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Prevalence of Colon Polyps Detected by Colonoscopy Screening of Asymptomatic Hispanic Patients

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Abstract

Background

Compared with whites, Hispanics have lower incidence of and mortality from colorectal cancer. The purpose of this study was to determine whether asymptomatic Hispanics undergoing colonoscopy screening also have lower age-adjusted incidence of polyps ≥10 mm. Such data could be used to formulate future screening guidelines.

Aims

The objectives of this study were to measure and analyze the prevalence and location of polyps sized ≥10 mm in asymptomatic white and Hispanic patients who received colonoscopy screening.

Methods

Colonoscopy data were prospectively collected from the Clinical Outcomes Research Initiative database, which includes data from a consortium of 66 adult gastrointestinal practice sites in the United States. Asymptomatic white (n = 146,798) and Hispanic (n = 7,654) patients who received colonoscopy screening from 2004 to 2007 were identified. The prevalence of any polyps ≥10 mm and of proximal polyps ≥10 mm was adjusted for age, sex, practice site type, and family history of colorectal cancer in a multivariate analysis.

Results

There was no significant difference between prevalence of polyps ≥10 mm in Hispanic and white patients (5.8% vs. 6.2%; P = 0.11; adjusted OR 0.94; 95% CI 0.85–1.03). There was also no significant difference between prevalence of proximal polyps ≥10 mm in Hispanics and whites (adjusted OR 1.05; 95% CI 0.87–1.27).

Conclusion

Despite lower incidence of colorectal cancer, the risk of polyps ≥10 mm for Hispanic patients undergoing colonoscopy screening is similar to that for whites. These data emphasize the importance of encouraging timely colorectal cancer screening in Hispanics. Our findings support the application of similar recommendations for colorectal cancer screening of Hispanics and whites.

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Acknowledgments

This project was supported with funding from NIDDK UO1 DK57132. In addition, the practice network (Clinical Outcomes Research Initiative; CORI) has received support from the following entities to support the infrastructure of the practice-based network: AstraZeneca, Bard International, Pentax USA, ProVation, Endosoft, GIVEN Imaging, and Ethicon. The commercial entities had no involvement in this research. Dr Lieberman is the executive director of the CORI, a non-profit organization that receives funding from federal and industry sources. The CORI database was used in this study. This relationship was reviewed and managed by the OHSU and VA Conflict of Interest in Research Committees.

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Authors and Affiliations

  1. Oregon Health & Science University, 3181 SW Sam Jackson Park Road, PV-310, Portland, OR, 97239, USA

    Brent Lee, Jennifer Holub, Dawn Peters & David Lieberman

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  1. Brent Lee
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  2. Jennifer Holub
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  3. Dawn Peters
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  4. David Lieberman
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Corresponding author

Correspondence to Brent Lee.

Appendix

Appendix

See Table 7.

Table 7 Pathology verification of the surrogate outcome [16]
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Lee, B., Holub, J., Peters, D. et al. Prevalence of Colon Polyps Detected by Colonoscopy Screening of Asymptomatic Hispanic Patients. Dig Dis Sci 57, 481–488 (2012). https://doi.org/10.1007/s10620-011-1898-1

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  • DOI: https://doi.org/10.1007/s10620-011-1898-1

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