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High genetic differentiation between an African and a non-African strain of Drosophila simulans revealed by segregation distortion and reduced crossover frequency

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Abstract

Drosophila simulans strains originating from Madagascar and nearby islands in the Indian Ocean often differ from those elsewhere in the number of sex comb teeth and the degree of morphological anomaly in hybrids with D. melanogaster. Here, we report a strong segregation distortion in the F1 intercross between two D. simulans strains originating from Madagascar and the US, possibly at both the gametic and zygotic levels. Strong bias against alleles of the Madagascar strain was observed for all ten marker loci distributed over the entire second chromosome in the F1 intercross, but only a few showed a weak distortion in the isogenic backgrounds of either strains. Significant deviations of genotype frequencies from Hardy–Weinberg proportions were consistently observed for the second chromosome. By contrast, the X and third chromosomes did not show any strong segregation distortion. Crossover frequency on the second chromosome was uniformly reduced in isogenic backgrounds whereas the map lengths in the F1 intercross were comparable to or larger than that of the standard D. melanogaster map. We discuss these findings in relation to previous studies on other traits and interspecific differences between D. mauritiana, which is endemic to Mauritius Island, and D. simulans.

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Acknowledgments

We express our thanks to Yuriko Ishii for technical assistance. We also thank two anonymous reviewers for helpful comments and for pointing out errors in an earlier version of this paper. This work was supported in part by the Yamada Science Foundation (T.T.-S.), the Mitsubishi Foundation (T.T.-S.) and Grants-in-Aid for Scientific Research (C) (T.T.-S.).

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Author notes

  1. Haruki Tatsuta

    Present address: Laboratory of Subtropical Zoology, Graduate School of Agriculture, University of the Ryukyus, Okinawa, 903-0213, Japan

Authors and Affiliations

  1. Department of Population Genetics, National Institute of Genetics, Mishima, Shizuoka, 411-8540, Japan

    Haruki Tatsuta & Toshiyuki Takano-Shimizu

  2. Department of Genetics, Graduate University for Advanced Studies (SOKENDAI), Mishima, Shizuoka, 411-8540, Japan

    Toshiyuki Takano-Shimizu

  3. Department of Biosystems Science, Graduate University for Advanced Studies (SOKENDAI), Hayama, Kanagawa, 240-0193, Japan

    Toshiyuki Takano-Shimizu

  4. Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, 113-0033, Japan

    Toshiyuki Takano-Shimizu

Authors
  1. Haruki Tatsuta
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  2. Toshiyuki Takano-Shimizu
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Correspondence to Toshiyuki Takano-Shimizu.

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Tatsuta, H., Takano-Shimizu, T. High genetic differentiation between an African and a non-African strain of Drosophila simulans revealed by segregation distortion and reduced crossover frequency. Genetica 137, 165–171 (2009). https://doi.org/10.1007/s10709-009-9381-z

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  • DOI: https://doi.org/10.1007/s10709-009-9381-z

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