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Synthesis and Physicochemical and Biological Properties of 8-Amino-Substituted 7-(2-Hydroxy-3-p-Methoxyphenoxypropyl-1)Theophyllines

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Chemistry of Natural Compounds Aims and scope

A method was developed to prepare previously unreported 8-amino-substituted (2-hydroxy-3-p-methoxyphenoxypropyl-1)theophyllines as potential biologically active compounds. Their physicochemical properties; acute toxicity; and diuretic, anti-inflammatory, analgesic, and antihypoxic activity were studied.

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Authors and Affiliations

  1. Zaporozhye State Medical University, 26 Prosp. Mayakovskogo, Zaporozhye, 69035, Ukraine

    N. I. Romanenko, D. G. Ivanchenko & T. A. Sharapova

  2. National Pharmaceutical University, 53 Pushkinskaya St., Kharkov, 61002, Ukraine

    B. A. Samura & E. A. Duchenko

Authors
  1. N. I. Romanenko
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  2. D. G. Ivanchenko
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  3. B. A. Samura
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  4. E. A. Duchenko
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  5. T. A. Sharapova
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Corresponding author

Correspondence to D. G. Ivanchenko.

Additional information

Translated from Khimiya Prirodnykh Soedinenii, No. 4, July–August, 2017, pp. 595–598.

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Romanenko, N.I., Ivanchenko, D.G., Samura, B.A. et al. Synthesis and Physicochemical and Biological Properties of 8-Amino-Substituted 7-(2-Hydroxy-3-p-Methoxyphenoxypropyl-1)Theophyllines. Chem Nat Compd 53, 698–702 (2017). https://doi.org/10.1007/s10600-017-2094-0

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  • DOI: https://doi.org/10.1007/s10600-017-2094-0

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