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Field application of SPME as a novel tool for occupational exposure assessment with inhalational anesthetics

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Abstract

Occupational exposure to inhalational anesthetics occurs routinely in operating rooms. It could induce serious health hazards and diseases. This exposure assessment is a crucial step in determining risks. In this study, a pen-shaped holder for solid-phase microextraction (SPME) sampler was successfully applied as a time-weighted average sampling tool for workshift exposure assessment of operation room staff to halothane. It proved to be very convenient for use in occupational environments such as operation rooms. Samples were analyzed by a gas chromatography–mass spectrometry. The validity of the SPME method was checked in real-world conditions with Occupational Safety and Health Administration (OSHA) 103 standard method for the determination of inhalational anesthetics. A good agreement between OSHA 103 and SPME methods was obtained and results demonstrated no statistically significant differences in anesthetic concentrations determined by the two analytical methods (p ≥ 0.05). It is concluded that SPME in retracted mode could successfully be applied in occupational exposure assessment purposes.

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Acknowledgments

The authors thank the Hamadan University of Medical Science for supporting this research. The authors also extend their appreciation to Mr. Mohammad Taghi Zare Sakhvidi for his kind cooperation with the research team for sampling in operating rooms.

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Authors and Affiliations

  1. Department of Occupational Health, Research Centre for Health Sciences, School of Public Health, Hamedan University of Medical Science, Hamadan, Iran

    Mohammad Javad Zare Sakhvidi & AbdulRahman Bahrami

  2. Department of Chemistry, Faculty of Science, Lorestan University, Khoramabad, Iran

    Alireza Ghiasvand

  3. Department of Biostatics and Epidemiology, Research Centre for Health Sciences, School of Public Health, Hamedan University of Medical Science, Hamedan, Iran

    Hossein Mahjub

  4. LPTC-Institut des Sciences Moléculaires, UMR 5255 CNRS-Université Bordeaux 1, Site universitaire, 24019, Périgueux Cedex, France

    Ludovic Tuduri

  5. Department of Occupational Health, Research Centre for Health Sciences, School of Public Health, Hamedan University of Medical Science, PO Box 4171-65175, Hamedan, Iran

    AbdulRahman Bahrami

Authors
  1. Mohammad Javad Zare Sakhvidi
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  2. AbdulRahman Bahrami
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  3. Alireza Ghiasvand
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  4. Hossein Mahjub
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  5. Ludovic Tuduri
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Correspondence to AbdulRahman Bahrami.

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Zare Sakhvidi, M.J., Bahrami, A., Ghiasvand, A. et al. Field application of SPME as a novel tool for occupational exposure assessment with inhalational anesthetics. Environ Monit Assess 184, 6483–6490 (2012). https://doi.org/10.1007/s10661-011-2434-7

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  • DOI: https://doi.org/10.1007/s10661-011-2434-7

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