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Inflammatory Bowel Disease-Related Abstracts Presented at National Conferences in the USA Are Frequently Unpublished as Full Manuscripts

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Abstract

Background

Numerous abstracts related to inflammatory bowel disease (IBD) are presented at national conferences in the USA. The overall rate of publication of these abstracts as complete manuscripts is unknown .

Methods

Abstracts submitted to the 2010 American College of Gastroenterology (ACG), Advances in Inflammatory Bowel Diseases (AIBD), and the American Gastroenterological Association abstracts at Digestive Disease Week (DDW) were reviewed. Each abstract was reviewed manually by two authors for type of research, study design, patient population, and outcome. Both PubMed and Google were then searched to determine whether the abstract was published as a full manuscript within five years of the conference. Univariate and multivariate logistic regression analysis was carried out using Stata 14.1.

Results

In total, 872 abstracts were reviewed. 49% (426/872) were published as complete manuscripts within five years of the conference. The average length of time to publication was 1.87 years (range 0–5). 42% of abstracts from ACG, 58% from AIBD, and 23% from DDW were eventually published (p < 0.0001). However, abstracts presented at DDW had the shortest time to publication compared to the other conferences (p = 0.002). Factors predictive of eventual publication include: number of authors (mean 7.5 for published vs 6.4 for unpublished p = 0.0001), clinical research compared to basic and translational (p = 0.026), and studies assessing drug safety with no adverse effects reported (p = 0.006).

Conclusion

Nearly 50% of the abstracts presented at major gastroenterology conferences in the USA are published as full manuscripts 5 years after the conference. Further studies are needed to assess why so many abstracts are not published.

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Authors contributions

Dr. JDF and Dr. ASC had full access to all of the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis. JDF is a guarantor of the article; JDF, ASC took part in study concept and design; JDF, PS, EB, VR, VRM participated in acquisition of data; JDF, PS, ASC contributed to analysis and interpretation of data; JDF, PS, ASC took part in drafting of the manuscript; JDF, ASC, PS contributed to critical revision of the manuscript for important intellectual content; PS participated in statistical analysis; JDF, ASC took part in study supervision; each author has approved the final draft of this manuscript.

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Authors and Affiliations

  1. Division of Gastroenterology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, 110 Francis St, 8E Gastroenterology, Boston, MA, 02215, USA

    Joseph D. Feuerstein, Priya Sehgal, Varun Rao, Emily Baroni & Adam S. Cheifetz

  2. Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA

    Vijayram Reddy Malladi

Authors
  1. Joseph D. Feuerstein
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  2. Priya Sehgal
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  3. Varun Rao
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  4. Vijayram Reddy Malladi
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  5. Emily Baroni
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  6. Adam S. Cheifetz
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Corresponding author

Correspondence to Joseph D. Feuerstein.

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Conflict of interest

None of the authors have any relevant conflicts of interest related to this manuscript. In full disclosure, the following industry relationships are noted: Dr. Adam Cheifetz: Consulting or Grants from the following: (1) Abbott Laboratories, (2) Janssen Pharaceuticals, (3) Warner-Chilcott, (4) Given Imaging, (5) Prometheus Labs, (6) Pfizer.

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Joseph D. Feuerstein and Priya Sehgal are equal first authors.

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Feuerstein, J.D., Sehgal, P., Rao, V. et al. Inflammatory Bowel Disease-Related Abstracts Presented at National Conferences in the USA Are Frequently Unpublished as Full Manuscripts. Dig Dis Sci 62, 352–357 (2017). https://doi.org/10.1007/s10620-016-4394-9

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  • DOI: https://doi.org/10.1007/s10620-016-4394-9

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