A new constituent, named (4R)-6′′′′ -O-sinapoylpueroside B (1), was isolated from the dried roots of Pueraria lobata (Willd.) Ohwi. The structure of 1 was identified by HR-ESI-MS, UV, IR, 1D NMR, 2D NMR, and CD spectra. Compound 1 was evaluated for the inhibitory activity against PTP1B in vitro and showed no obvious activity.
Similar content being viewed by others
References
Y. G. Sun, S. S. Wang, J. T. Feng, X. Y. Xue, and X. M Liang, J. Asian Nat. Prod. Res., 10 (8), 719 (2008).
C. B. Fang, X. C. Wan, C. J. Jiang, and H. Q. Cao, JPC.-J. Planar. Chromat., 18 (101), 73 (2005).
Chinese Pharmacopoeia Commission, Pharmacopoeia of the People′s Republic of China, Chinese Medicine Science and Technology, Beijing, 2020, Part 1, 347 pp.
Y. H. Choi, S. S. Hong, Y. S. Shin, B. Y. Hwang, S. Y. Park, and D. Lee, Arch. Pharm. Res., 33 (10), 1651 (2010).
S. E. Jin, Y. K. Son, B. S. Min, H. A. Jung, and J. S. Choi, Arch. Pharm. Res., 35 (5), 823 (2012).
Y. J. Sun, H. M. Zhang, M. Cheng, S. J. Cao, M. Qiao, B. L. Zhang, L. Q. Ding, and F. Qiu, Nat. Prod. Res., 33 (24), 3485 (2019).
X. X. Wang, J. Wu, H. Chiba, K. Umegaki, K. Yamada, and Y. Ishimi, J. Bone. Miner. Metab., 21 (5), 268 (2003).
T. Nohara, J. Kinjo, J. Furusawa, Y. Sakai, M. Inoue, Y. Shirataki, Y. Ishibashi, I. Yokoe, and M. Komatsu, Phytochemistry, 33, 1207 (1993).
R. Sun, X. X. Deng, D. D. Zhang, F. Z. Xie, D. Wang, J. T. Wang, M. S. Tavallaie, F. Q. Jiang, and L. Fu, Bioorg. Chem., 87, 12 (2019).
J. H. He, L. X. Chen, and H. Li, Fitoterapia, 134, 270 (2019).
J. B. Sun, J. Xu, S. Wang, Z. D. Hou, X. C. Lu, L. P. An, and P. G. Du, Fitoterapia, 138, 104342 (2019).
ACKNOWLEDGMENT
This work was financially supported by National Key Research and Development Project (No. 2017YFC1702902).
Author information
Authors and Affiliations
Corresponding authors
Additional information
Published in Khimiya Prirodnykh Soedinenii, No. 4, July–August, 2022, pp. 515–517.
Rights and permissions
Springer Nature or its licensor holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.