Abstract
Excessive fluoride intake has been reported in many studies, which can lead to diseases such as autism, mental retardation, low birth weight, reproductive disorder, as well as dental and bone fluorosis. The potential risk assessment of fluoride intake for the health of people living in Fars Province, Iran, is investigated. Hence, 1700 drinking water samples were taken from April 2018 to March 2020 in four seasons in 29 cities of Fars Province and were analyzed. Non-carcinogenic health risks of exposure to fluoride through drinking water were evaluated. Moreover, the spatial distribution maps of fluoride and hazard quotient (HQ) risk index were prepared using GIS software. The results showed that the concentration of fluoride in the drinking water of the studied area was in the range of 0.086 to 2.61 mg/L. Accordingly, in 48.27% of the cities, fluoride was in the range below the national and international standards, 34.48% of the cities were in the permissible range of 0.5 to 1.5 mg/L, and 17.24% of the urban areas of the province had fluoride contents above the permissible range. Hazard quotient index had the health risk of HQ > 1 in 27.58% of children, 17.24% of teenagers, and 10.34% of adults in the urban areas of Fars Province. In the cities with HQ > 1, there was risk of diseases associated with excessive fluoride intake. Therefore, it is necessary to replace water supply sources in these cities.
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Change history
12 July 2021
A Correction to this paper has been published: https://doi.org/10.1007/s10653-021-01029-3
References
Aghapour, S., Bina, B., Tarrahi, M. J., Amiri, F., & Ebrahimi, A. (2018). Distribution and health risk assessment of natural fluoride of drinking groundwater resources of Isfahan, Iran, using GIS. Environmental Monitoring and Assessment. https://doi.org/10.1007/s10661-018-6467-z
Amini, H., Haghighat, G. A., Yunesian, M., Nabizadeh, R., Mahvi, A. H., Dehghani, M. H., et al. (2016). Spatial and temporal variability of fluoride concentrations in groundwater resources of Larestan and Gerash regions in Iran from 2003 to 2010. Environmental Geochemistry and Health, 38(1), 25–37. https://doi.org/10.1007/s10653-015-9676-1
Amini, M., Mueller, K., Abbaspour, K. C., Rosenberg, T., Afyuni, M., Møller, K. N., et al. (2008). Statistical modeling of global geogenic fluoride contamination in groundwaters. Environmental Science & Technology, 42(10), 3662–3668. https://doi.org/10.1021/es071958y
AWWA. (2012). Standard Methods for examination of water and wastewater (22nd ed.). Washington: American Public Health Association Standard Methods. ISBN 978-087553-013-0.
Aslani, H., Zarei, M., Taghipour, H., Khashabi, E., Ghanbari, H., & Ejlali, A. (2019). Monitoring, mapping and health risk assessment of fluoride in drinking water supplies in rural areas of Maku and Poldasht, Iran. Environmental Geochemistry and Health, 41(5), 2281–2294. https://doi.org/10.1007/s10653-019-00282-x
Biswas, A. K., & Tortajada, C. (2019). Water crisis and water wars: Myths and realities. International Journal of Water Resources Development Routledge. https://doi.org/10.1080/07900627.2019.1636502
Cortés, A. S., Yohannessen, V. K., Tellerías, C. L., & Ahumada, P. E. (2019). Exposure to contaminants from coal-fired thermoelectric plants and children’s health: What is the international and national evidence? Revista Chilena De Pediatria, 90(1), 102–114. https://doi.org/10.32641/rchped.v90i1.748
de França, J. F., Pickler, T. B., Jozala, A. F., dos Santos, C. A., Batista, B. L., Pedron, T., et al. (2020). Determination of 17α-ethinylestradiol and toxic metals in surface waters, and estimation of daily intake. Environmental Monitoring and Assessment. https://doi.org/10.1007/s10661-019-7990-2
Dobaradaran, S., Khorsand, M., Hayati, A., Moradzadeh, R., Pouryousefi, M., & Ahmadi, M. (2018). Data on fluoride contents in groundwater of Bushehr province, Iran. Data in Brief, 17, 1158–1162. https://doi.org/10.1016/j.dib.2018.02.016
EPA. (2019). Integrated risk information system. United States Environmental Protection Agency.
Fayazi, F., Lak, R., & Nakhaei, M. (2007). Hydrogeochemistry and brine evolution of Maharlou Saline Lake, southwest of Iran. Carbonates and Evaporites, 22(1), 33–42. https://doi.org/10.1007/BF03175844
Gaafar, M., Mahmoud, S. H., Gan, T. Y., & Davies, E. G. R. (2020). A practical GIS-based hazard assessment framework for water quality in stormwater systems. Journal of Cleaner Production. https://doi.org/10.1016/j.jclepro.2019.118855
Ghanbarian, M., Ghanbarian, M., Hoseini, M., & Mahvi, A. H. (2014). Estimation of fluoride intake by Iranian powdered milk-fed infants. Fluoride, 47(4), 294–298.
Ghanbarian, M., Ghanbarian, M., Mahvi, A. H., & Tabatabaie, T. (2020). Enhanced fluoride removal over MgFe2O4–chitosan–CaAl nanohybrid: Response surface optimization, kinetic and isotherm study. International Journal of Biological Macromolecules, 148, 574–590. https://doi.org/10.1016/j.ijbiomac.2020.01.143
Ghanbarian, M., Nicknam, M. H., Mesdaghinia, A., Yunesian, M., Hassanvand, M. S., Soleimanifar, N., et al. (2019). Investigation and comparison of in vitro genotoxic potency of PM10 collected in rural and urban sites at Tehran in different metrological conditions and different seasons. Biological Trace Element Research, 189(1), 301–310. https://doi.org/10.1007/s12011-018-1469-9
Hajiouni, S., Dobaradaran, S., & Mahvi, A. H. (2019). Fluoride concentration in commercially available dairy milk in Iran. Fluoride Research, 52(4), 527–530.
Hasan, M. S. U., & Rai, A. K. (2020). Groundwater quality assessment in the Lower Ganga Basin using entropy information theory and GIS. Journal of Cleaner Production. https://doi.org/10.1016/j.jclepro.2020.123077
Havelaar, A. H., & Melse, J. M. (2003). Quantifying Public Health Risk in the WHO Guidelines for Drinking Water Quality. WHO RIVM report, Report number 734301022.
Hossain, M., & Ptra, P. K. (2020). Contamination zoning and health risk assessment of trace elements in groundwater through geostatistical modelling. Ecotoxicology and Environmental Safety. 189. https://doi.org/10.1016/j.ecoenv.2019.110038.
Hosseini, S., Mahvi, A., & Tsunodac, M. (2019). Fluoride content of coconut water and its risk assessment. Fluoride.
Hourieh Fallah, S., Bakaeian, M., Parsian, H., Amouei, A., Asgharnia, H., Ghanbarian, M., et al. (2020). Potentially harmful heavy metal contamination in Babolrood river: Evaluation for risk assessment in the Mazandaran province, Iran. International Journal of Environmental Analytical Chemistry, 00(00), 1–15. https://doi.org/10.1080/03067319.2020.1828386
Keramati, H., Miri, A., Baghaei, M., Rahimizadeh, A., Ghorbani, R., Fakhri, Y., et al. (2019). Fluoride in Iranian drinking water resources a systematic review meta-analysis and non-carcinogenic risk assessment. Biological Trace Element Research, 189, 261–273. https://doi.org/10.1007/s12011-018-1418-7.
Kisku, G. C., & Sahu, P. (2020). Fluoride contamination and health effects: An indian scenario. In Environmental Concerns and Sustainable Development (pp. 213–233). Springer Singaporehttps://doi.org/10.1007/978-981-13-5889-0_11
Kogan, F., Haddock, B., Fan, A., Jørgensen, N. R., Suetta, C., & Gold, G. E. (2019). [18F]-sodium fluoride imaging of bone metabolism after acute loading. Osteoarthritis and Cartilage, 27, S329–S330. https://doi.org/10.1016/j.joca.2019.02.735
Levallois, P., & Villanueva, C. M. (2019). Drinking water quality and human health: An editorial. International Journal of Environmental Research and Public Health. https://doi.org/10.3390/ijerph16040631
Mahvi, A., & Ghanbarian, M. (2012). Determination of fluoride concentration in powdered milk in Iran 2010. British Journal of nutrition, 107(4), 1077–1079. https://doi.org/10.1017/S0007114511003941.
Mesdaghinia, A., Vaghefi, K. A., Montazeri, A., Mohebbi, M. R., & Saeedi, R. (2010). Monitoring of fluoride in groundwater resources of Iran. Bulletin of Environmental Contamination and Toxicology, 84(4), 432–437. https://doi.org/10.1007/s00128-010-9950-y
Mohanta, V., Singh, S., & Mishra, B. (2020). Human health risk assessment of fluoride-rich groundwater using fuzzy-analytical process over the conventional technique. Groundwater for Sustainable Development, 10. https://doi.org/10.1016/j.gsd.2019.100291.
Sabol, J. (2020). Major analytical methods for determining lead in environmental and biological samples. Lead in Plants and the Environment, 1–13. https://doi.org/10.1007/978-3-030-21638-2_1.
Srivastava, S., & Flora, S. J. S. (2020). Fluoride in drinking water and skeletal fluorosis: A review of the global impact. Current Environmental Health Reports, 7, 140–146. https://doi.org/10.1007/s40572-020-00270-9.
Tayebi, L., & Sobhanardakani, S. (2020). Analysis of heavy metal contents and non-carcinogenic health risk assessment through consumption of tilapia fish (Oreochromis niloticus). Pollution, 6(1), 59–67. https://doi.org/10.22059/poll.2019.284500.639
Theurich, M. A., Humphreys, A. L., Gosselin, L. B., & Mccool-Myers, M. E. (2019). Food safety considerations for commercial complementary foods from global operational guidance on infant and young child feeding in emergencies. Nutrition Reviews. https://doi.org/10.1093/nutrit/nuy065
Wang, M., Liu, L., Li, H., Li, Y., Liu, H., Hou, C., et al. (2020). Thyroid function, intelligence, and low-moderate fluoride exposure among Chinese school-age children. Environment International. https://doi.org/10.1016/j.envint.2019.105229
WHO. (2008). Guidelines for drinking-water quality. Third Edition. ISBN 978 92 4 154761 1.
WHO. (2008). Guidelines for drinking-water quality: incorporating 1st and 2nd addenda. https://doi.org/10.1016/S1462-0758(00)00006-6.
Yousefi, M., Ghalehaskar, S., Asghari, F. B., Ghaderpoury, A., Dehghani, M. H., Ghaderpoori, M., & Mohammadi, A. A. (2019). Distribution of fluoride contamination in drinking water resources and health risk assessment using geographic information system, northwest Iran. Regulatory Toxicology and Pharmacology, 107, 104408. https://doi.org/10.1016/j.yrtph.2019.104408
Yousefi, M., Ghoochani, M., & Hossein Mahvi, A. (2018). Health risk assessment to fluoride in drinking water of rural residents living in the Poldasht city, northwest of Iran. Ecotoxicology and Environmental Safety, 148, 426–430. https://doi.org/10.1016/j.ecoenv.2017.10.057
Zhang, L., Zhao, L., Zeng, Q., Fu, G., Feng, B., Lin, X., et al. (2020). Spatial distribution of fluoride in drinking water and health risk assessment of children in typical fluorosis areas in north China. Chemosphere, 239. https://doi.org/10.1016/j.chemosphere.2019.124811.
Acknowledgements
The authors would like to thank the financial support (Grant #9890) of vice chancellery of research and technology, Shahroud University of Medical Sciences on this research.
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This research has been done by supporting of vice chancellery of research and technology, Shahroud University of Medical Sciences, Grant #9890.
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All authors contributed in this research as follow: Marjan Ghanbarian and Masoud Ghanbarian contributed in writing, software application, analysis of data and conceptualization of research, Tayebeh Tabatabaie, Maryam Ghanbarian and Seid-Kamal Ghadiri contributed in experimental works and methodology
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The original online version of this article was revised: The affiliation “Department of Environmental Engineering, Bushehr Branch, Islamic Azad University, Bushehr, Iran” was mistakenly included for the author “Marjan Ghanbarian”. The author is affiliated only with the affiliation “Environmental and Occupational Health Research Center, Shahroud University of Medical Sciences, Shahroud, Iran.
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Ghanbarian, M., Ghanbarian, M., Tabatabaie, T. et al. Distributing and assessing fluoride health risk in urban drinking water resources in Fars Province, Iran, using the geographical information system. Environ Geochem Health 44, 771–781 (2022). https://doi.org/10.1007/s10653-021-00982-3
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DOI: https://doi.org/10.1007/s10653-021-00982-3