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A New Eremophilane Sesquiterpene with Nematocidal Activity from Ligularia veitchiana

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Chemistry of Natural Compounds Aims and scope

A new eremophilane sesquiterpene, 10α-hydroxy-3-oxoeremophil-1(2),7(11),8(9)-trien-8(12)-olide (1), was isolated from Ligularia veitchiana. The structure of the new compound was elucidated by physical and spectroscopic data analysis, including 1D NMR and 2D NMR and HR-ESI-MS. Compound 1 showed inhibitory activity against the second-stage juveniles (J2) of Meloidogyne incognita with an LC50 value of 134.5 mg/L.

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Acknowledgment

This work was supported by the National Science Foundation of China (Grant No. 31570407) and the National College Students Innovation and Entrepreneurship Training Program (Grant No. GCCX2018110011).

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Authors and Affiliations

  1. College of Life and Environmental Science, Minzu University of China, 100081, Beijing, P. R. China

    Hai-bo Wu, Ting-ting Liu, Wen-jie Deng, Jing Zhang & Luo-wenlei Yang

  2. Beijing Engineering Research Center of Food Environment and health, Minzu University of China, 100081, Beijing, P. R. China

    Hai-bo Wu

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  1. Hai-bo Wu
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  2. Ting-ting Liu
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  3. Wen-jie Deng
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  4. Jing Zhang
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  5. Luo-wenlei Yang
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Correspondence to Hai-bo Wu.

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Published in Khimiya Prirodnykh Soedinenii, No. 4, July–August, 2019, pp. 576–577.

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Wu, Hb., Liu, Tt., Deng, Wj. et al. A New Eremophilane Sesquiterpene with Nematocidal Activity from Ligularia veitchiana. Chem Nat Compd 55, 671–673 (2019). https://doi.org/10.1007/s10600-019-02775-8

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  • DOI: https://doi.org/10.1007/s10600-019-02775-8

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