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Organochlorine Pesticide Gradient Levels Among Maternal Adipose Tissue, Maternal Blood Serum and Umbilical Blood Serum

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Abstract

The objective of the present study was to determine levels and calculate ratios of copartition coefficients among organochlorine pesticides β-HCH, pp′DDE, op′DDT and pp′DDT in maternal adipose tissue, maternal blood serum and umbilical blood serum of mother-infant pairs from Veracruz, Mexico. Organochlorine pesticides were analyzed in 70 binomials: maternal adipose tissue, maternal serum and umbilical cord serum samples, using gas chromatography with electron capture detection (GC-ECD). The results were expressed as mg/kg on fat basis. p,p′-DDE was the major organochlorine component, detected in every maternal adipose tissue (0.770 mg/kg), maternal serum sample (5.8 mg/kg on fat basis) and umbilical cord blood sample (6.9 mg/kg on fat basis). p,p′-DDT was detected at 0.101 mg/kg, 2.2 mg/kg and 5.9 mg/kg respectively, according to the order given above. β-HCH was detected at 0.027 mg/kg, 4.2 mg/kg and 28.0 mg/kg respectively. op′DDT was detected only in maternal adipose tissue at 0.011 mg/kg. The copartition coefficients among samples identify significant increases in concentrations from adipose tissue to maternal blood serum and to umbilical blood serum. The increase indicated that maternal adipose tissue released organochlorine pesticides to blood serum and that they are carried over to umbilical cord blood.

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Acknowledgments

The authors express their appreciation to Winston Smith of the Peace Corps México for his help in editing this article.

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Authors and Affiliations

  1. Biomedical Sciences Doctor Study, University of Veracruz, Xalapa, Mexico

    Margarita Herrero-Mercado

  2. Institute of Forensic Medicine, University of Veracruz, SS Juan Pablo II s/n, 91890, Boca del Rio, Mexico

    S. M. Waliszewski

  3. Biomedical Research Center, University of Veracruz, Xalapa, Mexico

    M. Caba

  4. Department of Biological Sciences, West University, Los Mochis Sin., Mexico

    C. Martínez-Valenzuela

  5. Center of Atmospheric Sciences, UNAM, Mexico City, Mexico

    S. Gómez Arroyo & R. Villalobos Pietrini

  6. University Autonomous of Nuevo León, Monterrey, Mexico

    P. C. Cantú Martínez

  7. IMSS Hospital Veracruz, Veracruz, Mexico

    F. Hernández-Chalate

Authors
  1. Margarita Herrero-Mercado
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  2. S. M. Waliszewski
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  3. M. Caba
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  4. C. Martínez-Valenzuela
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  5. S. Gómez Arroyo
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  6. R. Villalobos Pietrini
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  7. P. C. Cantú Martínez
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  8. F. Hernández-Chalate
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Corresponding author

Correspondence to S. M. Waliszewski.

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Herrero-Mercado, M., Waliszewski, S.M., Caba, M. et al. Organochlorine Pesticide Gradient Levels Among Maternal Adipose Tissue, Maternal Blood Serum and Umbilical Blood Serum. Bull Environ Contam Toxicol 86, 289–293 (2011). https://doi.org/10.1007/s00128-011-0204-4

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  • DOI: https://doi.org/10.1007/s00128-011-0204-4

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