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Simultaneous determination of selected hormones, endocrine disruptor compounds, and pesticides in water medium at trace levels by GC-MS after dispersive liquid-liquid microextraction

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Abstract

The need to enhance food safety has led to major advancements in pesticide productions, and though many benefits have been gained, environmental contamination has also risen from these chemicals that tend to persist in the environment. Some pesticides, together with other chemicals commonly called endocrine disruptor compounds, block the receptor sites of hormones or mimic displaced hormones, leading to imbalanced hormonal levels that result in health disorders and diseases. These chemicals occur at trace levels and are not directly detected by conventional analytical methods. A dispersive liquid-liquid microextraction method was therefore developed for preconcentration of 12 analytes including hormones, endocrine disruptor compounds, and pesticides, to be analyzed by gas chromatography mass spectrometry. This was achieved by optimizing parameters such as extractor solvent type and amount, dispersive solvent type and amount, pH, and salt effect that affect extraction output. The limits of detection and quantification of the developed method were between 0.09 and 3.36 and 0.31 and 11.19 ng mL−1, respectively. The calibration plots of the analytes also showed good linearity and low percent relative standard deviations. Recovery studies were performed for tap water and wastewater samples, and the percent recoveries recorded were between 84 and 109%.

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Acknowledgements

The authors duly acknowledge Yıldız Technical University for the financial support (Scientific Research Project, 2016-01-02-KAP04).

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Authors and Affiliations

  1. Department of Chemistry, Yıldız Technical University, 34349, İstanbul, Turkey

    Dotse Selali Chormey, Çağdaş Büyükpınar, Fatma Turak & Sezgin Bakırdere

  2. Department of Environmental Engineering, Ataturk University, 25250, Erzurum, Turkey

    Okan Tarık Komesli

Authors
  1. Dotse Selali Chormey
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  2. Çağdaş Büyükpınar
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  3. Fatma Turak
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  4. Okan Tarık Komesli
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  5. Sezgin Bakırdere
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Corresponding author

Correspondence to Sezgin Bakırdere.

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Highlights

• A dispersive liquid-liquid microextraction method was developed for the preconcentration of 12 analytes

• All of the system parameters were optimized.

• The limits of detection and quantification of the developed method were between 0.09 and 5.69 and 0.31 and 18.96 ng mL−1, respectively

• The spiking experiment at different concentrations revealed satisfactory recoveries for tap water and wastewater.

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Chormey, D.S., Büyükpınar, Ç., Turak, F. et al. Simultaneous determination of selected hormones, endocrine disruptor compounds, and pesticides in water medium at trace levels by GC-MS after dispersive liquid-liquid microextraction. Environ Monit Assess 189, 277 (2017). https://doi.org/10.1007/s10661-017-6003-6

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  • DOI: https://doi.org/10.1007/s10661-017-6003-6

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