Reactions of quinoxalines and quinoxalin-2-ones with C-nucleophiles under acid-catalysis conditions gave products from nucleophilic substitution of hydrogen. Substitution of F atoms in the aromatic core of quinoxalines was studied. Antibacterial and fungistatic activity of the synthesized compounds was studied.
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We thank the RFBR (Grants 18-33-00727 mol_a and 18-03-00715 A) for sponsoring the research.
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Translated from Khimiya Prirodnykh Soedinenii, No. 3, May–June, 2019, pp. 441–447.
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Azev, Y.A., Koptyaeva, O.S., Tsmokalyuk, A.N. et al. Synthesis of Natural and Biologically Active Quinoxaline Analogs. Chem Nat Compd 55, 513–519 (2019). https://doi.org/10.1007/s10600-019-02728-1
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DOI: https://doi.org/10.1007/s10600-019-02728-1