. Jpn. J. Clin. Ophthalmol. 14: 529–540 (1960).

    Google Scholar 

  12. Mamo, J.G., A. Baghdassarian. Behçet's syndrome. Arch. Ophth. 71: 38–48 (1964).

    Google Scholar 

  13. Martin, J.D. Behçet's disease. Arch. Ophthalmol. 52: 272–274 (1954).

    Google Scholar 

  14. Michelson, J.B. & F.V. Chisari. Behçet's disease. Sur. Ophth. 26 (4): 190–203 (1982).

    Google Scholar 

  15. Mishima, S., K. Masuda, Y. Izawa & M. Mochizuki. Behçet's disease in Japan: Ophthalmologic aspects. Tr. Am. Ophth. Soc. LXXVII: 225–279 (1979).

    Google Scholar 

  16. Müller, H. Zur Klinik und Histologie der rezidivierende Hypopyon-Uvetiis mit Angiitis obliterans der Retia. Klin. Monatsbl. Augenheilk. 129: 289–300 (1956).

    Google Scholar 

  17. Schmidt, R. Zum Krankheitsbild der rezidivierenden Hypopyon-Iritis. Graefes Arch. Ophthal. 142: 185–202 (1941).

    Google Scholar 

  18. Sezer, F.N. Further investigations on the virus of Behçet's disease. Amer. J. Ophth. 41: 41–55 (1956).

    Google Scholar 

  19. Shikano, S. Ocular pathology of Behçet's syndrome. International symposium Behçet's Disease Rome, pp. 111–136. Karger, Basel/New York (1966).

    Google Scholar 

  20. Urbanek, J. Fall von rezidivierenden Hypopyon-Iritis. Z. Augenheilk. 91: 320–321 (1937).

    Google Scholar 

  21. Weve, H. Über rezidivierenden allergische Staphylokokkenuveitis. Arch. Augenheilk. 93: 14–39 (1923).

    Google Scholar 

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Authors and Affiliations

  1. Royal Victoria Eye & Ear Hospital, Adelaide Road, 2, Dublin, Ireland

    Joan Mullaney & L. M. T. Collum

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  1. Joan Mullaney
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  2. L. M. T. Collum
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Read at Joint European Ophthalmic Pathology Society/Verhoeff Society Meeting, Geneva, 1981.

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Mullaney, J., Collum, L.M.T. Ocular vasculitis in Behçet's disease. Int Ophthalmol 7, 183–191 (1985). https://doi.org/10.1007/BF00128365

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