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Short-term effect of ambient ozone pollution on respiratory diseases in western China

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Abstract

Ambient air pollution has been regarded as an important cause of the morbidity and mortality of respiratory diseases. In the current work, a total of 469,490 respiratory emergency room (ER) visits in Lanzhou, China from Jan 1, 2013 to Dec 31, 2016 were collected. A generalized additive model (GAM) was used to investigate the association between O3 and respiratory ER visits for the different gender and age subgroups. The results showed that: (a) with per inter-quartile range (IQR) (31 µg/m3) increase in O3, the greatest relative risk (RR) of respiratory ER visits for the total was 1.014 (95% CI 1.008–1.020) at lag 4 days. Females and 16-to-45-year-olds were relatively more sensitive to O3; (b) the significant lag effects were found in single-day lag models, with the highest RR values for different groups were observed at lag 3-lag 5 days. The multi-day cumulative lag effects were stronger for the total; (c) in the multiple-pollutant models, the effects of O3 were generally increased when introducing other pollutants (PM10, PM2.5, SO2 and NO2) for adjustment. This study demonstrated that short-term exposure to O3 increased the RR of respiratory ER visits in Lanzhou, China.

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References

  • An, X. Q., Ma, A. Q., & Wang, H. L. (2006). Analyzing on air pollution spatial distribution of Lanzhou using GIS. Arid Land Geography, 29(4), 576–581.

    Google Scholar 

  • Barnett, A. G., Williams, G. M., Schwartz, J., et al. (2005). Air pollution and child respiratory health: A case-crossover study in Australia and New Zealand. American Journal of Respiratory Critical Care Medicine, 171, 1272–1278.

    Article  Google Scholar 

  • Bell, M. L., Zanobetti, A., & Dominici, F. (2014). Who is more affected by ozone pollution? A systematic review and Meta-analysis. American Journal of Epidemiology, 180(1), 15–28.

    Article  Google Scholar 

  • Cesaroni, G., Badaloni, C., Porta, D., Forastiere, F., & Perucci, C. A. (2008). Comparison between various indices of exposure to traffic-related air pollution and their impact on respiratory health in adults. Occupied Environmental Medicine, 65, 683–690.

    Article  CAS  Google Scholar 

  • Chan, C. C., Chuang, K. J., Chien, L. C., et al. (2006). Urban air pollution and emergency admissions for cerebrovascular diseases in Taipei. Taiwan. European Heart Journal, 27(10), 1238–1244.

    Article  CAS  Google Scholar 

  • Chatkin, J., Correa, L., & Santos, U. (2021). External environmental pollution as a risk factor for asthma. Clinical Reviews in Allergy and Immunology, 2021, 1–18.

    Google Scholar 

  • Cohen, A. J., Brauer, M., Burnett, R., et al. (2017). Estimates and 25-year trends of the global burden of disease attributable to ambient air pollution: An analysis of data from the Global Burden of Diseases Study 2015. Lancet, 389, 1907–1918.

    Article  Google Scholar 

  • Corradi, M., Alinovi, R., Goldoni, M., et al. (2002). Biomarkers of oxidative stress after controlled human exposure to ozone. Toxicology Letters, 134(1–3), 219–225.

    Article  CAS  Google Scholar 

  • de Freitas, C. U., de Leon, A. P., Juger, W., & Gouveia, N. (2016). Air pollution and its impacts on health in Vitoria, Espirito Santo, Brazil. Rev Saúde Pública, 50, 4.

    Article  Google Scholar 

  • Díaz, J., Ortiz, C., Falcón, I., et al. (2018). Short-term effect of tropospheric ozone on daily mortality in Spain. Atmospheric Environment, 187, 107–116.

    Article  Google Scholar 

  • GBD 2019 Risk Factors Collaborators. (2019). The Lancet: Latest global disease estimates reveal perfect storm of rising chronic diseases and public health failures fuelling COVID-19 pandemic. Lancet

  • Harms, C. A. (2006). Does gender affect pulmonary function and exercise capacity? Respiratory Physiology and Neurobiology, 151(2–3), 124–131.

    Article  Google Scholar 

  • Ji, M., Cohan, D. S., & Bell, M. L. (2011). Meta-analysis of the association between short-term exposure to ambient ozone and respiratory hospital admissions. Environmental Research Letters, 6(2), 24006–24016.

    Article  Google Scholar 

  • Kariisa, M., Foraker, R., Pennell, M., et al. (2015). Short- and long-term effects of ambient ozone and fine particulate matter on the respiratory health of chronic obstructive pulmonary disease subjects. Archives of Environmental and Occupational Health, 70(1), 56–62.

    Article  CAS  Google Scholar 

  • Künzli, N., Jerrett, M., Mack, W. J., et al. (2005). Ambient air pollution and atherosclerosis in Los Angeles. Environmental Health Perspectives, 113, 201–206.

    Article  Google Scholar 

  • Li, M. M., Dong, H., Wang, B. G., et al. (2021). Association between ambient ozone pollution and mortality from a spectrum of causes in Guangzhou. China. Science of the Total Environment, 754, 142110.

    Article  CAS  Google Scholar 

  • Luginaah, I. N., Fung, K. Y., Gorey, K. M., et al. (2005). Association of ambient air pollution with respiratory hospitalization in a government-designated “area of concern”: The case of Windsor. Ontario. Environmental Health Perspectives, 113, 290–296.

    Article  Google Scholar 

  • Luo, L. S., Zhang, Y. Q., Jiang, J. F., et al. (2018). Short-term effects of ambient air pollution on hospitalization for respiratory disease in Taiyuan, China: A time-series analysis. International Journal of Environmental Research Public Health, 15(10), 2160.

    Article  CAS  Google Scholar 

  • Luong, L. M. T., Phung, D., Dang, T. N., et al. (2018). Seasonal association between ambient ozone and hospital admission for respiratory diseases in Hanoi. Vietnam. Plos ONE, 13(9), e0203751.

    Article  Google Scholar 

  • Ma, Y. X., Xiao, B. S., Liu, C., et al. (2016). Association between ambient air pollution and emergency room visits for respiratory diseases in spring dust season in Lanzhou, China. International Journal of Environmental Research and Public Health, 13(6), 613.

    Article  Google Scholar 

  • Ma, Y. X., Yang, S. X., Zhou, J. D., et al. (2018). Effect of ambient air pollution on emergency room admissions for respiratory diseases in Beijing. China. Atmospheric Environment, 191, 320–327.

    Article  CAS  Google Scholar 

  • Malig, B. J., Pearson, D. L., Chang, Y. B., et al. (2016). A time-stratified case-crossover study of ambient ozone exposure and emergency department visits for specific respiratory diagnoses in California (2005–2008). Environmental Health Perspectives, 124, 745–753.

    Article  CAS  Google Scholar 

  • Mihaltan, F., Deleanu, O., Nemes, R., & Ulmeanu, R. (2016). Air pollution and respiratory diseases: A problematic risk factor. Pneumologia, 65(3), 122–125.

    Google Scholar 

  • Nhung, N. T. T., Schindler, C., Dien, T. M., Probst-Hensch, N., Perez, L., & Künzli, N. (2018). Acute effects of ambient air pollution on lower respiratory infections in Hanoi children: An eight-year time series study. Environment International, 110, 139–148.

    Article  Google Scholar 

  • World Heath Organization (WHO). (2016). Ambient air pollution: a global assessment of exposure and burden of disease. Working Papers.

  • Palli, D., Sera, F., Giovannelli, L., et al. (2009). Environmental ozone exposure and oxidative DNA damage in adult residents of Florence, Italy. Environmental Pollution, 157(5), 1521–1525.

    Article  CAS  Google Scholar 

  • Phosri, A., Ueda, K., Phung, V. L. H., et al. (2019). Effects of ambient air pollution on daily hospital admissions for respiratory and cardiovascular diseases in Bangkok. Thailand. Science of the Total Environment, 651, 1144–1153.

    Article  CAS  Google Scholar 

  • Postma, D. S., Reddel, H. K., ten Hacken, N. H., & van den Berge, M. (2014). Asthma and chronic obstructive pulmonary disease: Similarities and differences. Clinical Chest Medicine, 35(1), 143–156.

    Article  Google Scholar 

  • Pride, K. R., Peel, J. L., Robinson, B. F., Busacker, A., Grandpre, J., et al. (2015). Association of short-term exposure to ground-level ozone and respiratory outpatient clinic visits in a rural location-Sublette County, Wyoming, 2008–2011. Environmental Research, 137, 1–7.

    Article  CAS  Google Scholar 

  • Qiu, H., Yu, I. T. S., Wang, X. R., et al. (2013). Season and humidity dependence of the effects of air pollution on COPD hospitalizations in Hong Kong. Atmospheric Environment, 76, 74–80.

    Article  CAS  Google Scholar 

  • Rodopoulou, S., Samoli, E., Chalbot, M. G., & Kavouras, I. G. (2015). Air pollution and cardiovascular and respiratory emergency visits in Central Arkansas: A time-series analysis. Science of the Total Environment, 536, 872–879.

    Article  CAS  Google Scholar 

  • Samet, J. M., Dominici, F., Zeger, S. L., et al. (2000). The national morbidity, mortality, and air pollution study. Part I: methods and methodological issues. Research Report of Health Effective Institution, 94, 5–14.

    CAS  Google Scholar 

  • Schraufnagel, D. E., Balmes, J. R., Cowl, C. T., et al. (2019). Air pollution and noncommunicable diseases: A review by the Forum of International Respiratory Societies’ Environmental Committee, Part 1: The damaging effects of air pollution. Chest, 155(2), 409–416.

    Article  Google Scholar 

  • Strosnider, H. M., Chang, H. H., Darrow, L. A., et al. (2019). Age-specific associations of ozone and fine particulate matter with respiratory emergency department visits in the United States. American Journal of Respiratory Critical Care Medicine, 199(7), 882–890.

    Article  CAS  Google Scholar 

  • Szyszkowicz, M., & Rowe, B. H. (2016). Respiratory health conditions and ambient ozone: A case-crossover study. Insights in Chest Diseases, 1, 10.

    Google Scholar 

  • Tang, X. Y., Li, J. L., Dong, Z. X., et al. (1989). Photochemical pollution in Lanzhou, China-A case study. Journal of Environmental Sciences, 58(1), 384–395.

    Google Scholar 

  • Tao, Y. B., Huang, W., Huang, X. L., et al. (2012). Estimated acute effects of ambient ozone and nitrogen dioxide on mortality in the pearl river delta of southern China. Environmental Health Perspectives, 120(3), 393–398.

    Article  CAS  Google Scholar 

  • Vahedian, M., Khanjani, N., Mirzaee, M., et al. (2017). Associations of short-term exposure to air pollution with respiratory hospital admissions in Arak. Iran. Journal of Environmental Health Science and Engineering, 15(1), 17.

    Article  Google Scholar 

  • Wang, Y. Y., Zu, Y. Q., Huang, L., et al. (2018). Associations between daily outpatient visits for respiratory diseases and ambient fine particulate matter and ozone levels in Shanghai. China. Environmental Pollution, 240, 754–763.

    Article  CAS  Google Scholar 

  • Winquist, A., Klein, M., Tolbert, P., et al. (2012). Comparison of emergency department and hospital admissions data for air pollution time-series studies. Environmental Health, 11, 70.

    Article  CAS  Google Scholar 

  • Wong, C. M., Atkinson, R. W., Anderson, H. R., et al. (2002). A tale of two cities: Effects of air pollution on hospital admissions in Hong Kong and London compared. Environmental Health Perspectives, 110(1), 67–77.

    Article  CAS  Google Scholar 

  • Wong, T. W., Tam, W. S., Yu, T. S., et al. (2002). Associations between daily mortalities from respiratory and cardiovascular diseases and air pollution in Hong Kong. China. Occupied Environmental Medicine, 59(1), 30–35.

    Article  CAS  Google Scholar 

  • Yang, C. Y., Chen, A., Chen, R. J., Qi, Y. Q., Ye, J. J., Li, S. M., Li, W. L., Liang, Z. J., Liang, Q., Guo, D. Q., et al. (2014). Acute effect of ambient air pollution on heart failure in Guangzhou, China. International Journal of Cardiology, 177(2), 436–441.

    Article  Google Scholar 

  • Yang, C. H., Yang, H. B., Guo, S., et al. (2012). Alternative ozone metrics and daily mortality in Suzhou: The China Air Pollution and Health Effects Study (CAPES). Science of the Total Environment, 426, 83–89.

    Article  CAS  Google Scholar 

  • Yang, J., Ou, C. Q., Song, Y. F., et al. (2016). Estimating years of life lost from cardiovascular mortality related to air pollution in Guangzhou, China. Science Total Environment, 573, 1566–1572.

    Article  CAS  Google Scholar 

  • Yang, Q. Y., Chen, Y., Shi, Y. L., Burnett, R. T., McGrail, K. M., & Krewski, D. (2003). Association between ozone and respiratory admissions among children and the elderly in Vancouver. Canada. Inhalation Toxicology, 15(13), 1297–1308.

    Article  CAS  Google Scholar 

  • Yunginger, J. W., Reed, C. E., O’Connell, E. J., et al. (1992). A community-based study of the epidemiology of asthma. Incidence rates, 1964–1983. American Revised Respiratory Diseases, 146(4), 888–894.

    Article  CAS  Google Scholar 

  • Zhang, F. X., Zhang, H., Wu, C. X., et al. (2021). Acute effects of ambient air pollution on clinic visits of college students for upper respiratory tract infection in Wuhan, China. Environmental Science and Pollution Research, 28(23), 29820–29830.

    Article  CAS  Google Scholar 

  • Zhang, Y., Wang, S. G., Ma, Y. X., Shang, K. Z., Cheng, Y. F., Li, X., Ning, G. C., Zhao, W. J., & Li, N. R. (2015). Association between ambient air pollution and hospital emergency admissions for respiratory and cardiovascular diseases in Beijing: A time series study. Biomedical and Environmental Sciences, 28(5), 352–363.

    CAS  Google Scholar 

  • Zhao, S. P., Yu, Y., & Qin, D. H. (2018). From highly polluted inland city of China to “Lanzhou Blue”: The air-pollution characteristics. Sciences in Cold and Arid Regions, 10(1), 0012–0026.

    Google Scholar 

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Funding

This research is supported by National Natural Science Foundation of China (Grant Nos. 41975141) and the Open Project Program of Shanghai Key. Laboratory of Meteorology and Health (QXJK201705).

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Yuxia Ma designed and carried out the research; Jiahui Shen set up models; Yifan Zhang, Hang Wang and Heping Li analyzed data; Yifan Cheng and Yongtao Guo assembled data; Yuxia Ma and Jiahui Shen wrote and revised the manuscript.

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Correspondence to Yuxia Ma.

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Ma, Y., Shen, J., Zhang, Y. et al. Short-term effect of ambient ozone pollution on respiratory diseases in western China. Environ Geochem Health 44, 4129–4140 (2022). https://doi.org/10.1007/s10653-021-01174-9

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  • DOI: https://doi.org/10.1007/s10653-021-01174-9

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