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Effective synthesis of methyl 3β-amino-3-deoxybetulinate

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Chemistry of Natural Compounds Aims and scope

A practical method for preparing methyl 3β-amino-3-dexoybetulinate that is based on column chromatographic separation of 3α- and 3β-t-butoxycarbonates and subsequent removal of the protecting group using formic acid is proposed. The structure of methyl 3β-N-(t-butoxycarbonyl)-3-deoxybetulinate was established by an x-ray structure analysis.

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Acknowledgment

The work was supported financially by the RFBR (Project No. 08-03-00868).

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Authors and Affiliations

  1. Institute of Organic Chemistry, Ufa Scientific Center, Russian Academy of Sciences, 450054, Ufa, prosp. Oktyabrya, 71, Russia

    G. V. Giniyatullina, O. B. Flekhter, I. P. Baikova & G. A. Tolstikov

  2. N. A. Nesmeyanov Institute of Elementorganic Compounds, RAS, Moscow

    Z. A. Starikova

Authors
  1. G. V. Giniyatullina
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  2. O. B. Flekhter
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  3. I. P. Baikova
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  4. Z. A. Starikova
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  5. G. A. Tolstikov
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Corresponding author

Correspondence to O. B. Flekhter.

Additional information

Translated from Khimiya Prirodnykh Soedinenii, No. 5, pp. 488–490, September-October, 2008.

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Giniyatullina, G.V., Flekhter, O.B., Baikova, I.P. et al. Effective synthesis of methyl 3β-amino-3-deoxybetulinate. Chem Nat Compd 44, 603–605 (2008). https://doi.org/10.1007/s10600-008-9138-4

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  • DOI: https://doi.org/10.1007/s10600-008-9138-4

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