A new 27-norcucurbitane triterpenoid, 5β,19-epoxy-3β-hydroxy-19(R)-methoxy-27-norcucurbita-6,23(E)-dien-25-one (1), was isolated from the fruits of Momordica charantia var. abbreviata. Its structure was elucidated by spectroscopic analyses including 1D and 2D NMR (1H, 13C, COSY, HMQC, HMBC, and NOESY) and comparison with the data of known analogues.
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N. Y. Chiu and K. H. Chang, The Illustrated Medicinal Plants of Taiwan, Vol. 4, SMC Publishing Inc, Taiwan, 1995, p. 213.
S. J. Wu and L. T. Ng, LWT-Food Sci. Technol., 41, 323 (2008).
Y. L. Lu, Y. H. Liu, J. H. Chyuan, K. T. Cheng, W. L. Liang, and W. C. Hou, Bot. Stud., 53, 207 (2012).
C. K. Lii, H. W. Chen, W. T. Yun, and K. L. Liu, J. Ethnopharmacol., 122, 227 (2009).
C. Hsu, T. H. Tsai, Y. Y. Li, W. H. Wu, C. J. Huang, and P. J. Tsai, Food Chem., 135, 976 (2012).
T. H. Tsai, W. C. Huang, H. T. Ying, Y. H. Kuo, C. C. Shen, Y. K. Lin, and P. J. Tsai, Molecules, 21, 454 (2016).
Y. L. Lu, Y. H. Liu, W. L. Liang, J. H. Chuang, K. T. Cheng, H. J. Liang, and W. C. Hou, Bot. Stud., 52, 427 (2011).
E. S. Chipps, R. Jayini, S. Ando, A. D. Protzman, M. Z. Muhi, M. A. Mottaleb, A. Malkawi, and M. R. Islam, Nat. Prod. Commun., 7, 1203 (2012).
W. Kuanhuta, T. Aree, S. Pornpakakul, and P. Sawasdee, Nat. Prod. Commun., 9, 765 (2014).
C. Y. Chao and C. J. Huang, J. Biomed. Sci., 10, 782 (2003).
Y. W. Liao, C. R. Chen, J. L. Hsu, Y. S. Lin, H. L. Cheng, W. L. Shih, Y. H. Kuo, and C. I. Chang, Nat. Prod. Commun., 8, 79 (2013).
C. R. Chen, Y. W. Liao, Y. H. Kuo, J. L. Hsu, and C. I. Chang, Nat. Prod. Commun., 12, 1013 (2017).
D. A. Mulholland, J. V. Sewram, R. Osborne, K. H. Pegel, and J. D. Connolly, Phytochemistry, 45, 391 (1997).
Y. Kimura, T. Akihisa, N. Yuasa, M. Ukiya, T. Suzuki, M. Toriyama, Motohashi, and H. Tokuda, J. Nat. Prod., 68, 807 (2005).
Acknowledgment
This research was supported by grants from the Ministry of Science and Technology, Taiwan (MOST 105-2320-B-020-002-MY3 and NSC 102-2313-B-020-010-MY3). We thank Ms. Shu-Yun Sun and Ms. Lih-Mei Sheu for the MS measurements in the Instrumentation Center of the College of Science, National Taiwan University and National Chung Hsing University.
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Published in Khimiya Prirodnykh Soedinenii, No. 4, July–August, 2020, pp. 595–597.
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Chen, CR., Liao, YW., Hsu, JL. et al. A New 27-Norcucurbitane Triterpenoid from the Fruits of Momordica charantia var. abbreviata. Chem Nat Compd 56, 688–691 (2020). https://doi.org/10.1007/s10600-020-03120-0
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DOI: https://doi.org/10.1007/s10600-020-03120-0