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Antimicrobial Secondary Metabolites from the Marine-Derived Actinomycete Nocardiopsis synnemataformans HT06

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Analysis of an antimicrobial extract prepared from the culture broth of the marine-derived actinomycete Nocardiopsis synnemataformans (HT06 strain) led to the isolation of a new C-glucoside benzoic acid derivative, 4βC-glucopyranosyl-3,5-dihydroxy-2-methoxybenzoic acid (1), along with eight known compounds, norharman (2), (E)-4-(3-hydroxy-4-methoxyphenyl)but-3-en-2-one (3), methyl 2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate (4), 1H-indole-3-ethanol (5), 4-hydroxy-3-methoxybenzaldehyde (6), 3-phenylpropanoic acid (7), phloretic acid (8), and cinnamic acid (9). The antimicrobial activity of all isolated compounds was assayed.

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Acknowledgment

The authors would like to express their thanks for the grant and financial support received from the Vietnam Academy of Science and Technology (Grant No. VAST02.05/19-20).

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Authors and Affiliations

  1. Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), Hanoi, Vietnam

    Vu Thi Quyen, Le Thi Hong Minh, Vu Thi Thu Huyen, Nguyen Mai Anh, Nguyen Thi Hue, Phi Thi Dao, Nguyen Thuy Linh, Pham Van Cuong & Doan Thi Mai Huong

  2. Faculty of Chemistry, Graduate University of Science and Technology, VAST, Hanoi, Vietnam

    Pham Van Cuong & Doan Thi Mai Huong

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  1. Vu Thi Quyen
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  2. Le Thi Hong Minh
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  3. Vu Thi Thu Huyen
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  4. Nguyen Mai Anh
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  5. Nguyen Thi Hue
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  6. Phi Thi Dao
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  7. Nguyen Thuy Linh
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  8. Pham Van Cuong
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  9. Doan Thi Mai Huong
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Correspondence to Doan Thi Mai Huong.

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Published in Khimiya Prirodnykh Soedinenii, No. 4, July–August, 2022, pp. 597–599.

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Quyen, V.T., Minh, L.T.H., Huyen, V.T.T. et al. Antimicrobial Secondary Metabolites from the Marine-Derived Actinomycete Nocardiopsis synnemataformans HT06. Chem Nat Compd 58, 704–707 (2022). https://doi.org/10.1007/s10600-022-03772-0

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  • DOI: https://doi.org/10.1007/s10600-022-03772-0

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