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Reaction of 5-Hydroxymethyl-6-Methyluracil with Toluenesulfonyl Chloride or Methanesulfonyl Chloride and Tertiary Amines

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Quaternary ammonium salts were formed or the starting uracil was recovered after the reaction of 5-hydroxymethyl-6-methyluracil with toluenesulfonyl chloride or methanesulfonyl chloride and tertiary amines.

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References

  1. A. R. Gimadieva, V. A. Myshkin, A. G. Mustafin, Yu. N. Chernyshenko, N. S. Borisova, Yu. S. Zimin, and I. B. Abdrakhmanov, Khim.-farm. Zh., 48, 25 (2014).

    Google Scholar 

  2. M. Hanus, M. Kabelac, D. Nachtigallova, and P. Hobza, Biochemistry, 44, 1701 (2005).

    Article  CAS  PubMed  Google Scholar 

  3. M. S. Novikov and N. Geisman, Khim. Geterotsikl. Soedin., 1537 (2013).

  4. A. Palasz and D. Ciez, Eur. J. Med. Chem., 97, 582 (2015).

    Article  CAS  PubMed  Google Scholar 

  5. N. V. Lazarev and G. I. Felistovich, Pentoxyl and Its Application to Aleukia [in Russian], MedGIZ, Leningrad, 1954, p. 120.

    Google Scholar 

  6. V. A. Myshkin and A. B. Bakirov, Hydroxymethyluracil (Outline of Experimental Pharmacology) [in Russian], DAR, Ufa, 2001, p. 218.

    Google Scholar 

  7. S. A. Grabovskiy, Yu. I. Murinov, and N. N. Kabal′nova, Curr. Org. Chem., 16, 2389 (2012).

    Article  CAS  Google Scholar 

  8. G. R. Akhatova, I. V. Safarova, and A. Ya. Gerchikov, Kinet. Catal., 52, 1 (2011).

    Article  CAS  Google Scholar 

  9. L. R. Yakupova, R. A. Sakhautdinova, E. Yu. Pankratyev, and R. L. Safiullin, Kinet. Catal., 53, 665 (2012).

    Article  CAS  Google Scholar 

  10. R. Amorati, L. Valgimigli, G. F. Pedulli, S. A. Grabovskiy, N. N. Kabal′nova, and C. Chatgilialoglu, Org. Lett., 12, 4130 (2010).

    Article  CAS  PubMed  Google Scholar 

  11. L. F. Tietze and T. Eicher, Preparative Organic Chemistry [translated from Ger.], Mir, Moscow, 1999, p. 504 [Reactionen und Synthesen im Organisch-Chemischen Praktikum und Forschungs Laboratorium, New York, 1991].

  12. Z. A. Martirosyan, V. I. Gyunar, and S. I. Zav′yalov, Izv. Akad. Nauk SSSR, Ser. Khim., 8, 1841 (1970).

    Google Scholar 

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Acknowledgment

The work was supported financially by a grant from the 2014 competition in RSF priority activity area “Basic research and discovery by individual scientific groups” (Appl. No. 14-13-01307). Informational support used RFBR grant 13-00-14056. Spectral studies and theoretical calculations were performed on equipment of the Khimiya CCU at UIC, RAS.

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Correspondence to I. B. Chernikova.

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Translated from Khimiya Prirodnykh Soedinenii, No. 4, July–August, 2017, pp. 608–610.

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Chernikova, I.B., Spirikhin, L.V., Lobov, A.N. et al. Reaction of 5-Hydroxymethyl-6-Methyluracil with Toluenesulfonyl Chloride or Methanesulfonyl Chloride and Tertiary Amines. Chem Nat Compd 53, 714–716 (2017). https://doi.org/10.1007/s10600-017-2097-x

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  • DOI: https://doi.org/10.1007/s10600-017-2097-x

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