A new ferulic acid derivative, (1R,2R)-2-O-E-feruloyl-1-(4-hydroxyphenyl)butane-1,2-diol (1) together with six known compounds (2–7), was isolated from the extracts of Pimpinella thellungiana H.Wolff. The structures of compounds were identified by MS, NMR spectroscopy, NMR calculation, ECD, and comparisons of spectroscopic data. Compounds 1–7 were further evaluated for their anti-inflammatory activities on LPS-induced RAW 264.7 cells.
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R. Liu, G. Tai, R. Wang, S. R. Zhang, and M. R. Pei, J. Chin. Med. Mater., 44 (2), 363 (2021).
G. J. Chen, R. M. Xie, Y. Q. Shen, A. R. Miao, D. H. Wang, Q. Y. Xu, and S. D. Ma, Shaanxi Med. J., 8, 48 (1982).
H. F. Wang and J. Y. Wen, Guangdong Feed, 31 (5), 28 (2022).
Chinese Pharmacopoeia Commission, Pharmacopoeia of the People′s Republic of China, China Medical Science Press, Beijing, 2020.
Z. G. Jin and M. S. Wang, J. Shangluo Univ., 5, 43 (2008).
X. M. Cui, H. Ren, J. Hu, J. Chen, Z. Y. Mao, and Z. Y. Chen, Lishizhen Med. Mater. Med. Res., 31 (10), 2313 (2020).
K. Kuck, A. Unterholzner, B. Lipowicz, S. Schwindl, G. Jurgenliemk, T. J. Schmidt, and J. Heilmann, Molecules, 28 (4), 1637 (2023).
Z. Dai, F. Wang, G. L. Wang, and R. C. Lin, China J. Chin. Mater. Med., 21, 1798 (2006).
F. Tomoyuki, F. Atsunori, and N. Mitsuru, Phytochemistry, 37, 543 (1994).
S. J. In, K. H. Seo, N. Y. Song, D. S. Lee, Y. C. Kim, and N. I. Baek, Arch. Pharm. Res., 38 (1), 26 (2015).
Y. Yu, H. Gao, Y. Dai, X. Y. Li, J. M. Li, and X. S. Yan, Chin. Tradit. Herb. Drugs, 41 (4), 509 (2010).
Y. S. F, S. X. Liu, Y. C. Ma, J. W. Dong, L. Cai, and Z. T. Ding, Nat. Prod. Res., 31 (1), 70 (2017).
G. J. Kang, S. J. Yang, H. Y. Zhou, Z. M. Yang, and L. Y. Chen, J. Chin. Med. Mater., 37 (1), 74 (2014).
Y. G. Cheng, J. Y. Tan, L. J. Li, S. H. Wang, K. L. Liu, J. M. Wang, and Y. L. Wang, Nat. Prod. Res., 36 (21), 5449 (2022).
Acknowledgment
The work was supported by the Science and Technology Innovation Plan Project of the Shanxi Provincial Department of Education (2021L359), Shanxi Provincial Science and Technology Innovation Talent Team (202204051002028), scientific and technological innovation team of Shanxi University of Chinese Medicine (2022TD1015). This research was also supported by the funding of Shanxi University of Traditional Chinese Medicine′s discipline construction (2023XKJS-26). Development of new preparation technology for external use of traditional Chinese medicine supported by Key Laboratory of Health Commission of Shanxi Province (2021SYS23).
In addition, J. Y. Tan and J. L. Li contributed equally to this work.
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Published in Khimiya Prirodnykh Soedinenii, No. 6, November–December, 2023, pp. 919–921.
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Tan, J.Y., Li, J.L., Li, P. et al. A New Ferulic Acid Derivative from Pimpinella thellungiana. Chem Nat Compd 59, 1088–1091 (2023). https://doi.org/10.1007/s10600-023-04202-5
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DOI: https://doi.org/10.1007/s10600-023-04202-5