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Inverse correlation among organochlorine pesticide levels to total lipid serum contents: a preliminary study in Veracruz, México

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Abstract

Organochlorine pesticides, due to their hydrophobic nature and persistence, accumulate in tissues rich in lipids, which had been used as a biomarker for environmental pollution. In humans, organochlorine pesticides are continuously circulating and equilibrating among body compartments. The objective of the study was to evaluate the concentrations of organochlorine pesticides in blood serum and compare their levels to the total lipid contents in Veracruz, México inhabitants. Our hypothesis is that concentrations of organochlorine pesticides will increase just as lipid concentrations. Levels of organochlorine pesticides were divided in ascending tertils according to their total lipid content. The linear trend model applied surprisingly reveals that the average level of all organochlorine pesticides decreases as the lipid concentration increases. From one tertil to the next β-HCH, it shows a decrease of −3.19 mg kg−1 on lipid basis, pp.′DDE levels decrease by −3.70 mg kg−1 on lipid basis and pp.′DDT levels decrease −1.13 mg kg−1 on lipid basis. We conclude that the levels and the orderly sequence of organochlorine pesticide distributions in the blood serum maintain an inverse relationship to total lipid blood serum concentrations.

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Authors and Affiliations

  1. Centro de Investigaciones Biomédicas, Universidad Veracruzana, Xalapa, Ver, México

    Mario Caba, Enrique Meza & Stefan M. Waliszewski

  2. Universidad de Occidente, Los Mochis, Sin, México

    Carmen Martínez-Valenzuela

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  1. Mario Caba
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  2. Enrique Meza
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  3. Stefan M. Waliszewski
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  4. Carmen Martínez-Valenzuela
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Correspondence to Mario Caba.

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Caba, M., Meza, E., Waliszewski, S.M. et al. Inverse correlation among organochlorine pesticide levels to total lipid serum contents: a preliminary study in Veracruz, México. Environ Monit Assess 187, 467 (2015). https://doi.org/10.1007/s10661-015-4694-0

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