New Δ2,3-steroids that were practicable promising precursors of natural steroidal compounds were synthesized by targeted sonochemical deoxygenation of ecdysteroid mesylates that were derivatives of 20-hydroxyecdysone. The structures of the synthesized compounds and the configuration of the atoms were established using 1D and 2D 1H NMR and 13C NMR. The empirical compositions were confirmed by measuring their masses using HR-MS.
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Acknowledgment
The work was financially supported by the Russian Foundation for Basic Research (RFBR, Grant No. 20-03-00649). A part of the research was performed on Federal Program No. FMRS-2022-0081.
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Translated from Khimiya Prirodnykh Soedinenii, No. 1, January–February, 2023, pp. 90–94.
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Savchenko, R.G., Limantseva, R.M. & Odinokov, V.N. Deoxygenation of Ecdysteroid Mesylates by Sonication. Chem Nat Compd 59, 102–106 (2023). https://doi.org/10.1007/s10600-023-03927-7
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DOI: https://doi.org/10.1007/s10600-023-03927-7