A new furanocoumarin, 5-(2″,3″-dihydroxy-3″-methylbutyloxy)-8-(2″′-hydroxy-3″′-methyl-3″′-butylenoxy)-psoralen, named oncosepalin B (1), was isolated from the roots of Angelica oncosepala. The structure of the new compound was identified on the basis of spectroscopic methods, especially extensive 1D and 2D NMR spectra analysis. Compound 1 showed weak inhibition of HL-60 human tumor cell line with an IC50 value of 17.05 μM.
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Acknowledgment
This work was financially supported by the Natural Science Foundation of Yunnan Province (No. 2011FB058) and the National Natural Science Foundation of China (No. 21102060).
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Published in Khimiya Prirodnykh Soedinenii, No. 2, March–April, 2014, pp. 223–224.
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Qing, C., Zhou, YP., Zi, R. et al. A New Furanocoumarin from the Roots of Angelica oncosepala . Chem Nat Compd 50, 251–253 (2014). https://doi.org/10.1007/s10600-014-0924-x
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DOI: https://doi.org/10.1007/s10600-014-0924-x