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Nutritional and ameliorative effects of dietary curcumin and its nano-silica and nano-zeolite encapsulated forms on growth, biochemical and fatty acid profile of common carp (Cyprinus carpio)

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Abstract

The present study aimed to examine individual nutritional and ameliorative effects of silica nanoparticles (SiO2NPs) and natural zeolite nanoparticles (ZeNPs) and their potential role as carriers to alter the bioavailability of curcumin. Common carps (Cyprinus carpio) were fed during 60 days with a control diet, and curcumin, turmeric, SiO2NPs, curcumin-loaded SiO2NPs, ZeNPs, and curcumin-loaded ZeNPs each at 1, 50, 6.15, 7.15, 39, and 40 g/kg diet, respectively. The highest weight gain (WG) and specific growth rate (SGR) were observed in fish fed with turmeric (P < 0.05). Moreover, dietary curcumin and ZeNPs increased the content of monounsaturated fatty acids (P < 0.05). After exposure to silver nanoparticles (AgNPs), the lowest amount of aspartate aminotransferase (AST) was obtained in fish fed with curcumin (P < 0.05). In addition, alanine aminotransferase (ALT) decreased significantly in the negative control, curcumin, and curcumin-loaded SiO2NPs treatments in comparison to the positive control group (P < 0.05). The lowest silver accumulation was observed in the negative control and SiO2NPs groups (P < 0.05). This experiment demonstrated that while the nanoencapsulation of curcumin on SiO2NPs and ZeNPs did not enhanced the impact of curcumin on the growth and biochemical factors of carps, it can still be considered a potential dietary supplement for enhancing growth and antioxidant indices when added individually to the diet.

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Funding

This study was financially granted by the University of Kurdistan (UOK, Iran) under research grant No. GRC97-06503-1.

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Authors and Affiliations

  1. Department of Fisheries, Faculty of Natural Resources, University of Kurdistan, 66177-15175, P.O. Box 416, Sanandaj, Kurdistan, Iran

    Shadieh Moradi, Fereshteh Pirani, Seyed Ali Johari & Edris Ghaderi

  2. Centre of Marine Sciences (CCMAR), Universidade do Algarve, Campus de Gambelas, 8005-139, Faro, Portugal

    Samyar Ashouri

  3. H&H Bio., Inc. Toxicological Research Center, Hoseo University, Asan, Republic of Korea

    Hoi Pin Kim

  4. HCT America, Seattle, USA

    Il Je Yu

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  1. Shadieh Moradi
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  2. Samyar Ashouri
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  4. Seyed Ali Johari
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  5. Hoi Pin Kim
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Contributions

Sh. M. and F. P.: Investigation, data curation, formal analysis. S. A.: Data curation, writing — original draft. S. A. J.: Conceptualization, supervision, funding acquisition, project administration, validation, writing — review and editing. H. P. K. and E. Gh.: Investigation. I. J. Y.: Project administration

Corresponding author

Correspondence to Seyed Ali Johari.

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All the animals were treated humanely as regards the alleviation of suffering, and all the laboratory procedures involving the animals were reviewed and approved by an Animal Care and Use Committee following the Animal Welfare Act and Interagency Research Animal Committee guidelines (Nickum et al. 2004).

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Highlights

• SiO2NPs and ZeNPs were used as nanocarriers of curcumin in fish diets.

• Growth indices, biochemical factors, and fatty acids were measured after feeding trial.

• Liver enzymes, antioxidant status, and Ag accumulation were analyzed after AgNPs exposure.

• Curcumin was more effective when it was supplemented without nanocarriers.

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Moradi, S., Ashouri, S., Pirani, F. et al. Nutritional and ameliorative effects of dietary curcumin and its nano-silica and nano-zeolite encapsulated forms on growth, biochemical and fatty acid profile of common carp (Cyprinus carpio). Fish Physiol Biochem 49, 599–612 (2023). https://doi.org/10.1007/s10695-023-01209-1

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  • DOI: https://doi.org/10.1007/s10695-023-01209-1

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