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Ecotoxicological risk assessment and seasonal variation of some pharmaceuticals and personal care products in the sewage treatment plant and surface water bodies (lakes)

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Abstract

This paper reports the seasonal variation and environmental quality control data for five fingerprint pharmaceuticals and personal care products (PPCPs) (acetaminophen ciprofloxacin, caffeine, irgasan and benzophenone) in the influent and the effluent of the sewage treatment plant (STP) and surface water bodies (six major lakes) in and around Nagpur, one of the “A class city” in the central India over a period of 1 year. The target compounds were analysed using developed offline solid-phase extraction (SPE) coupled with reversed phase high-performance liquid chromatography (RP-HPLC-PDA) method. All the five PPCPs were found in the influent, whereas four were found in the effluent of the STP. However, in the surface water bodies, three PPCPs were detected in all the seasons. Above PPCPs were present in the concentration range of 1–174 μg L−1 in the surface water bodies, 12–373 μg L−1 in the influent and 11–233 μg L−1 in the effluent of the STP. Amongst the five PPCPs, caffeine was found to be in higher concentration as compared to others. The seasonal trends indicate higher concentrations of PPCPs in summer season and lowest in the rainy season. Additionally, physico-chemical characterisations (inorganic and organic parameters) of the collected samples were performed to access the anthropogenic pollution. Ecotoxicological risk assessment was done to appraise the degree of toxicity of the targeted compounds. Hazard quotient (HQ) values were found to be < 1 indicating no adverse effect on the targeted organism.

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References

  • Agerstrand, M., Berg, C., Bjorlenius, B., Breitholtz, M., Brunstrom, B., Fick, J., et al. (2015). Improving environmental risk assessment of human pharmaceuticals. Environmental Science & Technology, 49(9), 5336–5345.

    Article  Google Scholar 

  • American Public Health Association. (1996). In L. S. Clesceri (Ed.), Standard methods for the examination of water and wastewater, supplement. Washington, DC: American Public Health Association.

    Google Scholar 

  • Aragon, D. M., Ruidiaz, M. A., Vargas, E. F., Bregni, C., Chiappetta, D. A., Sosnik, A., & Martiinez, F. (2008). Solubility of the antimicrobial agent triclosan in organic solvents of different hydrogen bonding capabilities at several temperatures. Journal of Chemical & Engineering Data, 53(11), 2576–2580.

    Article  CAS  Google Scholar 

  • Archana, G., Dhodapkar, R., & Kumar, A. (2016). Offline solid-phase extraction for preconcentration of pharmaceuticals and personal care products in environmental water and their simultaneous determination using the reversed phase high-performance liquid chromatography method. Environmental Monitoring and Assessment, 188(9), 512.

    Article  Google Scholar 

  • Babic, S., Perisa, M., & Skoric, I. (2013). Photolytic degradation of norfloxacin, enrofloxacin and ciprofloxacin in various aqueous media. Chemosphere, 91(11), 1635–1642.

    Article  CAS  Google Scholar 

  • Bedoux, G., Roig, B., Thomas, O., Dupont, V., & Le Bot, B. (2012). Occurrence and toxicity of antimicrobial triclosan and by-products in the environment. Environmental Science and Pollution Research, 19(4), 1044–1065.

    Article  CAS  Google Scholar 

  • Behera, S. K., Kim, H. W., Oh, J. E., & Park, H. S. (2011). Occurrence and removal of antibiotics, hormones and several other pharmaceuticals in wastewater treatment plants of the largest industrial city of Korea. Science of the Total Environment, 409(20), 4351–4360.

    Article  CAS  Google Scholar 

  • Birosova, L., Mackulak, T., Bodik, I., Ryba, J., Skubak, J., & Grabic, R. (2014). Pilot study of seasonal occurrence and distribution of antibiotics and drug resistant bacteria in wastewater treatment plants in Slovakia. Science of the Total Environment, 490, 440–444.

    Article  CAS  Google Scholar 

  • Blair, B. D., Crago, J. P., Hedman, C. J., & Klaper, R. D. (2013). Pharmaceuticals and personal care products found in the Great Lakes above concentrations of environmental concern. Chemosphere, 93(9), 2116–2123.

    Article  CAS  Google Scholar 

  • Bu, Q., Wang, B., Huang, J., Deng, S., & Yu, G. (2013). Pharmaceuticals and personal care products in the aquatic environment in China: a review. Journal of Hazardous Materials, 262, 189–211.

    Article  CAS  Google Scholar 

  • Bueno, M. M., Gomez, M. J., Herrera, S., Hernando, M. D., Aguera, A., & Fernandez-Alba, A. R. (2012). Occurrence and persistence of organic emerging contaminants and priority pollutants in five sewage treatment plants of Spain: two years pilot survey monitoring. Environmental Pollution, 164, 267–273.

    Article  CAS  Google Scholar 

  • Buerge, I. J., Poiger, T., Muller, M. D., & Buser, H. R. (2003). Caffeine, an anthropogenic marker for wastewater contamination of surface waters. Environmental Science & Technology, 37(4), 691–700.

    Article  CAS  Google Scholar 

  • Chiu, C. A., Westerhoff, P., Herckes, P., & Masles, M. (2009). Monitoring of Trace-Level Pharmaceuticals and Personal Care Products in Salt River Project Waters. http://faculty.engineering.asu.edu/pwesterhoff/wp-content/uploads/2012/10/PPCP_EDC-FINAL-report-2010.pdf.

  • Chu, S., & Metcalfe, C. D. (2007). Analysis of paroxetine, fluoxetine and norfluoxetine in fish tissues using pressurized liquid extraction, mixed mode solid phase extraction cleanup and liquid chromatography–tandem mass spectrometry. Journal of Chromatography A, 1163(1), 112–118.

    Article  CAS  Google Scholar 

  • Comeau, F., Surette, C., Brun, G. L., & Losier, R. (2008). The occurrence of acidic drugs and caffeine in sewage effluents and receiving waters from three coastal watersheds in Atlantic Canada. Science of the Total Environment, 396(2), 132–146.

    Article  CAS  Google Scholar 

  • Dalla Bona, M., Zounkova, R., Merlanti, R., Blaha, L., & De Liguoro, M. (2015). Effects of enrofloxacin, ciprofloxacin, and trimethoprim on two generations of Daphnia magna. Ecotoxicology and Environmental Safety, 113, 152–158.

    Article  CAS  Google Scholar 

  • Daneshvar, A., Aboulfadl, K., Viglino, L., Broseus, R., Sauve, S., Madoux-Humery, A. S., & Prevost, M. (2012). Evaluating pharmaceuticals and caffeine as indicators of fecal contamination in drinking water sources of the Greater Montreal region. Chemosphere, 88(1), 131–139.

    Article  CAS  Google Scholar 

  • Daughton, C. G., & Ternes, T. A. (1999). Pharmaceuticals and personal care products in the environment: agents of subtle change? Environmental Health Perspectives, 107, 907.

    Article  CAS  Google Scholar 

  • Desta, M. B. (2013). Batch sorption experiments: Langmuir and Freundlich isotherm studies for the adsorption of textile metal ions onto teff straw (Eragrostis tef ) agricultural waste. Journal of thermodynamics, 1, 1–6.

  • Diwan, V., Lundborg, C. S., & Tamhankar, A. J. (2013). Seasonal and temporal variation in release of antibiotics in hospital wastewater: estimation using continuous and grab sampling. PloS One, 8(7), e68715.

    Article  CAS  Google Scholar 

  • Dorne, J. L. C. M., Skinner, L., Frampton, G. K., Spurgeon, D. J., & Ragas, A. M. J. (2007). Human and environmental risk assessment of pharmaceuticals: differences, similarities, lessons from toxicology. Analytical and Bioanalytical Chemistry, 387(4), 1259–1268.

    Article  CAS  Google Scholar 

  • Dussault, E. B., Balakrishnan, V. K., Sverko, E. D., Solomon, K. R., & Sibley, P. K. (2008). Toxicity of human pharmaceuticals and personal care products to benthic invertebrates. Environmental Toxicology and Chemistry, 27(2), 425–432.

    Article  CAS  Google Scholar 

  • Escher, B. I., Baumgartner, R., Koller, M., Treyer, K., Lienert, J., & McArdell, C. S. (2011). Environmental toxicology and risk assessment of pharmaceuticals from hospital wastewater. Water Research, 45(1), 75–92.

    Article  CAS  Google Scholar 

  • Fent, K., Weston, A. A., & Caminada, D. (2006). Ecotoxicology of human pharmaceuticals. Aquatic Toxicology, 76(2), 122–159.

    Article  CAS  Google Scholar 

  • Fick, J., Soderstrom, H., Lindberg, R. H., Phan, C., Tysklind, M., & Larsson, D. G. (2009). Contamination of surface, ground, and drinking water from pharmaceutical production. Environmental Toxicology and Chemistry, 28(12), 2522–2527.

    Article  CAS  Google Scholar 

  • Gerbersdorf, S. U., Cimatoribus, C., Class, H., Engesser, K. H., Helbich, S., Hollert, H., & Seiler, T. B. (2015). Anthropogenic trace compounds (ATCs) in aquatic habitats—research needs on sources, fate, detection and toxicity to ensure timely elimination strategies and risk management. Environment International, 79, 85–105.

    Article  CAS  Google Scholar 

  • Gibbons, S. E., Wang, C., & Ma, Y. (2011). Determination of pharmaceutical and personal care products in wastewater by capillary electrophoresis with UV detection. Talanta, 84(4), 1163–1168.

    Article  CAS  Google Scholar 

  • Girardi, C., Greve, J., Lamshöft, M., Fetzer, I., Miltner, A., Schaffer, A., & Kastner, M. (2011). Biodegradation of ciprofloxacin in water and soil and its effects on the microbial communities. Journal of Hazardous Materials, 198, 22–30.

    Article  CAS  Google Scholar 

  • Gros, M., Petrovic, M., Ginebreda, A., & Barcelo, D. (2010). Removal of pharmaceuticals during wastewater treatment and environmental risk assessment using hazard indexes. Environment International, 36(1), 15–26.

    Article  CAS  Google Scholar 

  • Guerra, P., Kim, M., Shah, A., Alaee, M., & Smyth, S. A. (2014). Occurrence and fate of antibiotic, analgesic/anti-inflammatory, and antifungal compounds in five wastewater treatment processes. Science of the Total Environment, 473, 235–243.

    Article  Google Scholar 

  • Guo, H. G., Gao, N. Y., Chu, W. H., Li, L., Zhang, Y. J., Gu, J. S., & Gu, Y. L. (2013). Photochemical degradation of ciprofloxacin in UV and UV/H2O2 process: kinetics, parameters, and products. Environmental Science and Pollution Research, 20(5), 3202–3213.

    Article  CAS  Google Scholar 

  • Hagenbuch, I. M., & Pinckney, J. L. (2012). Toxic effect of the combined antibiotics ciprofloxacin, lincomycin, and tylosin on two species of marine diatoms. Water Research, 46(16), 5028–5036.

    Article  CAS  Google Scholar 

  • Han, G. H., Hur, H. G., & Kim, S. D. (2006). Ecotoxicological risk of pharmaceuticals from wastewater treatment plants in Korea: occurrence and toxicity to Daphnia magna. Environmental Toxicology and Chemistry, 25(1), 265–271.

    Article  CAS  Google Scholar 

  • Han, J., Won, E. J., Hwang, U. K., Kim, I. C., Yim, J. H., & Lee, J. S. (2016). Triclosan (TCS) and triclocarban (TCC) cause lifespan reduction and reproductive impairment through oxidative stress-mediated expression of the defensome in the monogonont rotifer (Brachionus koreanus). Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, 185, 131–137.

    Google Scholar 

  • Heberer, T. (2002). Occurrence, fate, and removal of pharmaceutical residues in the aquatic environment: a review of recent research data. Toxicology Letters, 131(1), 5–17.

    Article  CAS  Google Scholar 

  • Hedgespeth, M. L., Sapozhnikova, Y., Pennington, P., Clum, A., Fairey, A., & Wirth, E. (2012). Pharmaceuticals and personal care products (PPCPs) in treated wastewater discharges into Charleston Harbor, South Carolina. Science of the Total Environment, 437, 1–9.

    Article  CAS  Google Scholar 

  • Hoque, M. E., Cloutier, F., Arcieri, C., McInnes, M., Sultana, T., Murray, C., & Metcalfe, C. D. (2014). Removal of selected pharmaceuticals, personal care products and artificial sweetener in an aerated sewage lagoon. Science of the Total Environment, 487, 801–812.

    Article  CAS  Google Scholar 

  • Jasim, S. Y., Irabelli, A., Yang, P., Ahmed, S., & Schweitzer, L. (2006). Presence of pharmaceuticals and pesticides in Detroit River water and the effect of ozone on removal. Ozone: Science and Engineering, 28(6), 415–423.

    Article  CAS  Google Scholar 

  • Jeon, H. K., Chung, Y., & Ryu, J. C. (2006). Simultaneous determination of benzophenone-type UV filters in water and soil by gas chromatography–mass spectrometry. Journal of Chromatography A, 1131(1), 192–202.

    Article  CAS  Google Scholar 

  • Jeong, S. H., Song, Y. K., & Cho, J. H. (2009). Risk assessment of ciprofloxacin, flavomycin, olaquindox and colistinsulfate based on microbiological impact on human gut biota. Regulatory Toxicology and Pharmacology, 53(3), 209–216.

    Article  CAS  Google Scholar 

  • Jjemba, P. K. (2006). Excretion and ecotoxicity of pharmaceutical and personal care products in the environment. Ecotoxicology and Environmental Safety, 63(1), 113–130.

    Article  CAS  Google Scholar 

  • Johansson, C. H., Janmar, L., & Backhaus, T. (2014). Toxicity of ciprofloxacin and sulfamethoxazole to marine periphytic algae and bacteria. Aquatic Toxicology, 156, 248–258.

    Article  CAS  Google Scholar 

  • Jones, O. A. H., Voulvoulis, N., & Lester, J. N. (2002). Aquatic environmental assessment of the top 25 English prescription pharmaceuticals. Water Research, 36(20), 5013–5022.

    Article  CAS  Google Scholar 

  • Kameda, Y., Kimura, K., & Miyazaki, M. (2011). Occurrence and profiles of organic sun-blocking agents in surface waters and sediments in Japanese rivers and lakes. Environmental Pollution, 159(6), 1570–1576.

    Article  CAS  Google Scholar 

  • Kasprzyk-Hordern, B., Dinsdale, R. M., & Guwy, A. J. (2009). The removal of pharmaceuticals, personal care products, endocrine disruptors and illicit drugs during wastewater treatment and its impact on the quality of receiving waters. Water Research, 43(2), 363–380.

    Article  CAS  Google Scholar 

  • Kienhuis, A. S., Bessems, J. G., Pennings, J. L., Driessen, M., Luijten, M., et al. (2011). Application of toxicogenomics in hepatic systems toxicology for risk assessment: acetaminophen as a case study. Toxicology and Applied Pharmacology, 250(2), 96–107.

    Article  CAS  Google Scholar 

  • Kim, S., & Choi, K. (2014). Occurrences, toxicities, and ecological risks of benzophenone-3, a common component of organic sunscreen products: a mini-review. Environment International, 70, 143–157.

    Article  CAS  Google Scholar 

  • Kim, J. W., Yoon, S. M., Lee, S. J., Narumiya, M., Nakada, N., Han, I. S., et al. (2012). Occurrence and fate of PPCPs wastewater treatment plants in Korea. In 2nd International Conference on Environment and Industrial Innovation, Singapore vol. 35, pp. 57–61.

  • Kolpin, D. W., Furlong, E. T., Meyer, M. T., Thurman, E. M., Zaugg, S. D., Barber, L. B., & Buxton, H. T. (2002). Pharmaceuticals, hormones, and other organic wastewater contaminants in US streams, 1999-2000: a national reconnaissance. Environmental Science & Technology, 36(6), 1202–1211.

    Article  CAS  Google Scholar 

  • Kosma, C. I., Lambropoulou, D. A., & Albanis, T. A. (2010). Occurrence and removal of PPCPs in municipal and hospital wastewaters in Greece. Journal of Hazardous Materials, 179(1), 804–817.

    Article  CAS  Google Scholar 

  • Leung, H. W., Jin, L., Wei, S., Tsui, M. M. P., Zhou, B., et al. (2013). Pharmaceuticals in tap water: human health risk assessment and proposed monitoring framework in China. Environmental Health Perspectives, 121(7), 839.

    Article  Google Scholar 

  • Li, W., Ma, Y., Guo, C., Hu, W., Liu, K., Wang, Y., & Zhu, T. (2007). Occurrence and behavior of four of the most used sunscreen UV filters in a wastewater reclamation plant. Water Research, 41(15), 3506–3512.

    Article  CAS  Google Scholar 

  • Lin, T., Yu, S., & Chen, W. (2016). Occurrence, removal and risk assessment of pharmaceutical and personal care products (PPCPs) in an advanced drinking water treatment plant (ADWTP) around Taihu Lake in China. Chemosphere, 152, 1–9.

    Article  CAS  Google Scholar 

  • Liu, B. Y., Nie, X. P., Liu, W. Q., Snoeijs, P., Guan, C., & Tsui, M. T. (2011). Toxic effects of erythromycin, ciprofloxacin and sulfamethoxazole on photosynthetic apparatus in Selenastrum capricornutum. Ecotoxicology and Environmental Safety, 74(4), 1027–1035.

    Article  CAS  Google Scholar 

  • Luo, Y., Guo, W., Ngo, H. H., et al. (2014). A review on the occurrence of micropollutants in the aquatic environment and their fate and removal during wastewater treatment. Science of the Total Environment, 473-474, 619–641.

    Article  CAS  Google Scholar 

  • Marques, R. R., Sampaio, M. J., Carrapico, P. M., Silva, C. G., Morales-Torres, S., et al. (2013). Photocatalytic degradation of caffeine: developing solutions for emerging pollutants. Catalysis Today, 209, 108–115.

    Article  CAS  Google Scholar 

  • Miege, C., Choubert, J. M., Ribeiro, L., Eusebe, M., & Coquery, M. (2009). Fate of pharmaceuticals and personal care products in wastewater treatment plants–conception of a database and first results. Environmental Pollution, 157(5), 1721–1726.

    Article  CAS  Google Scholar 

  • Moore, M. T., Greenway, S. L., Farris, J. L., & Guerra, B. (2008). Assessing caffeine as an emerging environmental concern using conventional approaches. Archives of Environmental Contamination and Toxicology, 54(1), 31–35.

    Article  CAS  Google Scholar 

  • Mottaleb, M. A., Bellamy, M. K., Mottaleb, M. A., & Islam, M. R. (2015). Use of LC-MS and GC-MS methods to measure emerging contaminants pharmaceutical and personal care products (PPCPs) in fish. Journal of Chromatography & Separation Techniques, 6(3), 1.

    Article  Google Scholar 

  • Mutiyar, P. K., & Mittal, A. K. (2014). Risk assessment of antibiotic residues in different water matrices in India: key issues and challenges. Environmental Science and Pollution Research, 21(12), 7723–7736.

    Article  CAS  Google Scholar 

  • Naslund, J., Hedman, J. E., & Agestrand, C. (2008). Effects of the antibiotic ciprofloxacin on the bacterial community structure and degradation of pyrene in marine sediment. Aquatic Toxicology, 90(3), 223–227.

    Article  Google Scholar 

  • Nunes, B., Antunes, S. C., Santos, J., Martins, L., & Castro, B. B. (2014). Toxic potential of paracetamol to freshwater organisms: a headache to environmental regulators? Ecotoxicology and Environmental Safety, 107, 178–185.

    Article  CAS  Google Scholar 

  • Oulton, R. L., Kohn, T., & Cwiertny, D. M. (2010). Pharmaceuticals and personal care products in effluent matrices: a survey of transformation and removal during wastewater treatment and implications for wastewater management. Journal of Environmental Monitoring, 12(11), 1956–1978.

    Article  CAS  Google Scholar 

  • Prescott, L. F. (1980). Kinetics and metabolism of paracetamol and phenacetin. British Journal of Clinical Pharmacology, 10(S2), 291S–298S.

    Article  Google Scholar 

  • Puri, P. J., Yenkie, M. K. N., Sangal, S. P., Gandhare, N. V., Sarote, G. B., & Dhanorkar, D. B. (2011). Surface water (lakes) quality assessment in Nagpur city (India) based on water quality index (WQI). Rasayan Journal of Chemistry, 4(1), 43–48.

    CAS  Google Scholar 

  • Puri, P. J., Yenkie, M. K. N., Rana, D. B., Meshram, S. U., & Awale, L. S. (2015). Surface water (Futala Lake) quality and its pollution load in terms of water quality index (WQI). Advances in Applied Science Research, 6(1), 15–26.

    CAS  Google Scholar 

  • Radjenovic, J., Petrovic, M., & Barcelo, D. (2007). Analysis of pharmaceuticals in wastewater and removal using a membrane bioreactor. Analytical and Bioanalytical Chemistry, 387(4), 1365–1377.

    Article  CAS  Google Scholar 

  • Reiss, R., Mackay, N., Habig, C., & Griffin, J. (2002). An ecological risk assessment for triclosan in lotic systems following discharge from wastewater treatment plants in the United States. Environmental Toxicology and Chemistry, 21(11), 2483–2492.

    Article  CAS  Google Scholar 

  • Rios, J. M., Lana, N. B., Berton, P., Ciocco, N. F., & Altamirano, J. C. (2015). Use of wild trout for PBDE assessment in freshwater environments: review and summary of critical factors. Emerging Contaminants, 1(1), 54–63.

    Article  Google Scholar 

  • Roberts, J., Kumar, A., Du, J., Hepplewhite, C., Ellis, D. J., Christy, A. G., & Beavis, S. G. (2016). Pharmaceuticals and personal care products (PPCPs) in Australia’s largest inland sewage treatment plant, and its contribution to a major Australian river during high and low flow. Science of the Total Environment, 541, 1625–1637.

    Article  CAS  Google Scholar 

  • Rosal, R., Rodriguez, A., Perdigon-Melon, J. A., Petre, A., Garcia-Calvo, E., Gomez, M. J., & Fernandez-Alba, A. R. (2010). Occurrence of emerging pollutants in urban wastewater and their removal through biological treatment followed by ozonation. Water Research, 44(2), 578–588.

    Article  CAS  Google Scholar 

  • Sipma, J., Osuna, B., Collado, N., Monclús, H., Ferrero, G., Comas, J., & Rodriguez-Roda, I. (2010). Comparison of removal of pharmaceuticals in MBR and activated sludge systems. Desalination, 250(2), 653–659.

    Article  CAS  Google Scholar 

  • Sires, I., Oturan, N., Oturan, M. A., Rodriguez, R. M., Garrido, J. A., & Brillas, E. (2007). Electro-Fenton degradation of antimicrobials triclosan and triclocarban. Electrochimica Acta, 52(17), 5493–5503.

    Article  CAS  Google Scholar 

  • Spongberg, A. L., & Witter, J. D. (2008). Pharmaceutical compounds in the wastewater process stream in Northwest Ohio. Science of the Total Environment, 397(1), 148–157.

    Article  CAS  Google Scholar 

  • Strickland Jr, C. H., Rush, P., & Commissioner, P. D. (2011). 2010 Occurrence of Pharmaceutical and Personal Care Products (PPCPs) in Source Water of the New York City Water Supply. http://www.nyc.gov/html/dep/pdf/quality/nyc_dep_2010_ppcpreport.pdf.

  • Stuer-Lauridsen, F., Birkved, M., Hansen, L. P., Lutzhoft, H. C. H., & Halling-Sorensen, B. (2000). Environmental risk assessment of human pharmaceuticals in Denmark after normal therapeutic use. Chemosphere, 40(7), 783–793.

    Article  CAS  Google Scholar 

  • Subedi, B., & Kannan, K. (2015). Occurrence and fate of select psychoactive pharmaceuticals and antihypertensives in two wastewater treatment plants in New York State, USA. Science of the Total Environment, 514, 273–280.

    Article  CAS  Google Scholar 

  • Sui, Q., Huang, J., Deng, S., Yu, G., & Fan, Q. (2010). Occurrence and removal of pharmaceuticals, caffeine and DEET in wastewater treatment plants of Beijing, China. Water Research, 44(2), 417–426.

    Article  CAS  Google Scholar 

  • Sui, Q., Huang, J., Lu, S., et al. (2014). Removal of pharmaceutical and personal care products by sequential ultraviolet and ozonation process in a full-scale wastewater treatment plant. Frontiers of Environmental Science & Engineering, 8(1), 62–68.

    Article  CAS  Google Scholar 

  • Sun, Q., Lv, M., Hu, A., Yang, X., & Yu, C. P. (2014). Seasonal variation in the occurrence and removal of pharmaceuticals and personal care products in a wastewater treatment plant in Xiamen, China. Journal of Hazardous Materials, 277, 69–75.

    Article  CAS  Google Scholar 

  • Sun, Q., Li, M., Ma, C., Chen, X., Xie, X., & Yu, C. P. (2016). Seasonal and spatial variations of PPCP occurrence, removal and mass loading in three wastewater treatment plants located in different urbanization areas in Xiamen, China. Environmental Pollution, 208, 371–381.

    Article  CAS  Google Scholar 

  • Thomas, P. M., & Foster, G. D. (2005). Tracking acidic pharmaceuticals, caffeine, and triclosan through the wastewater treatment process. Environmental Toxicology and Chemistry, 24(1), 25–30.

    Article  CAS  Google Scholar 

  • Ura, K., Kai, T., Sakata, S., Iguchi, T., & Arizono, K. (2002). Aquatic acute toxicity testing using the nematode Caenorhabditis elegans. Journal of Health Science, 48(6), 583–586.

    Article  CAS  Google Scholar 

  • Van Leeuwen, C. J., Bro-Rasmussen, F., Feijtel, T. C., Arndt, R., Bussian, B. M., Calamari, D., et al. (1996). Risk assessment and management of new and existing chemicals. Environmental Toxicology and Pharmacology, 2(4), 243–299.

    Article  Google Scholar 

  • Vidal-Dorsch, D. E., Bay, S. M., Maruya, K., Snyder, S. A., Trenholm, R. A., & Vanderford, B. J. (2012). Contaminants of emerging concern in municipal wastewater effluents and marine receiving water. Environmental Toxicology and Chemistry, 31(12), 2674–2682.

    Article  CAS  Google Scholar 

  • Vorosmarty, C. J., McIntyre, P. B., Gessner, M. O., Dudgeon, D., Prusevich, A., Green, P., Glidden, S., Bunn, S. E., Sullivan, C. A., Liermann, C. R., & Davies, P. M. (2010). Global threats to human water security and river biodiversity. Nature, 467(7315), 555–561.

    Article  CAS  Google Scholar 

  • Wu, C., Spongberg, A. L., Witter, J. D., Fang, M., & Czajkowski, K. P. (2010). Uptake of pharmaceutical and personal care products by soybean plants from soils applied with biosolids and irrigated with contaminated water. Environmental Science & Technology, 44(16), 6157–6161.

    Article  CAS  Google Scholar 

  • Wu, S., Zhang, L., & Chen, J. (2012). Paracetamol in the environment and its degradation by microorganisms. Applied Microbiology and Biotechnology, 96(4), 875–884.

    Article  CAS  Google Scholar 

  • Xu, J., Wu, L., & Chang, A. C. (2009). Degradation and adsorption of selected pharmaceuticals and personal care products (PPCPs) in agricultural soils. Chemosphere, 77(10), 1299–1305.

    Article  CAS  Google Scholar 

  • Yang, X., Flowers, R. C., Weinberg, H. S., & Singer, P. C. (2011). Occurrence and removal of pharmaceuticals and personal care products (PPCPs) in an advanced wastewater reclamation plant. Water Research, 45(16), 5218–5228.

    Article  CAS  Google Scholar 

  • Zhang, Z., Ren, N., Li, Y. F., Kunisue, T., Gao, D., & Kannan, K. (2011). Determination of benzotriazole and benzophenone UV filters in sediment and sewage sludge. Environmental Science & Technology, 45(9), 3909–3916.

    Article  CAS  Google Scholar 

  • Zhao, J. L., Ying, G. G., Liu, Y. S., Chen, F., Yang, J. F., & Wang, L. (2010). Occurrence and risks of triclosan and triclocarban in the Pearl River system, South China: from source to the receiving environment. Journal of Hazardous Materials, 179(1), 215–222.

    Article  CAS  Google Scholar 

  • Zuccato, E., Castiglioni, S., Bagnati, R., Melis, M., & Fanelli, R. (2010). Source, occurrence and fate of antibiotics in the Italian aquatic environment. Journal of Hazardous Materials, 179(1), 1042–1048.

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Chemistry, Visvesvaraya National Institute of Technology, Nagpur, 440010, India

    G. Archana & Anupama Kumar

  2. Wastewater Technology Division, National Environmental Engineering Research Institute, [CSIR], Nagpur, 440020, India

    Rita Dhodapkar

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  2. Rita Dhodapkar
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  3. Anupama Kumar
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Correspondence to Rita Dhodapkar or Anupama Kumar.

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Archana, G., Dhodapkar, R. & Kumar, A. Ecotoxicological risk assessment and seasonal variation of some pharmaceuticals and personal care products in the sewage treatment plant and surface water bodies (lakes). Environ Monit Assess 189, 446 (2017). https://doi.org/10.1007/s10661-017-6148-3

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  • DOI: https://doi.org/10.1007/s10661-017-6148-3

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