One new phenyl group dimeric compound, named polygamol A (1), together with two known compounds, 2,2-bis[4-(2,3-dihydroxypropoxy)phenyl]propane (2) and 1,3-di-O-[2′,2′-di-(p-phenylene)isopropylidene]-glycerol (3), were isolated from the roots of Polygonum amplexicaule var. sinense. The structures of these compounds were elucidated based on spectroscopic analysis. The new compound exhibited weak activity in vitro against the MGC-803, A549, SMMC-7721, and HT-29 cell lines.
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Acknowledgment
This research was financially supported by the construct program of the key discipline of Chinese Pharmacy in Hunan Province (Xiangjiaotong [2011] 76); Science and technology tackling and major scientific and technological achievements conversion projects of strategic emerging industries in Hunan Province, China (No. 2018GK4027); Hunan University of Chinese Medicine, Open Fund of Hunan Provincial Research Center for Standardization and Functional Engineering Technology of Traditional Chinese Medicine Pieces in 2018 (No. 2018-2-3), and Natural Science Foundation of Hunan Province (2018JJ2300). Guang-ming Xu and Fan Zhao contributed equally to this work.
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Published in Khimiya Prirodnykh Soedinenii, No. 6, November–December, 2020, pp. 917–919.
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Xu, Gm., Zhao, F., Liu, F. et al. A New Compound from Polygonum amplexicaule var. sinense. Chem Nat Compd 56, 1068–1071 (2020). https://doi.org/10.1007/s10600-020-03228-3
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DOI: https://doi.org/10.1007/s10600-020-03228-3