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A New β-Ionone from Liriodendron tulipifera

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Chemistry of Natural Compounds Aims and scope

A new β-ionone, litulipiferic acid (12), was isolated from the leaves of Liriodendron tulipifera (Magnoliaceae). The structure of the new β-ionone was elucidated by chemical and physical evidence. The anticancer effect of compounds 1–3, 5, 6, and 8 on A375 cells exhibit a dose-dependent behavior. When cells were exposed to epitulipinolide diepoxide (8) at 100 μM, the data exhibited viabilities of less than 25% after 24 h of treatment.

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Acknowledgment

This investigation was supported by a grant from the Ministry of Science and Technology, Taiwan (Grant MOST 109-2221-E-005-012). We also thank the ENABLE Projects of National Chung Hsing University (ENABLE: 110ST001G).

Author information

Authors and Affiliations

  1. School of Medical and Health Sciences, Fooyin University, 83102, Kaohsiung, Taiwan

    C. Y. Chen & H. C. Yeh

  2. School of Medicine, Yichun University, 576 XueFu Road, Yuanzhou District, 336000, Yichun, P. R. China

    C. M. Liu

  3. School of Nursing, Fooyin University, 83102, Kaohsiung, Taiwan

    W. J. Li

  4. Department of Medical Laboratory Science and Biotechnology, Fooyin University, 83102, Kaohsiung, Taiwan

    H. T. Li

  5. Bioresource Collection and Research Center (BCRC), Food Industry Research and Development Institute (FIRDI), Hsinchu, 300, Taiwan

    M. J. Cheng

  6. Department of Obstetrics and Gynecology, Chung-Kang Branch, Cheng Ching Hospital, Taichung, 407, Taiwan

    P. C. Hsieh

  7. Ph.D. Program in Tissue Engineering and Regenerative Medicine, National Chung Hsing University, Taichung, 402, Taiwan

    H. M. Wang

  8. Graduate Institute of Biomedical Engineering, National Chung Hsing University, Taichung, 402, Taiwan

    H. M. Wang

  9. Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, 807, Kaohsiung, Taiwan

    H. M. Wang

  10. Department of Medical Laboratory Science and Biotechnology, China Medical University, Taichung, 404, Taiwan

    H. M. Wang

Authors
  1. C. Y. Chen
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  2. C. M. Liu
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  3. H. C. Yeh
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  4. W. J. Li
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  5. H. T. Li
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  6. M. J. Cheng
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  7. P. C. Hsieh
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  8. H. M. Wang
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Corresponding authors

Correspondence to C. Y. Chen, H. T. Li, P. C. Hsieh or H. M. Wang.

Additional information

Published in Khimiya Prirodnykh Soedinenii, No. 3, May–June, 2022, pp. 390–393.

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Chen, C.Y., Liu, C.M., Yeh, H.C. et al. A New β-Ionone from Liriodendron tulipifera. Chem Nat Compd 58, 455–458 (2022). https://doi.org/10.1007/s10600-022-03708-8

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  • DOI: https://doi.org/10.1007/s10600-022-03708-8

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