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Chromone Derivatives from Whole Plants of Chamaecrista rotundifolia and their Antibacterial Activity

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Chemistry of Natural Compounds Aims and scope

In our search for new bioactive metabolites from plants of Cassia genus, the phytochemical investigation on the whole plants of C. rotundifolia was carried out, and that led to the isolation of two new (1 and 2) and five known (3–7) chromones. Their structures were elucidated by spectroscopic methods, including extensive 1D and 2D NMR techniques. Interestingly, 1 and 2 showed good anti-methicillin-resistant Staphylococcus aureus (anti-MRSA) activities with IZD of 13.2 ± 2.4 and 15.8 ± 2.6 mm, respectively.

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Acknowledgment

This project was supported financially by the Foundation of Yunnan Basic Research Program (No. 2019FD119), the Yunnan Applied Basic Research Projects for Excellent Young Scholars (202001AW070002), the Candidates of the Young and Middle Aged Academic Leaders of Yunnan Province (2019HB016) and Yunnan Innovative Research Team (2019HC020).

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Authors and Affiliations

  1. Key Laboratory of Natural Products Synthetic Biology of Ethnic Medicinal, State Ethnic Affairs Commission, Yunnan Minzu University, 650504, Kunming, P. R. China

    Pei-Song Yang, Xin-Yan He, De-Quan Huang, Shan-Shan Li, Si-Yu Shen, Xiao-Shan Liu, Yue-Yu Ma, Dong Miao, Min Zhou & Yin-Ke Li

  2. School of Animal Science and Technology, Southwest University, 400715, Chongqing, P. R. China

    Xin-Yan He & Yue-Yu Ma

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  1. Pei-Song Yang
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  9. Min Zhou
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Correspondence to Min Zhou or Yin-Ke Li.

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Published in Khimiya Prirodnykh Soedinenii, No. 3, May–June, 2023, pp. 388–391.

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Yang, PS., He, XY., Huang, DQ. et al. Chromone Derivatives from Whole Plants of Chamaecrista rotundifolia and their Antibacterial Activity. Chem Nat Compd 59, 458–461 (2023). https://doi.org/10.1007/s10600-023-04023-6

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  • DOI: https://doi.org/10.1007/s10600-023-04023-6

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