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Phytotoxic Secondary Metabolites from the Endolichenic Fungus Myxotrichum sp.

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Chemistry of Natural Compounds Aims and scope

One new macrolide myxotrilactone A (1), along with six known compounds (2–7), were isolated from the extract of solid-substrate cultures of the endolichenic fungus Myxotrichum sp. by various chromatography methods. The planar structure of compound 1 was determined by HR-ESI-MS and NMR data, and its relative and absolute configurations were established by NOESY experiment and comparison with the known compound 2. Selected isolates were evaluated for their allelopathic activities, and compounds 1 and 2 significantly retarded shoot elongation of Arabidopsis thaliana.

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Acknowledgment

This work was financially supported by the National Natural Science Foundation of China (No. 31400110), the PUMC Youth Fund and the Fundamental Research Funds for the Central Universities (No. 3332015146), the Program for Innovative Research Team in IMPLAD (IT1305), and the Special Fund for Basic Scientific Research from Yunnan Branch of IMPLAD at CAMS & PUMC (YZYN-15-03).

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Authors and Affiliations

  1. Institute of Medicinal Plant Development, Yunnan Branch, Chinese Academy of Medical Sciences and Peking Union Medical College, 666100, Jinghong, P. R. China

    Chao Yuan

  2. Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, 100193, Beijing, P. R. China

    Gang Ding, Yuhua Guo, Xiaojun Ma & Zhongmei Zou

  3. College of Life Sciences, Shandong Normal University, No. 88 East Wenhua Road, 250014, Jinan, P. R. China

    Haiying Wang

Authors
  1. Chao Yuan
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  2. Gang Ding
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  3. Haiying Wang
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  4. Yuhua Guo
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  5. Xiaojun Ma
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  6. Zhongmei Zou
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Corresponding authors

Correspondence to Xiaojun Ma or Zhongmei Zou.

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Published in Khimiya Prirodnykh Soedinenii, No. 4, July–August, 2018, pp. 542–544.

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Yuan, C., Ding, G., Wang, H. et al. Phytotoxic Secondary Metabolites from the Endolichenic Fungus Myxotrichum sp.. Chem Nat Compd 54, 638–641 (2018). https://doi.org/10.1007/s10600-018-2435-7

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  • DOI: https://doi.org/10.1007/s10600-018-2435-7

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