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Aspergillines K and L, Two New Anti-TMV Indole Alkaloids from Fungus Aspergillus versicolor Derived from Tobacco

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Chemistry of Natural Compounds Aims and scope

Two new (1 and 2) and four known (3–6) CPA-type indole alkaloids were isolated from the fungus Aspergillus versicolor. Their structures were determined by means of HR-ESI-MS and extensive 1D and 2D NMR spectroscopic studies. Compounds 1 and 2 were tested for their anti-tobacco mosaic virus (anti-TMV) activity. The results showed that compounds 1 and 2 demonstrated potential anti-TMV activity with inhibition rates within the range 29.2 and 30.1% respectively.

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Acknowledgment

This project was supported by the National Natural Science Foundation of China (No. 21967021), the Yunnan Applied Basic Research Projects for Excellent Young Scholars (grant to M.Z.), and the Foundation of Yunnan Innovative Research Team (2019HC020).

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Authors and Affiliations

  1. Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education, Yunnan Minzu University, 650031, Kunming, P. R. China

    Ya-Ning Zhu, Ming-Xin Liu, Man-Fei Li, Hua-Shun Liu, Min Zhou, Qiu-Fen Hu & Yin-Ke Li

  2. Key Laboratory of Tobacco Chemistry of Yunnan Province, China Tobacco Yunnan Industrial Co., Ltd., 650231, Kunming, P. R. China

    Bing-Biao Cai, Yong Li, Guang-Yu Yang, Yin-Ke Li & Xue-Mei Li

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  1. Ya-Ning Zhu
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  2. Ming-Xin Liu
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  3. Bing-Biao Cai
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  4. Yong Li
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  5. Man-Fei Li
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  6. Hua-Shun Liu
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  7. Min Zhou
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  8. Guang-Yu Yang
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  9. Qiu-Fen Hu
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  10. Yin-Ke Li
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  11. Xue-Mei Li
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Corresponding authors

Correspondence to Yin-Ke Li or Xue-Mei Li.

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Published in Khimiya Prirodnykh Soedinenii, No. 4, July–August, 2022, pp. 603–606.

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Zhu, YN., Liu, MX., Cai, BB. et al. Aspergillines K and L, Two New Anti-TMV Indole Alkaloids from Fungus Aspergillus versicolor Derived from Tobacco. Chem Nat Compd 58, 712–716 (2022). https://doi.org/10.1007/s10600-022-03774-y

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  • DOI: https://doi.org/10.1007/s10600-022-03774-y

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