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A New Coumarin from Zanthoxylum nitidum

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Chemistry of Natural Compounds Aims and scope

One new coumarin compound, isopranferin (1), along with six known compounds 2–7, were isolated from Zanthoxylum nitidum. Their structures were determined on the basis of spectral data including 1D and 2D NMR and HR-EI-MS. Compounds 2–4, 6, and 7 were isolated from this plant for the first time. The in vitro cytotoxicity of compounds 1–7 to RAW264.7 cells, THP-1 cells, and Caco-2 cells was firstly tested by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) methods.

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Acknowledgment

We gratefully acknowledge the financial support of this work by National Key Project of Science and Technology of China “Important New Drugs Innovation,” 2017ZX09301045, Strategic Priority Research Program of the Chinese Academy of Sciences, XDA12050302, XDA12040321, and Foundation of XTBG, 2017XTBG-F02. This work was also supported by the Strategic Biological Resources Service Network Plan of the Chinese Academy of Sciences, ZSTH-022, and Foundation of Yunnan Natural Science, 2014FA043.

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Authors and Affiliations

  1. Key Laboratory of Tropical Plant Resources and Sustainable Use, Xishuangbanna Tropical Botanical Garden, Chinese Academy of Sciences, 650223, Kunming, P. R. China

    Lan Zhou, Wenqian He, Yumei Zhang, Pianchou Gongpan, Qingfei Fan & Qishi Song

  2. University of Chinese Academy of Sciences, 100049, Beijing, P. R. China

    Lan Zhou, Wenqian He & Qingfei Fan

  3. College of Biology and Chemistry, Puer University, Puer, 665000, Yunnan, P. R. China

    Wencui Chen

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  1. Lan Zhou
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  2. Wencui Chen
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  3. Wenqian He
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  4. Yumei Zhang
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  5. Pianchou Gongpan
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  6. Qingfei Fan
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  7. Qishi Song
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Corresponding authors

Correspondence to Qingfei Fan or Qishi Song.

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Published in Khimiya Prirodnykh Soedinenii, No. 6, November–December, 2019, pp. 871–873.

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Zhou, L., Chen, W., He, W. et al. A New Coumarin from Zanthoxylum nitidum. Chem Nat Compd 55, 1010–1013 (2019). https://doi.org/10.1007/s10600-019-02881-7

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  • DOI: https://doi.org/10.1007/s10600-019-02881-7

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